Poster Session Listing

Physiology: Aging and Stress

203A. The novel regulators of RNT-1 stabilization in stress response. Soungyub Ahn, Kiho Lee, Peter Swoboda, Junho Lee.

204B. Trade-offs and bet-hedging in reproductive performance during heat stress. Erin Zucker Aprison, Ilya Ruvinsky.

205C. Protective effect of Paullinia cupana, the Guarana, on Caenorhabditis elegans under oxidative stress. Leticia P. Arantes, Marina Machado, Daniele Zamberlan, Cintia Tassi, João da Rocha, Felix Soares.

206A. Evaluation of the activity of Luehea divaricata Mart. leaf extract against different pro-oxidants in Caenorhabditis elegans . Leticia P. Arantes, Dirleise Colle, Marina Machado, Cintia Tassi, Daniele Zamberlan, Ritiel da Cruz, João da Rocha, Melânia Manfron, Margareth Athayde, Felix Soares.

207B. Screening of antioxidant organochalcogen compounds in Caenorhabditis elegans: focus on modulation of DAF-16/FOXO pathway. Daiana S. Avila, Suzi Wollenhaupt, Ana Thalita Soares, Willian Salgueiro, Diego Avila.

208C. Role of amino-acid pool size in aging-related muscle atrophy. Meenakshisundaram Balasubramaniam, Ramani Alla, Robert J. Shmookler Reis, Srinivas Ayyadevara.

209A. Microfluidic devices for electrical measures of pharyngeal health. Stephen A. Banse, John. H. Willis, Kristin J. Robinson, Janis C. Weeks, Patrick C. Phillips, Shawn R. Lockery.

210B. Persistent effects of starvation on multiple life history traits. Moses Sandrof, Meghan Jobson, James Jordan, Ryan Baugh.

211C. RER-1 - Finding New Roles For An Old Protein. Kunal Baxi, Ata Ghavidel, Troy Harkness, Carlos Carvalho.

212A. 7-ketocholesterol acts through steroid receptor DAF-12 to regulate dauer formation and longevity. Ben Becker, Adam Antebi.

213B. Identifying the role of apl-1 through an RNAi Screen and Mosaic Analysis. Maisam T. Begum, Pei Zhao, Chris Li.

214C. Modulation of HIF-1 activity and its effect on stress tolerance and longevity in C. elegans. P. Bharill, F. Fabretti, H. Gharbi, B. Schermer, T. Benzing, R. Mueller.

215A. The Mechanistic Basis of Neuroendocrine Control of Longevity. Konstantinos Boulias, Bob Horvitz.

216B. Proteomics approach to identify potential targets of tyrosol, an olive oil phenol that stimulates longevity and stress resistance in Caenorhabditis elegans. Ana Cañuelo, J. Peragón, P. Pacheco.

217C. Mutations in the Translation Initiation Factor Subunit eIF-3.k Suppress the Stress Sensitivity of xbp-1 Mutants. Douglas Cattie, Kirthi Reddy, Claire Richardson, Dennis Kim.

218A. Biological behavior of carbon nanoparticles in Caenorhabditis elegans. Yun Jeong Cha, Shin Sik Choi.

219B. Novel Kinases that interact with the Insulin-IGF-1-like signaling pathway to control longevity. Manish Chamoli, Awadhesh Pandit, Mukund Sudharsan, Arnab Mukhopadhyay.

220C. Characterization of a gene whose expression correlates with the food type-dependent effects on lifespan. Wolfgang Maier, Rashmi Chandra, Joy Alcedo.

221A. daf-16/FoxO isoform-specific mutants reveal differential contributions to longevity in the contexts of reduced DAF-2 insulin-like signaling and germline ablation. Albert Chen, Chunfang Guo, Kathleen Dumas, Travis Williams, Sawako Yoshina, Shohei Mitani, Patrick Hu.

222B. Effects of C. elegans sgk-1 mutations on life span, stress resistance, and DAF-16/FoxO regulation. Albert Chen, Chunfang Guo, Kathleen Dumas, Kaveh Ashrafi, Patrick Hu.

223C. Sestrin confers the regulations of muscle aging and lifespan in Caenorhabditis elegans. Ya-Luen Yang, Kah-Sin Loh, Bang-Yu Liou, I-Hua Chu, Cheng-Ju Kuo, Huan-Da Chen, Chang-Shi Chen.

224A. The Effect of Hydrolysable Tannins from Eucalyptus Leaves on C. elegans Lifespan. Y. chen, B. Onken, H. Chen, Q. Huang, S. Xiao, M. Driscoll, Y. Cao.

225B. Nutritional Control of Insulin-Like Peptide Expression during L1 Arrest and Recovery. Yutao Chen, Ryan Baugh.

226C. Transcriptional profiling reveals a principle role for wdr-23 in regulating SKN-1 and potential interactions with molting and the cuticle. Lanlan Tang, Andrew Deonarine, Chi K. Leung, Keith P. Choe.

227A. Peroxide Stress Response and Ferritin Synthesis Regulation by the REF-1 Family Member HLH-29. H. T. Chou, T. K. Quach, C. M. Johnson.

228B. Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging. A. Dallaire, C. Garand, E. R. Paquet, S. J. Mitchell, R. De Cabo, M. J. Simard, M. Lebel.

229C. Activation of the hexosamine pathway improves ER protein quality control and slows aging. Martin S. Denzel, Nadia J. Storm, Adam Antebi.

230A. Proteostasis in the aging model Caenorhabditis elegans. I. Dhondt, G. Depuydt, H. Cai, J. Staal, A. Borghi, L. Verstrepen, L. Baten, R. Beyaert, B. P. Braeckman.

231B. Pharmacological enhancers of physical activity and their impact on metabolic functions and longevity in C. elegans. Sharon Epstein, Matthew McGee, Pankaj Kapahi.

232C. An underlying dauer-independent DAF-2 longevity program implicates collagen homeostasis in longevity. Collin Ewald, Jess Landis, Jess Porter Abate, Coleen Murphy, T. Keith Blackwell.

233A. Adaptation to hydrogen sulfide induces a reversible developmental plasticity in C. elegans. Emily Fawcett, Dana Miller.

234B. Examining neuromuscular deficits and oxidative damage after exposure to common anthropogenic chemicals in Caenorhabditis elegans. Denise B. Flaherty, Christopher W. Dukes, Seth V. Malhotra, Ashlin L. Niedzwiecki, Daniel C. Kovarik, Julia M. Billington.

235C. Lysosomal lipolysis promotes longevity through a lipid-responsive nuclear hormone receptor signaling pathway. Andrew Folick, Holly Doebbler, Yong Yu, Meng Wang.

236A. Genes that Affect Glucose-Fed C. elegans Exposed to Oxygen-Deprivation. Anastacia Garcia, Pamela Padilla.

237B. Role of Autophagy in Long-lived C. elegans Subjected to Dietary Restriction. Sara Gelino, Jessica Chang, Malene Hansen.

238C. Quasi-programmed yolk synthesis contributes to C. elegans aging. Yila de la Guardia, Eleanor Tyler, Alex Benedetto, David Gems.

239A. Characterizing Adult Reproductive Diapause Longevity. B. Gerisch, D. Magner, A. Antebi.

240B. The Dual Roles of TCER-1/TCERG1 in Balancing Reproductive Fitness and Longevity. Francis RG Amrit, Arshi Arora, Takis Benos, Arjumand Ghazi.

241C. Genetics of praziquantel resistance in C. elegans. Rajarshi Ghosh, Anya Levinson, Conrad Tenenbaum, Leonid Kruglyak.

242A. The Mediator subunit MDT-15 is required for the oxidative stress response. Grace Y. S. Goh, Kulveer S. Parhar, Ada W. L. Kwong, Marcus A. Wong, Stefan Taubert.

243B. Proteotoxicity Models of Transthyretin Amyloid Disease in C. elegans. E. Greiner, J. Paulsson, S. Choi, S. Wolff, D. Ong, A. Dillin, S. Encalada, J. Kelly.

244C. The neuroglobin GLB-5 regulates C. elegans responses to hypoxic exposure. E. Gross, Z. Soltesz, V. Zelmanovich, M. de-Bono.

245A. SIR-2.1, an HDAC, is required to maintain male mating ability during aging of C. elegans. Xiaoyan Guo, Luis Rene Garcia.

246B. Bacterial nitric oxide extends C. elegans lifespan. Ivan Gusarov, Laurent Gautier, Olga Smolentseva, Ilya Shamovsky, Svetlana Eremina, Alexander Mironov, Evgeny Nudler.

247C. Temperature-dependent effects of C. elegans N-acylethanolamine biosynthetic enzymes. Neale Harrison, Ifedayo Victor Ogungbe, Pedro Reis-Rodrigues, Thomas Gallagher, Young-Jai You, Matthew S. Gill.

248A. The E3 Ligase LIN-23/βTRCP Influences SKN-1/NRF2 Activity and Reduces Toxic Proteins in daf-2 Mutants. Kyle Holden, Emmanuel Schrieber, Mani Balasubramani, Arjumand Ghazi.

249B. Profiling of genotoxic stress response of C. elegans and investigation of protective effects of selected natural compounds. S. Honnen, C. Henninger, C. Büchter, Y. Chovolou, P. Proksch, G. Fritz.

250C. A Novel Link between Ubiquitin-dependent Proteolysis and Mitochondrial Metabolism. Thorsten Hoppe, Alexandra Segref.

251A. The Caenorhabditis elegans homolog of co-chaperone p23/prostaglandin E synthase-3 regulates lifespan in response to temperature. M. Horikawa, A. Antebi.

252B. Translational Effect of Hydrogen Sulfide and a Novel Role for HIF-1. Joe Horsman, Dana Miller.

253C. SAMS-1: A protein that senses nutrient levels and mediates the longevity response to dietary restriction in the intestine. Tsui-Ting Ching, Alex Kramer, Alisha Paal, Linda Zhang, Ao-Lin Hsu.

254A. The role of C. elegans BRAP-2 in the SKN-1 mediated oxygen radical detoxification response. Queenie Hu, Lesley MacNeil, Marian Walhout, Terrance J. Kubiseski.

255B. Nanoparticle size, shape, coat, and charge alter the bioactivity of nanosilver in C. elegans. Piper R. Hunt, Steven J. Oldenburg, Nicholas Olejnik, Robert L. Sprando.

256C. Analysis of miro-1. Takao Inoue, Yanqing Shen, Natarie Pei Wen Low, Thilo Hagen, Li Fang Ng, Jan Gruber.

257A. AMPK regulates protein homeostasis in response to hypoxia and nutrient deprivation. Nicole Iranon, Dana Miller.

258B. Genes that influence longevity, dauer formation and pathogen responses downstream of sensory neurons in C. elegans. Dae-Eun Jeong, Marta M. Gaglia, Eun-A Ryu, Dongyeop Lee, Cynthia Kenyon, Seung-Jae Lee.

259C. nhr-176 regulates cyp-35d1 to control hydroxylation-dependent metabolism of thiabendazole in C. elegans. Laura M. Jones, Anthony Flemming, Peter E. Urwin.

260A. Modulation of the Ubiquitin-Proteasome System and C. elegans Longevity by Neuroendocrine and Growth Factor Signaling Pathways. Kishore K. Joshi, Tejash Shah, Christopher Rongo.

261B. Role of mir-35-41 family in embryonic development and hypoxia. Konstantinos Kagias, Roger Pocock.

262C. LEA genes in Antarctic nematode, Panagrolaimus davidi. Hiroshi Kagoshima, Yuji Kohara.

263A. 20-hydroxyecdysone prevents age-associated decline in C. elegans . Shaunak Kamat, Shrutika Yeola, Monica Driscoll.

264B. Quest for life-lengthening signals within gonadal longevity. Oezlem Karalay, Shuhei Nakamura, Adam Antebi.

265C. The HIF-1 Pathway and organismal senescence. Jordan Kardos, Sudhir Nayak.

266A. C. elegans EXO-3 contributes to progeny production by repairing AP site in gonad. Yuichi Kato, Takahito Moriwaki, Masafumi Funakoshi, Qiu-Mei Zhang-Akiyama.

267B. TAF-4 is Required for the Life Extension of isp-1, clk-1 and tpk-1 Mit Mutants. Maruf H. Khan, Lauren Temmer, Melissa Ligon, Bryce Hufnal, Robert Farber II, Andrew Dillow, Erynn Kahlig, Amanda Rodriguez, Shane L. Rea.

268C. Fat, reproduction and longevity phenotypes associated with altered protein synthesis capacity. Akshat Khanna, Sean P. Curran.

269A. Gene expression studies to evaluate the size related toxicity of ZnO nanoparticles on the soil nematode, Caenorhabditis elegans. Priyanka Khare, Madhavi Sonane, K. C. Gupta, Aruna Satish.

270B. Characterization of changes in metal composition in C. elegans with age. Ida M. Klang, David Killilea, Tracy Barhydt, Peter Swoboda, Daniel Edgar, Gordon Lithgow.

271C. Natural genetic polymorphisms in set-15 and a casein kinase 1α homolog shape the mortality schedule of worms. Gunnar Kleemann, Hua-Jay Cherng, Alina Yang, Thomas Kuhlman, Joshua Bloom, Edward Cox, Leonid Kruglyak, Coleen Murphy.

272A. Molecular aging driven by Wnt signaling in C. elegans. B. Koenders- van Sintanneland, M. Lezzerini, Y. Budovskaya.

273B. Age-related degeneration of the egg-laying system promotes matricidal hatching in Caenorhabditis elegans. Christopher L. Pickett, Kerry Kornfeld.

274C. Regulation of the ER Stress Response by HPL-2 and other chromatin associated proteins in Caenorhabditis elegans . Lucie Kozlowski, Steve Garvis, Cécile Bedet, Francesca Palladino.

275A. Age-dependent neuronal changes are the result of multiple intrinsic and extrinsic factors. Anagha Kulkarni, Claire Bénard.

276B. An ACE inhibitor extends Caenorhabditis elegans life span. Sandeep Kumar, Nicholas Deitrich, Kerry Koenfeld.

277C. Integrin-linked kinase regulates longevity and thermo-tolerance via HSF-1 in C. elegans. C. Kumsta, A. Davis, T.-T. Ching, M. Nishimura, C.-C. Chu, S. Gelino, B. Ong, R. Bodmer, A.-L. Hsu, M. Hansen.

278A. The Impact of Age and Lipid Stores: An Analysis of Oxygen Deprivation Response in C. elegans. M. L. Ladage, J. M. Goy, V. Shulaev, P. A. Padilla.

279B. SIR-2.1 regulation by the NAD+ Salvage Pathway and Environmental Stress. Stephanie E. Lange, Wendy Hanna-Rose.

280C. DNA damage leads to replicative aging but extends lifespan of long lived mutant animals. Jessica M. Lindvall, Karen Thijssen, Andrea E. Karambelas, Daniel Cupac, Øyvind Fensgård, Gert Jansen, Jan H. J. Hoeijmakers, Hilde Nilsen, Wim Vermeulen, Hannes Lans.

281A. Dissecting Ageing-Related Pathways by Studying Protein Changes after Calorie Restriction. Mark Larance, Ehsan Pourkarimi, Anton Gartner, Angus Lamond.

282B. Mutations in ribosomal S6 kinase lengthen lifespan through increasing the activity of heat shock transcription factor 1. Keunhee Seo, Eunseok Choi, Dongyeop Lee, Dae-Eun Jeong, Sung Key Jang, Seung-Jae Lee.

283C. Investigating the role of the wrn-1 helicase in the nematode worm, C. elegans. Hayley Lees, Alison Woollard, Lynne Cox.

284A. Development of small molecule inhibitors of SKN-1 dependent detoxification genes identified in a screen of ~364,000 compounds. Chi K. Leung, Satyamaheshwar Peddibhotlal, Patrick Maloney, Paul M. Hershberger, Michelle Bousquet, Hendrik Luesch, Siobhan Malany, Keith P. Choe.

285B. A dual role of the Wnt signaling pathway during aging in Caenorhabditis elegans. M. Lezzerini, Y. Budovskaya.

286C. Characterization of novel mutants with dysfunctional mitochondrial stress pathways. Jacqueline Lo, Sean P. Curran.

287A. New roles for wdr-23 in organismal survival and stress adaptation. Jacqueline Lo, Akshat Khanna, Elaine Roh, Megan Bernstein, Sean P. Curran.

288B. Exploring the health benefits of phytoestrogens in C. elegans. Jessica M. Ochoa, Vanessa Parada, Gabriela Gutierrez, Breann De Santiago, Erika Perez, Peaches Ulrich, Emanuel Zamora, Sylvia A. Lopez-Vetrone.

289C. Investigating the Toxic Effect of Biosensor Nanoparticles Using the Caenorhabditis elegans Nematode. Michelle Callaway, Erika Perez, John D. Alocilja, Evangelyn Alocilja, Sylvia A. Lopez-Vetrone.

290A. Drift of ELT-2 as a cause of aging in C. elegans. Frederick G. Mann, Eric Van Nostrand, Ari Friedland, Stuart Kim.

291B. Modulation of Excitotoxic Neurodegeneration in C. elegans by the Cell Stress-Resistance Signaling Pathway. Nazila Tehrani, Moises Dominguez, Itzhak Mano.

292C. Vitamin D3 slows aging in c. elegans. Karla Mark, Dipa Bhaumik, Milena Price, Birgit Schilling, Bradford Gibson, Michael Holick, Gordon Lithgow.

293A. Insulin/IGF-1 Signaling Regulates Proteasome Activity through the Deubiquitinating Enzyme UBH-4. Olli Matilainen, Leena Arpalahti, Ville Rantanen, Sampsa Hautaniemi, Carina I. Holmberg.

294B. A redox sensor as a potential regulator of ROS signaling in C. elegans. Katie McCallum, Antonio Miranda-Vizuete, Danielle Garsin.

295C. Does iron dyshomeostasis drive ageing? Gawain McColl, B. R. Roberts, S. A. James, R. A. Cherny, A. I. Bush.

296A. Exploring the Flexibility of NAD+ Biosynthesis in C. elegans. Melanie R. McReynolds, Wendy Hanna-Rose.

297B. Sugar Stress Reduces Fertility in C. elegans via Multiple Mechanisms. Marjorie R. Liggett, Amanda K. Engstrom, Uyen Ho, Michael Mastroianni, Michelle A. Mondoux.

298C. A novel kinase regulates dietary restriction-mediated longevity in C. elegans. Arnab Mukhopadhyay, Manish Chamoli, Anupama Singh.

299A. Regulation of self-renewal and differentiation capacities of germline stem cells during ageing. Patrick Narbonne, Jean-Claude Labbé, Paul S. Maddox.

300B. A role for the insulin signaling pathway in development of neuronal aging markers in a polyglutamine protein aggregation C. elegans model. Courtney Rose Nichols, Elena Vayndorf, J. Alex Parker, Christian Neri, Monica Driscoll, Barbara Taylor.

301C. Oligomeric proanthocyanidins extracts are putative anti-obesity targets in the nematode Caenorhabditis elegans. Yu Nie, Sukhi Bansal, Bob Hider, Peter Hylands, Stephen Stürzenbaum.

302A. HIF-independent processes in hypoxia in C.elegans. Divya Padmanabha, Young-Jai You, Keith Baker.

303B. The inner mitochondrial membrane translocase complex TIM23 modulates mitochondrial biogenesis and function during ageing in C. elegans. E. Lionaki, K. Palikaras, N. Tavernarakis.

304C. Coordination of mitophagy and the mitochondrial retrograde response during ageing in C. elegans. Konstantinos Palikaras, Nektarios Tavernarakis.

305A. Mitochondrial Dynamics And Behavioral Plasticity In Response To Oxygen Deprivation Are Linked Through HIF-1. Eun Chan Park, Piya Ghose, Alexandra Tabakin, Nathaly Salazar-Vasquez, Christopher Rongo.

306B. Independent genetic pathways for stress response and longevity revealed by experimental evolution in the nematode Caenorhabditis remanei. Rose Reynolds, Kristin Sikkink, Catherine Ituarte, Janna Fierst, John Willis, William Cresko, Patrick Phillips.

307C. Deciphering the microRNA responses to high temperature stress. C. Nehammer, A. Podolska, K. Kagias, S. Mackowiak, N. Rajewski, R. Pocock.

308A. Folliculin is an evolutionary conserved regulator of AMPK function. E. Possik, Z. Jalali, Y. Nouet, M. Yan, MC. Gingras, L. Chotard, F. Dupuy, C. Rocheleau, D. Hall, R. Jones, A. Pause.

309B. Epigenetic Mechanism of Longevity Regulation in C. elegans. Mintie Pu, Xiujuan Wang, Zhuoyu Ni, Haiyuan Yu, Siu Sylvia Lee.

310C. The mitochondrial stress machinery protects cells from inhibition of the mevalonate pathway. Manish Rauthan, Marc Pilon.

311A. Is mitochondrial fragmentation a bio marker of aging? Saroj G. Regmi, Barbara Conradt.

312B. Regulation of eIF4E compartmentalization by the heat shock response pathway during ageing in C. elegans. M. Rieckher, A. Princz, N. Tavernarakis.

313C. Systemic control of the cytosolic redox environment in C. elegans. C. Romero, W. Fontana, J. Apfeld.

314A. Developmental Exposure to Ultraviolet C Radiation Results in Altered Energy Production Later in Life in Caenorhabditis elegans. John P. Rooney, Rakesh Bodhicharla, Amanda Bess, Maxwell Leung, Ian Ryde, Alex Ji, Joel Meyer.

315B. Assaying nickel toxicity using nematodes. David Rudel, Ian Huffnagle, Chandler Douglas, John Atkinson.

316C. D-Aspartate oxidase is involved in the caloric restriction-induced lifespan extension in C. elegans. Yasuaki Saitoh, Mari Okutsu, Masumi Katane, Masae Sekine, Takemitsu Furuchi, Taro Sakamoto, Takao Inoue, Hiroyuki Arai, Hiroshi Homma.

317A. Genetic analyses of hypoxia response and the roles of HIF-1. Jenifer Saldanha, Dingxia Feng, Korinna Radke, Jo Anne Powell-Coffman.

318B. The Max/Mlx transcriptional network influences aging in C. elegans. David W. Johnson, Jesse Llop, Sara Farrell, Andrew V. Samuelson.

319C. ULP-4 SUMO protease controls HMGS-1 activity in cytosolic and mitochondrial metabolic networks during development, aging, and stress. Amir Sapir, Assaf Tsur, Thijs Koorman, Mike Boxem, Paul Sternberg, Limor Broday2.

320A. Using C. elegans to explore the role of presenilin in the pathogenesis of Alzheimer’s Disease. Shaarika Sarasija, Kenneth Norman.

321B. The rare sugar D-psicose extends Caenorhabditis elegans lifespan by increasing oxidative stress resistance. M. Sato, H. Sakoguchi, T. Shintani, K. Okuma, K. Izumori.

322C. DNA damage responses in development and ageing. Michael Mueller, Laia Castells-Roca, Maria Ermolaeva, Peter Frommolt, Sebastian Greiss, Jennifer Schneider, Björn Schumacher.

323A. Gut-specific regulation of transcription in long-lived daf-2 mutants. Lamia M. Boukhibar, Zoja Nagurnaja, Nuria Vergara Irigaray, Eugene F. Schuster.

324B. Environmental Stress Resistance in exl-1 and dbl-1 Mutants of C. elegans. Yakov Shaulov, Tasmia Hoque, Jun Liang Rice, Cathy Savage-Dunn.

325C. Mitoflash is an Early Predictor of Lifespan in C. elegans. Enzhi Shen, Chunqing Song, Yuan Lin, Wenhong Zhang, Peifang Su, Wenyuan Liu, Pan Zhang, Jiejia Xu, Na Lin, Cheng Zhan, Xianhua Wang, Yu Shyr, Heping Cheng, Mengqiu Dong.

326A. The role of autophagy in lipid and mitochondrial homeostasis. Melissa J. Silvestini, Hannah Hong, Alicia Meléndez.

327B. Assessing drug induced mitochondrial toxicity using C. elegans. Reuben L. Smith, Richard de Boer, Winnok H. de Vos, Erik M. Manders, Stanley Brul, Hans van der Spek.

328C. Effect of chronic treatment with amphetamine in an experimental model using Caenorhabditis elegans. Tássia Fontana Lehmen, Bruna Puntel, Priscila Gubert, Roselei Fachinetto, Félix A. A. Soares.

329A. ROS and antioxidant interaction in C. elegans. Paul Neal Stein, Craig W. LaMunyon.

330B. A genetic screen for stress resistance combined with next-generation sequencing reveals new longevity candidates. Nadia J. Storm, Martin S. Denzel, Adam Antebi.

331C. Quantitative analysis of ionizing radiation-induced effects on locomotion in Caenorhabditis elegans. Michiyo Suzuki, Tetsuya Sakashita, Toshio Tsuji, Yuya Hattori, Yasuhiko Kobayashi.

332A. Mitochondrial dynamics in response to oxygen deprivation. Alexandra L. Tabakin, Piya Ghose, Eun Chan Park, Nathaly Salazar-Vasquez, Christopher Rongo.

333B. Quiescence of entomo-phoretic nematode Caenorhabditis japonica. R. Tanaka, Y. Hirooka, T. Kikuchi, N. Kanzaki.

334C. Fructose accelerates neuronal aging in C. elegans. Marton Toth, Leena Shah, Monica Driscoll.

335A. Calcium Exerts Critical Functions in Adult Neuronal Maintenance. Marton Toth, Ivana Ganihong, Khushboo Patel, Kelli Gaul, Camisha DuBose, Steven Kim, Saurabh Patel, Wenying Zhang, Jian Xue, Monica Driscoll.

336B. Regulation of organismal proteostasis by trans-cellular chaperone signaling. Patricija van Oosten-Hawle, Robert S. Porter, Richard I. Morimoto.

337C. Protein homeostasis dysregulation drives aberrant morphology of aging mechanosensory neurons. Elena Vayndorf, Courtney Nichols, Cyrena Parker, Skyler Hunter, Marton Toth, J. Alex Parker, Christian Neri, Monica Driscoll, Barbara Taylor.

338A. Genome-wide study of stress-responsive microRNA and mRNA transcriptomes in C. elegans. Maria C. Ow, Isana Veksler-Lublinsky, Victor Ambros.

339B. Investigating progranulin in aging and neurodegeneration. Julie Vérièpe, J. Alex Parker.

340C. Age-dependent Proteome Turnover Changes in C. elegans. K. Vukoti, X. Yu, J. Feng, A. Hsu, M. Miyagi.

341A. Direct Regulation of HIF-1 by the Metabolic Network in C. elegans. Robert J. Mishur, Maruf Khan, Haley M. Willhelm, Shane L. Rea.

342B. Intermittent hyperoxia-induced hormesis decreases aerobic respiration via ins/IGF-1 and p53/CEP-1 signalings in C. elegans. Sumino Yanase, Tetsuji Shoyama, Hitoshi Suda, Naoaki Ishii.

343C. Genetic mechanism of carotenoid nanoparticle-induced health promotion effects in Caenorhabditis elegans. Ji Suk You, Yeong Hun Kim, Sang Ho Koo, Shin Sik Choi.

344A. C. elegans SIRT6/7 homolog SIR-2.4 promotes stress response and longevity via distinct mechanisms. Wei-Chung Chiang, Xiaokun Yu, Daniel X. Tishkoff, Bo Yang, Tsui-Ting Ching, David B. Lombard, Ao-Lin Hsu.

345B. The Rosmarinus officinalis extract protects against oxidative stress and increase C. elegans lifespan. D. C. Zamberlan, G. P. Amaral, S. T. Stefanello, R. L. Puntel, F. A. A. Soares.

346C. Neutral cholesterol ester hydrolase 1 is protective against α-synuclein-induced toxicity in C. elegans. S. Zhang, K. A. Caldwell, G. A. Caldwell.

347A. Identification of genes that regulate the ribotoxic stress response in Caenorhabditis elegans. Yan Qi, Xinrui Zhang, Natalia Kirienko, Peter Breen, Holli Rowedder, Gary Ruvkun.

348B. Delineating AMPK and TOR longevity. Yue Zhang, Ianessa Morantte, William Mair.

349C. A quantitative proteomic analysis of aging in C. elegans. Stephanie M. Zimmerman, Izumi V. Hinkson, Joshua E. Elias, Stuart K. Kim.

Physiology: Dauer Larvae and Metabolism

350A. Analysis of the CRTC1 pathway in fat regulation of C. elegans. Sravya Challa, Rebecca Hintz, Alexander van der Linden.

351B. Multiple Insulin-like Ligands Regulate the Insulin/IGF Receptor Activity to Prevent Dauer Formation. Jyothsna D. Chitturi, Wesley L. Hung, Ying Wang, Mei Zhen.

352C. Regulation of Metabolism by TGF-β Signaling in C. elegans. James F. Clark, Vanessa Almonte, Cathy Savage-Dunn.

353A. Post-embryonic control of DAF-2 insulin-like signaling by the conserved dosage compensation protein DPY-21. Kathleen Dumas, Colin Delaney, Stephane Flibotte, Donald Moerman, Gyorgyi Csankovszki, Patrick Hu.

354B. A novel role for the p120RasGAP family member GAP-3 in dauer regulation. Kathleen Dumas, Joseph Kruempel, Stephane Flibotte, Donald Moerman, Patrick Hu.

355C. Synthetic cannabinoids influence dauer formation via insulin peptides. Neale Harrison, Pedro Reis-Rodrigues, Mark Lucanic, Jason M. Held, Gordon J. Lithgow, Thomas Gallagher, Young-Jai You, Matthew S. Gill.

356A. Metabolic effects of manganese in the nematode Caenorhabditis elegans.. Priscila Gubert, Bruna Bruna, Tassia Lehmen, Daiana Avila, Felix Soares, Michael Aschner.

357B. Glycosphingolipid mediates clozapine-induced developmental delay and lethality in C. elegans. Limin Hao, Bruce Cohen, Edgar Buttner.

358C. Regulation of fat and body growth by SIKs and class II HDACs. Rebecca Hintz, Sravya Challa, Faye Schilkey, Alexander van der Linden.

359A. The Mediator subunit MDT-15 is required for maintenance of membrane lipid unsaturation and ER homeostasis. Nicole S. Hou, Stefan Taubert.

360B. The C. elegans Insulin Signaling Response to Glucose Stress Requires Unique Regulators. Michael James Hoy, Brian Ganley, John A. Hanover, Michael W. Krause, Michelle A. Mondoux.

361C. A CaMK signaling cascade modulates pheromone-mediated developmental plasticity. In-sok Hwang, Zhi Fang, Piali Sengupta, Kyuhyung Kim.

362A. Epigenetic regulation of stress response in C. elegans. Moonjung Hyun, Catherine Dumur, Young-jai You.

363B. Targeting Obesity: a new perspective from the worm’s point of view. Tom Janssen, Lise Peeters, Kevin Van Calster, Nick Suetens, Liliane Schoofs.

364C. Unfolded protein response and enpl-1 depletion sensitize C. elegans to the anti-cancer drug cisplatin. Balasubramanian Natarajan, Rahul Gaur, Oskar Hemmingsson, Gautam Kao, Peter Naredi.

365A. Bacterial fatty acids influence dauer recovery. Tiffany Kaul, Ifedayo V. Ogungbe, Frank C. Schroeder, Matthew S. Gill.

366B. FGT-1 is a mammalian GLUT2-like facilitative glucose transporter in Caenorhabditis elegans. Shun Kitaoka, Anthony Morielli, Feng-Qi Zhao.

367C. Neuronal endoplasmic reticulum stress promotes dauer entry through the activation of the Unfolded Protein Response. Warakorn Kulalert, Dennis H. Kim.

368A. ATGL-1 and LID-1 : Key Players in Fasting-Induced Lipolysis in Caenorhabditis elegans. Junghyun Lee, Jinuk Kong, Ju Yeon Jang, Junho Lee, Jae Bum Kim.

369B. Absolute Quantitation of C. elegans Dafachronic Acids during Development and in Daf Mutants. Tie-Mei Li, Jie Chen, Xiangke Li, Xiao-Jun Ding, She Chen, Xiaoguang Lei, Meng-Qiu Dong.

370C. Effect of Repeated Starvation on Fat Content in C.elegans. Shinya Matsumoto, Kosuke Kato, Yasuki Matsumura, Nao Sato, Yukari Yamamoto, Akari Sawanaga.

371A. Overexpression of an orphan gene in Pristionchus pacificus causes complete inhibition of dauer formation. Melanie G. Mayer, Ralf J. Sommer.

372B. Identifying transcription factors that regulate fat metabolism and body size. Akihiro Mori, Marian Walhout.

373C. Bis (2-ethylhexyl) phthalate regulates cytochrome P450 (DAF-9) and a specific C4 methylase (STRM-1) towards dauer formation in C. elegans. S. Mukherjee, T. Paul, M. Guria, A. Nag, J. Bandyopadhyay.

374A. Using Stable Isotope Tracers to Understand the Role of Membrane Maintenance in Aging. Shaw-Wen Chen, Carissa Perez Olsen.

375B. Quantity proteome analysis of dauer by using iTRAQ in Caenorhabditis elegans. Takehiro Oshime, Yukako Toshato, Toshiya Hayano, Masahiro Ito.

376C. Comparative metabolomics reveals endogenous ligands of the nuclear hormone receptor DAF-12 regulating C. elegans development and lifespan. Parag Mahanti, Neelanjan Bose, Joshua Judkins, Axel Bethke, Joshua Wollam, Oishika Panda, Kathleen Dumas, Anna Zimmerman, Patrick Hu, Adam Antebi, Frank Schroeder.

377A. Identification of a diet induced signaling pathway for mitochondrial adaptation during aging. Shanshan Pang, Sean P. Curran.

378B. Nematoil - a novel secreted lipid that coats the outer surface of the dauer larva of Pristionchus pacificus. Sider Penkov, Akira Ogawa, Ulrike Pässler, Margit Gruner, Hans-Joachim Knölker, Ralf Sommer, Teymuras Kurzchalia.

379C. Isolation of N-acylethanolamine resistant mutants using a forward genetic screen for resistance to synthetic cannabinoids. Pedro R. Rodrigues, Neale Harrison, Jitendra Mishra, Thomas Bannister, Matthew S. Gill.

380A. Folate metabolism and the rescue of folate deficiency by thiamine supplementation. Jason A. Rothman, Craig W. LaMunyon.

381B. Worms as chemical masterminds: complete control with small molecules. Frank C. Schroeder.

382C. Mechanistic studies on the regulation of fat accumulation by the TOR pathway in C. elegans. Ming Sheng, Josefin Friberg, Philip McQuary, Rahul Gaur, Staffan Lundstedt, Malene Hansen, Simon Tuck.

383A. EGL-8, a phospholipase C beta homolog, is a novel regulator of dauer arrest. Hung-Jen Shih, Andrew Polzin, Kathleen J. Dumas, Stephane Flibotte, Donald G. Moerman, Patrick J. Hu.

384B. Genetic requirements of the pentose phosphate pathway for the intestinal granule formation in C. elegans. Hirohisa Shiraishi, Takato Oikawa, Maya Ishibashi, Mari Tanabe, Yumi Asanuma, Reiko Aoyama, Kenji Nishikori, Takahiro Tanji, Ayako Ohashi-Kobayashi.

385C. Overexpression, purification and characterization of C. elegans glyceraldehyde-3-phosphate dehydrogenase isozymes. Ruth L. Silimon, Derek Schwabe-Warf, Valeria S. M. Valbuena, Justin W. Spengler, Megan K. Gautier, Katherine M. Walstrom.

386A. Diet Another Day: agl-1 (glycogen debranching enzyme) embryonic lethality depends on maternal diet. Jeff Simske.

387B. Novel secreted proteases regulate systemic heme homeostasis in C. elegans. J. Sinclair, K. Meng, K. Pinter, I. Hamza.

388C. Metabolism of benzimidazole anthelmintics in Caenorhabditis elegans, and the ruminant parasite, Haemonchus contortus. Susan J. Stasiuk, Gillian MacNevin, Dae-Qyun Ro, John S. Gilleard.

389A. PAQR-2 Regulates Fatty Acid Desaturation During Cold Adaptation in C. elegans. Emma Svensk, Marcus Ståhlman, Carl-Henrik Andersson, Maja Johansson, Jan Borén, Marc Pilon.

390B. Functional analysis of the acylpyruvase FAHD1 in C. elegans. A. Taferner, H. Pircher, N. Tavernarakis, P. Jansen-Dürr.

391C. Biochemical and Genetic Analysis of Lipid Droplets in C. elegans. Tracy L. Vrablik, Vlad Petyuk, Olga Shiva, Jennifer L. Watts.

392A. Genome wide responses to methyl donor availability reveal effects on metabolic, stress response and germline function genes. Wei Ding, Michael Irwin, Malene Hansen, Amy K. Walker.

393B. New path to NAD⁺: In addition to salvage biosynthesis, NRK and de novo NAD⁺ synthesis contribute to NAD⁺ recycling in C. elegans. Wenqing Wang, Matthew R. Lynes, Wendy Hanna-Rose.

394C. natc-1 mediates stress resistance and dauer formation as a downstream effector of the insulin/IGF-1 signaling pathway. Kurt Warnhoff, John T. Murphy, Daniel L. Schneider, Michelle Peterson, Simon Hsu, Kerry Kornfeld.

395A. Screening receptor guanylyl cyclase genes for roles in fat regulation in C. elegans. Emily Witham, Supriya Srinivasan.

396B. ATGL-1 requires CGI-58 to Localize to Lipid Droplets Where it Controls Droplet Morphology by Regulating Lipid Exchange and Hydrolysis. Meng Xie, Richard Roy.

397C. Development of a Global-scale Metabolic Network Model of C. elegans. Lutfu S. Yilmaz, Albertha J. Walhout.

398A. Investigating the role of neuropeptides in regulating body fat levels in C. elegans. Yorke Zhang, Supriya Srinivasan.

399B. Biological function of PUFA-derived eicosanoids in Caenorhabditis elegans. Yiwen Zhou, Jingjuan Ju, Erik Nehk, Lihong Yin, Chrisitan Steinberg, Ralph Menzel.

Physiology: Pathogenesis

400C. Neuronal serotonin signaling through G proteins negatively regulates the C. elegans immune response. Alexandra Anderson, Henry Laurenson-Schafer, Rachel McMullan.

401A. Microsporidia infection regulates ubiquitin- and chromatin remodeling-associated gene expression in the C. elegans intestine. Malina A. Bakowski, Chistopher A. Desjardins, Tiffany L. Dunbar, Christina A. Cuomo, Emily R. Troemel.

402B. Genetic architecture underlying variation in Caenorhabditis elegans host resistance to a natural pathogen. Keir M. Balla, Erik C. Andersen, Leonid Kruglyak, Emily R. Troemel.

403C. The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces mitochondrial and nuclear DNA damage in Caenorhabditis elegans. Rakesh Bodhicharla, Joel Meyer, Prasad G.L.

404A. Enhanced RNA virus susceptibility results from defects in lipid metabolism. Gina Broitman-Maduro, Saige Pompura, Stephanie Coffman, Yuanyuan Guo, Francisco Carranza, Shou-Wei Ding, Morris Maduro.

405B. Antagonistic cGMP Signaling Pathways Regulate a Heritable Developmental Response to Pathogens. Nicholas Burton, Bob Horvitz.

406C. Host-finding strategies of mammalian-parasitic nematodes. Michelle Castelletto, Ryo Okubo, Anastassia Tselikova, Elissa Hallem.

407A. Characterization of Vibrio parahaemolyticus virulence factors using Caenorhabditis elegans. Hediye N. Cinar, Surasri N. Sahu, Sungji Kim, Augusto A. Franco, Christopher Grim, Justin Hahn, Ben D. Tall, Mahendra Kothary, Atin Datta.

408B. Role of OCTR-1 expressing neurons during pathogen infection. Argenia L. Doss, Alejandro Aballay.

409C. Tissue Tropism and Infection Characterization of Novel Viruses in Caenorhabditis Nematodes. Carl J. Franz, Hilary Renshaw, Lise Frezal, Yanfang Jiang, Marie-Anne Félix, David Wang.

410A. Caenorhabditis elegans as a Model to Study Parasite-Induced Alterations in Host and Gut Microbiota Interaction. Teklu Gerbaba, Xin Wang, Kevin Rioux, Dave Hansen, Andre Buret.

411B. A key role of mitochondrial dynamics, cytochrome c release and IP3R activity in muscular dystrophy. Jean Giacomotto, Nicolas Brouilly, Marie-Christine Mariol, Laurent Segalat, Kathrin Gieseler.

412C. Transcriptome analysis of ALS-associated Mutants fust-1 and tdp-1. Patrick K. Gonzales.

413A. Identification of molecular networks that modulate intestinal ilys-3 activity in response to danger signals and bacterial challenges. Maria J. Gravato-Nobre, Suzanne Jordan, Sophie Andrews, Jonathan Hodgkin.

414B. Whole genome expression analysis of C. elegans upon recovery from Salmonella enterica infection. Brian P. Head, Alejandro Aballay.

415C. Observation of Legionella pneumophila infectious cyst-like forms in the host model Caenorhabditis elegans . Jacqueline Hellinga, Ann Karen Brassinga.

416A. PTR-15/BUS-13: A patched-related protein affecting surface properties and susceptibility to multiple surface pathogens. Dave Stroud, Alexis Tchaconas, Patricia Kuwabara, Jonathan Hodgkin.

417B. Using C. elegans to identify the nematode phosphorycholine transferase. Kevin J. Jenson, Patricia M. Berninsone.

418C. Development of a reverse genetics system for a novel nematode virus. H. Jiang, D. Wang.

419A. Identification of disease-causing mechanisms and potential therapeutic targets of Hereditary Spastic Paraplegias using C. elegans. Carl Julien, Arnaud Tauffenberger, Dina Aggad, Patrick A. Dion, Guy A. Rouleau, Pierre Drapeau, J. Alex Parker.

420B. An integrative D. discoideum, C. elegans and D. rerio approach to assess developmental and reproductive toxicity. E. Kerkhof, R. Pieters, C. Lokman, A. Woollard, C. Croes, M. Teunis, R. Bosch, M. Wildwater.

421C. A C. elegans-P. aeruginosa Liquid Assay Identifies Novel Small Molecules with Anti-Infective Properties. Daniel Kirienko, Natalia Kirienko, Frederick Ausubel.

422A. Deciphering the function of the ALS/FTD causing genes TDP-43 and C09ORF72 in C.elegans. P. Kratsios, J. Kerk, A. Vidal-Gadea, J. Villarin, J. Pierce-Shimomura, O. Hobert.

423B. Shiga-like toxin 1 confers the full pathogenicity of Enterohaemorrhagic Escherichia coli and activation of the p38/MAPK pathway in Caenorhabditis elegans. Cheng-Ju Kuo, Ting-Chen Chou, Hao-Chieh Chiu, Wan-Jr Syu, Wen-Tai Chiu, Chang-Shi Chen.

424C. The canonical WNT pathway is an important regulator of C. elegans innate immunity against the pathogen staphylococcus aureus. sid ahmed LABED, Amanda WOLLENBERG, Anna ALVES, Javier IRAZOQUI.

425A. Olfactory Plasticity in Entomopathogenic Nematodes. Joon Ha Lee, Elissa Hallem.

426B. A non endosomal role for ESCRT-II proteins in neuron and muscle physiology. Emmanuel Culetto, Christophe Lefebvre, Xavier Manière, Ivan Matic, Renaud Legouis.

427C. Identification of TDP-43 modifying kinases in a C. elegans model of TDP-43 proteinopathy. Nicole Liachko, Pamela McMillan, Chris Guthrie, Thomas Bird, James Leverenz, Brian Kraemer.

428A. Searching for therapeutic compounds for Machado-Joseph disease: a C. elegans-based screening. A. Teixeira-Castro, A. Jalles, M. Araújo, A. Miranda, C. Bessa, R. Morimoto, P. Maciel.

429B. Role of natural genetic variation in the control of susceptibility to bacterial infections in Caenorhabditis elegans. Natalia Martin, Alejandro Aballay.

430C. fshr-1 provides a connection between the oxidative stress response and innate immunity in C.elegans. Elizabeth V. Miller, Jennifer R. Powell.

431A. Update: Screening Potential Anthelmintic Compounds for Novel Activity. Megan Gross, Michael Smith, Aaron Monte, Jennifer Miskowski.

432B. The discovery of intestinal intracellular microbes in the soil nematode collected from the field of the Tohoku district, northeastern Japan. Kenji Nishikori, Eisuke Kuroda, Takahiro Tanji, Hirohisa Shiraishi, Ayako Ohashi-Kobayashi.

433C. Does the C.elegans glycosylation gene bus-8 undergo translational frameshifting to generate different protein isoforms? Delia M. O'Rourke, Martin Cullen, Dave Stroud, Mark Pavlyukovskyy, Frederick A. Partridge, Jonathan Hodgkin.

434A. Pathogen induced diapause formation requires the RNAi machinery. Maria Fernanda Palominos, Lidia Verdugo, Francisco Chavez, Andrea Calixto.

435B. The Mitochondrial Unfolded Protein Response Regulates a Pathogen-Specific Innate Immune Pathway. Mark W. Pellegrino, Amrita Nargund, Cole M. Haynes.

436C. Suppressors of TDP-1 toxicity in Caenorhadbitis elegans. I. Pena-Gonzalez, CD. Link.

437A. From fungal spore adhesion to effector gene transcription. Olivier Zugasti, Shizue Omi, Guillaume Bordet, Vincent Rouger, Carole Couillault, Julien Soule, Jerome Belougne, Didier Marguet, Jonathan Ewbank, Nathalie Pujol.

438B. Functional analysis of candidate effector proteins from a natural, intracellular pathogen of C. elegans. Aaron W. Reinke, Emily Troemel.

439C. Epitope-tagging the G-Protein Coupled Receptor fshr-1. Joseph D. Robinson, Jennifer R. Powell.

440A. On methane seeps, worms, and parasitic fungi: microsporidia-infected nematodes reveal another secret of the deep sea. Amir Sapir, Adler Dillman, Benjamin Grupe, Jeroen Ingels, Stephanie Connon, Manuel Mundo-Ocampo, John DeModena, Lisa Levin, James Baldwin, Victoria Orphan, Paul W. Sternberg.

441B. A C. elegans genome-wide RNAi screen identifies modifiers of mutant TDP-43. Aleen Saxton, Nicole Liachko, Brian Kraemer.

442C. Developing Heterorhabditis nematodes as an experimental system for the study of mutualistic symbiosis. Hillel Schwartz, Paul Sternberg.

443A. Key residues of Cry5B structure and function: Mutagenesis by alanine scanning. Jillian Sesar, Yan Hu, Hui Fan, Partho Ghosh, Raffi Aroian.

444B. PUFA therapy ameliorates Parkinson disease like symptoms. Shashikumar Shivaiah, Rajanikant Golgodu Krishnamurty.

445C. Antimicrobial compound screens using C. elegans model system for periodontal pathogens -. Shahid S. Siddiqui, Fathy A. Faskhani, Mohammad Al-Beyari.

446A. Using Caenorhabditis elegans to investigate the genetic and mechanistic basis of cellular defense against bacterial pore-forming proteins. Anand Sitaram, Raffi Aroian.

447B. C. elegans and mammalian cell cultures: comparison of two different approaches to toxicological screening of silver nanoparticles. C. Soria, T. Coccini, S. Giorgetti, L. Marchese, I. Zorzoli, U. De Simone, V. Bellotti, M. Stoppini, L. Manzo.

448C. C. elegans expressing human β2-microglobulin: a novel model for studying the amyloid toxicity. C. Soria, L. Diomede, M. Romeo, S. Giorgetti, L. Marchese, PP. Mangione, I. Zorzoli, F. Romano, S. Ramat, M. Salmona, V. Bellotti, M. Stoppini.

449A. Toxicity of the fungal lectin CCL2 against C. elegans. K. Stutz, A. Butschi, S. Bleuler-Martínez, T. Wohlschlager, M. Aebi, M. Künzler, M. Hengartner.

450B. Interplay of host and pathogen genetics upon RNA virus infection in C. elegans. Melanie Tanguy, Peter Sarkies, Jeremie Le Pen, Eric A. Miska.

451C. Role of wild-type ataxin-3 and valosin-containing protein/p97 in Machado-Joseph disease: a study in C. elegans. A. Teixeira-Castro, H. Brignull, D. Ribeiro, R. Morimoto, P. Maciel.

452A. Potential Roles of Peroxidases in C. elegans Innate Immunity. George R. Tiller, Danielle A. Garsin.

453B. The ABC transporter MRP-7 inhibits methylmercury-induced whole animal and dopamine neuron pathology. Natalia VanDuyn, Richard Nass.

454C. HLH-30/CeTFEB plays a central role in host defense against bacterial infection. Orane Visvikis, Nnamdi Ihuegbu, Anna-Maria Alves, Lyly Luhachack, Amanda Wollenberg, Gary Stormo, Javier Irazoqui.

455A. Genetic basis underlying differential susceptibility to bacteria in Caenorhabditis elegans. Ziyi Wang, Michael Herman, L. Basten Snoek, Jan Kammenga.

456B. Acyl-CoA synthase-3 and the nuclear receptor NHR-25 regulate innate immunity genes and promote pathogen resistance. Jordan D. Ward, Carol Couillault, Brendan Mullaney, Benjamin Schiller, Teresita Bernal, Sarah Petnic, Marc Van Gilst, Kaveh Ashrafi, Jonathan Ewbank, Keith Yamamoto.

457C. A unique Stenotrophomonas maltophilia strain that evades a major Caenorhabditis elegans defense pathway. Corin Vashoun White, Brian Darby, Michael Herman.

458A. The effects of bacteria from rotting fruit on C. elegans gene expression and lifespan. Amanda C. Wollenberg, Marie-Anne Félix, Javier E. Irazoqui.

459B. Enterococcus infection of C. elegans as a model of innate immunity. Grace J. Yuen, Frederick M. Ausubel.

460C. Effects of Diphenyl Diselenide on transgenic Caernohabiditis elegans Alzheimer’s disease model. D. C. Zamberlan, L. P. Arantes, J. B. T. Rocha, F. A. A. Soares.

461A. UNC-119 interacts with ARL-13 and plays a role in ciliogenesis. Qing Zhang, Qing Wei, Yuxia Zhang, Jinghua Hu.

Neurobiology: Neuronal Development

462B. CED-10 Rac signaling pathway regulates axon regeneration via JNK MAPK pathway. Tanimul Alam, Kazuya Hirose, Strahil Pastuhov, Naoki Hisamoto, Kunihiro Matsumoto.

463C. The atypical Rho GTPase CHW-1 works downstream of SAX-3/Robo to mediate axon guidance in Caenorhabditis elegans. Jamie K. Alan, Erik L. Lundquist.

464A. Postmitotic diversification of olfactory neuron types is mediated by differential activities of the HMG-box transcription factor SOX-2. Amel Alqadah, Yi-Wen Hsieh, Berta Vidal Iglesias, Chieh Chang, Oliver Hobert, Chiou-Fen Chuang.

465B. An Investigation into the Affect of Neuronal Activity on Proper Neural Connectivity in C. elegans. Kristine E. Andersen, Benjamin Barsi-Rhyne, Kristine Miller, Christopher Vargas, Joori Park, Emma Holdrich, Miri VanHoven.

466C. Dendritic arborization in dauer IL2 neurons: Genetic and bioinformatic analyses. Rebecca J. Androwski, Alina Rashid, Tom Ritter, Nathan E. Schroeder, Maureen M. Barr.

467A. Candidate modulators of tubulin and microtubule dynamics during C. elegans neural development. Renee A. Baran, Hyun S. Kim, Evan Choate, Mealani Kaiser.

468B. PLR-1, a novel E3 ligase, controls cell polarity and axonal extensions in C. elegans. Jaffar M. Bhat, Jie Pan, Harald Hutter.

469C. Gαq mediates effects of antipsychotic drugs on C. elegans developmental delay/lethality. Limin Hao, Afsaneh Sheikholfslami, Kristin Harrington, Bruce Cohen, Edgar Buttner.

470A. Mechanisms of age-related decline in axon regeneration. Alexandra Byrne, Trent Walradt, Austin Hubbert, Marc Hammarlund.

471B. Mechanisms of VD motor neuron differentiation: UNC-55 expression and repression is determined by isoforms of UNC-62. R. Campbell, W. Walthall.

472C. A role for muscle-skin interactions in shaping PVD sensory dendrites. Kevin Celestrin, Hannes Buelow, Zaven Kaprielian.

473A. Microtubules-Based Inhibition of RhoA and MAPK Signaling Promotes Synapse Maturation and Axon Branch Maintenance in C. elegans. Chun-Hao Chen, Yu-Hsien Lee, Chun-Liang Pan.

474B. Asymmetric Hox Expression by Two Opposing Wnt Signals Drives C. elegans Neuroblast Migration through Differential Cell Polarization. Chung-Kuan Chen, Gian Garriga, Chun-Liang Pan.

475C. Autonomous and nonautonomous regulation of Wnt-mediated neuronal polarity by the C. elegans Ror kinase CAM-1. Shih-Chieh Chien, Mark Gurling, Gian Garriga.

476A. Multi-layers of molecular mechanisms govern dendritic arborization in neurons. H. Chiu, Y. Zou, T. Ferreira, C.-F. Chuang, C. Chang.

477B. Neuronal fusion induced by unc-70/β-spectrin dependent axonal injury requires components important for clearance of apoptotic cells. Sean Coakley, Brent Neumann, Hengwen Yang, Ding Xue, Massimo Hilliard.

478C. Characterization of nde-5, a newly identified mutant displaying axon guidance and sprouting defects. Zhao Hua Ding, Cristina Slatculescu, Antonio Colavita.

479A. Early neural specification and the regulation of asymmetric neurogenesis in the C-lineage. Terry J. Felton, Solayr Layton-Thomas, Richard J. Poole.

480B. UNC-68/RyR channels modulate critical sub-cellular calcium signals during normal and optogenetically enhanced neuronal regeneration. Lin Sun, James Shay, Samuel Chung, Christopher Clark, Mark Alkema, Christopher V. Gabel.

481C. Lesion conditioned regeneration of C. elegans amphid sensory neurons is mediated through a reduction of sensory signaling and does not require DLK-1. Samuel H. Chung, Christopher V. Gabel.

482A. Menorah-menorah auto-fusion as a mechanism of PVD response to injury. Tamar Gattegno, Meital Oren, Benjamin Podbilewicz.

483B. Development and Function of RIS, a Caenorhabditis elegans GABAergic interneuron. Marie Gendrel, Oliver Hobert.

484C. Studying membrane fusion during development and maintenance of C. elegans neurons. R. Giordano-Santini, M. A. Hilliard.

485A. A transcriptional network controlling reciprocal homeotic transformations of ALM and BDU neurons. P. Gordon, O. Hobert.

486B. EGL-13/SoxD Specifies Distinct O₂ and CO₂ Sensory Neuron Fates. Jakob Gramstrup Petersen, Teresa Rojo Romanos, Vaida Juozaityte, Alba Redo Riveiro, Ingrid Hums, Lisa Traunmüller, Manuel Zimmer, Roger Pocock.

487C. How to Fix a Broken Neuron. Julie E. Grimm, Meital Oren, Benjamin Podbilewicz.

488A. Neuronal microtubule organization in C. elegans. Martin Harterink, Bart de Haan, Sander van den Heuvel, Casper Hoogenraad.

489B. Excluding membrane proteins from the cilia: A role for UNC-101 and LRK-1. A. Holmes, M. Doll, A. Gartner.

490C. A paired-like homeodomain protein UNC-42 specifies the SAA neuron fate in C. elegans. Myeongjin Hong, Leesun Ryu, Chris Li, Kyuhyung Kim.

491A. tld-1 regulates the synaptic localization of the TIR-1 Ca²⁺ signaling scaffold protein in left-right neuronal asymmetry. Yi-Wen Hsieh, Chieh Chang, Chiou-Fen Chuang.

492B. Coordination of small GTPase Arls in cilia signaling in C.elegans. Zeng Hu, Yujie Li, Yuxia Zhang, Qing Zhang, Jinghua Hu.

493C. UNC-116/KHC Acts with UNC-6/Netrin and UNC-40/DCC to Maintain Sensory Neuron Position in Caenorhabditis elegans. Ben Barsi-Rhyne, Kristine Miller, Christopher Vargas, Anthony Thomas, Joori Park, Martina Bremer, Jessica Jarecki, Miri VanHoven.

494A. Transcriptome analysis reveals genes regulated by MAB-5/Hox in posterior migration of Q neuroblast descendants. Matthew P. Josephson, Joel Tamayo, Mahekta Gujar, Stuart Macdonald, Erik Lundquist.

495B. Patterning of sexually dimorphic neurogenesis in the ventral nerve cord by HOM-C/Hox and TALE homeodomain transcription factors. Andrea K. Kalis, Djem Kissiov, Breanna Tetreault, Emily Kolenbrander, Jennifer Ross Wolff.

496C. Region-specific control of ventral cord neuron fate revealed by lin-39(ccc16). Andrea K. Kalis, Maria Carson Sterrett, Jennifer Ross Wolff.

497A. Non-autonomous regulation of neuronal migration by Insulin signaling, DAF-16/FOXO and PAK-1. Lisa Kennedy, Steven Pham, Alla Grishok.

498B. Regulation of unc-3, the Terminal Selector Gene of Cholinergic Motor Neurons. Sy Kerk, P. Kratsios, Oliver Hobert.

499C. Specification of SMB motor neuron fate by the C. elegans LIM homeobox protein LIM-4. Jinmahn Kim, Jihye Yeon, Chris Li, Kyuhyung Kim.

500A. Dissecting the role of CEBP-1 in axon regeneration. Kyung Won Kim, Phoenix Ying, Thijs Koorman, Mike Boxem, Yishi Jin.

501B. Characterizing Ca²⁺ dynamics in the M4 neuron using GCaMP3. Alena Kozlova, Sana Hussain, Peter Okkema.

502C. Diversification of motor neuron differentiation programs through a network of evolutionarily conserved transcription factors. P. Kratsios, J. Kerk, R. Mourao, O. Hobert.

503A. The effects of aging on dendritic plasticity and PVD-FLP branch coexistence. V. Kravtsov, M. Oren-Suissa, B. Podbilewicz.

504B. kin-20 is required for maintenance of neuronal architecture. M. LaBella, R. Rawson, C. Frøkjær-Jensen, N. Jorgensen, MW Davis, M. Bastiani, EM Jorgensen.

505C. A screen for regulators of anterior-posterior axon outgrowth in C. elegans identifies the DNC-1/p150^Glued subunit. Vi Leitenberger, Angela Lee, Brian Ackley.

506A. A Neuron from Mesoderm: A Likely Case of in vivo Neuronal Reprogramming. Shuo Luo, Bob Horvitz.

507B. The C. elegans Microtubule Minus-end Capping Homolog, PTRN-1, Stabilizes Synapses and Neurites. Jana Dorfman Marcette, Jessica Jie Chen, Michael Nonet.

508C. Role of the histone demethylase RBR-2 in neuronal development. Luca Mariani, Julien Vandamme, Anna Elisabetta Salcini.

509A. A forward genetic screen identifies modifiers of a voltage- and Ca²⁺-activated K⁺ channel in left-right neuronal asymmetry. Grethel Millington, Chieh Chang, Chiou-Fen Chuang.

510B. Neuropeptides in neuronal development, maintenance and regeneration. Ellen Meelkop, Massimo A. Hilliard.

511C. Developing a cell contact sensor for tracking neuron-glia interactions in vivo. Karolina Mizeracka, Maxwell Heiman.

512A. Local and global inhibitory cues define the stereotyped synaptic tiling in C. elegans. Kota Mizumoto, Kang Shen.

513B. Genes Needed for Neuronal Ensheathment. Emalick Njie, Daniel Cabrera, Brian Colbitz, Xiaoyin Chen, Martin Chalfie.

514C. A Neomorphic Mutation of mec-12/alpha-Tubulin Redirects Synaptic Vesicle Transport in C. elegans by Enhancing Dynein Activity. Jiun-Min Hsu, Chun-Hao Chen, Yen-Chih Chen, Kent McDonald, Mark Gurling, Albert Lee, Gian Garriga, Chun-Liang Pan.

515A. Endocannabinoid AEA as injury signal in axon regeneration. Strahil Iv Pastuhov, Naoki Hisamoto, Kunihiro Matsumoto.

516B. Characterization of the VC class motor neurons in Caenorhabditis elegans: molecular mechanisms required for their differentiation. Laura Pereira, Oliver Hobert.

517C. Genetic analysis of cholinergic synaptogenesis in Caenorhabditis elegans. Marie Pierron, Bérangère Pinan-Lucarré, Jean-Louis Bessereau.

518A. CEH-28 activates dbl-1 expression and signaling in the M4 pharyngeal neuron. Kalpana Ramakrishnan, Paramita Ray, Peter Okkema.

519B. KPC-1 protease activity regulates dendritic arborization. Nelson J. Ramirez, Yehuda Salzberg, Julius Fredens, Niels Færgeman, Hannes Buelow.

520C. Neuron-glia communication in the assembly of the C. elegans nerve ring. Georgia Rapti, Shai Shaham.

521A. Cutting Edge: Expression and function of KPC-1/furin in C. elegans. A. Rashid, R. Androwski, N. Schroeder, M. Barr.

522B. The role of the C. elegans Shugoshin homolog in sensory neurons. Bryn Ready, Tiffany Timbers, Kunal Baxi, Michel Leroux, Carlos Carvalho.

523C. egl-46 is a novel BAG cell fate modulator. Alba Redo Riveiro, Roger Pocock.

524A. Hunting for new genes that function in neuronal maintenance. James Ritch, Avery Fisher, Andrea Thackeray, Claire Benard.

525B. Neurobehavioral defects in a C. elegans mutant for an intellectual disability-associated gene. Ana-Joao Rodrigues, Carlos Bessa, Filipe Marques, Bruno Vasconcelos, Filipa Pereira, Adriana Miranda, Patrícia Maciel.

526C. Deciphering the molecular mechanisms that regulate the specification of O₂ and CO₂ sensing neurons. Teresa Rojo Romanos, Jakob Gramstrup Petersen, Roger Pocock.

527A. Modular control of glutamatergic neuronal identity in C. elegans by distinct homeodomain proteins. Esther Serrano Saiz, Richard J. Poole, Felton Terry, Hobert Oliver.

528B. Methods for Studying Nerve Ring Assembly in C. elegans. Anupriya Singhal, Peter Insley, Shai Shaham.

529C. Regulation of sensory neuron architecture. Aakanksha Singhvi, Christine Friedman, Shai Shaham.

530A. Regulatory logic of pan-neuronal gene expression. Inés Carrera, Nikolaos Stefanakis, Oliver Hobert.

531B. The CDH-4 Fat-like cadherin is required for anterior-posterior Q neuroblast migrations. Lakshmi Sundararajan, Erik Lundquist.

532C. A PCP-like pathway acts to position or properly space (tile) embryonic motor neurons along the ventral nerve cord. M. Tanner, A. Ghadban, C. Slatculescu, B. Huang, T. Perkins, A. Colavita.

533A. Transmembrane Collagen COL-99 is Involved in Axon Guidance Along Major Longitudinal Axon Tracts and Ventral Nerve Cord Asymmetry in C. elegans. Thomas Unsoeld, Jesse Taylor, Harald Hutter.

534B. Mutations in C9ORF72/F18A1.6 produce developmental and behavioral defects. Xin Wang, Edgar Buttner.

535C. Investigation of a novel transition fiber component DYF-20 in C.elegans. Qing Wei, Jinghua Hu.

536A. Transition fibers protein DYF-19 regulates the ciliary entry of assembled IFT complex. Qing Wei, Qingwen Xu, Kun Ling, Jinghua Hu.

537B. The SWI/SNF chromatin remodeling complex selectively affects multiple aspects of serotonergic neuron differentiation. Peter J. Weinberg, Nuria Flames, Hitoshi Sawa, Gian Garriga, Oliver Hobert.

538C. Developmental Specification of a Polymodal Nociceptor in C. elegans. Jordan Wood, Denise Ferkey.

539A. SYD-1 mediates ventral axon guidance in the HSN neuron of C. elegans. Yan Xu, Christopher Quinn.

540B. Understanding cellular mechanisms of selective fasciculation between dendrites. Candice Yip, Maxwell Heiman.

541C. Dendrite tiling as an emergent property of self-avoidance. Candice Yip, Maxwell Heiman.

542A. Suppression of microtubules dynamics by DHC-1 is required for an intact cytoskeleton and efficient cargo trafficking in C. elegans dendrites. Shaul Yogev, Kang Shen.

543B. Identification of APL-1 as a long-range or short-range signaling molecule in C. elegans . Pei Zhao, Chris Li.

544C. Genetic basis of subtype diversification of Touch Receptor Neurons in C. elegans. Chaogu Zheng, Margarete Diaz Cuadros, Martin Chalfie.

Neurobiology: Synaptic Function and Circuits

545A. Sink or Swim: Identifying Novel Regulators of Presynaptic Dopamine Signaling. Sarah Baas, J. Andrew Hardaway, Shannon Hardie, Sarah Whitaker, Tessa Popay, Phyllis Freeman, Randy Blakely.

546B. Understanding the function of Cell Adhesion molecules in the C. elegans nervous system. Pratima Sharma, Ashwani Bhardwaj, Pallavi Sharma, Vina Tikiyani, Shruti Thapliyal, Nagesh Kadam, Kavita Babu.

547C. Unraveling mechanisms for the establishment of synaptic connectivity in a simple neural circuit. B. Barbagallo, M. Francis.

548A. Understanding the mechanism of environmental stress induced nervous system plasticity. Abhishek Bhattacharya, Oliver Hobert.

549B. Serotonergic/Peptidergic Cotransmission in the C. elegans Egg-Laying Circuit. Jacob Brewer, Michael Koelle.

550C. Multiple dopamine signaling pathways antagonize RhoA signaling in the nervous system. Kimberley H. R. Bryon-Dodd, Clara Essmann, Andrew Porter, Rachel McMullan, Stephen Nurrish.

551A. Amphetamine and β-Phenylethylamine Activate an Amine-Gated Chloride Channel. Bryan Safratowich, Chee Lor, Laura Bianchi, Lucia Carvelli.

552B. Redundant mechanisms for modulation of the serotonergic HSNs by an environmental cue. Jung-Hwan Choi, Niels Ringstad.

553C. Understanding how neurotransmitter signaling drives two-state activity of the C. elegans egg-laying behavior circuit. Kevin M. Collins, Michael R. Koelle.

554A. Screening for Suppressors of Excitotoxic Neurodegeneration in C. elegans: Using Nematode Genetics to Understand the Process of Neurodegeneration in Brain Ischemia. Anthony O. Edokpolo, Itzhak Mano.

555B. VAV-1 acts cell autonomously to regulate cholinergic motor neuron presynaptic activity. A. Fry, J. Laboy, K. Norman.

556C. The AP2 clathrin adaptor subunit APM-2 regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans. Steven D. Garafalo, Caroline L. Dahlberg, Emily Malkin, Peter Juo.

557A. Analysis of optogenetically evoked motor neuron activity by Ca²⁺ imaging using RCaMP in muscle. Sebastian Wabnig, Caspar Glock, Cornelia Schmitt, Alexander Gottschalk.

558B. Changes in Cellular Circuits for Chemosensation during Development May Underlie Maturation of Chemotaxis Behavior. Laura A. Hale, Sreekanth H. Chalasani.

559C. The C2A domain of synaptotagmin-1 drives synaptic vesicle fusion and endocytosis. Robert J. Hobson, Eric G. Bend, Shigeki Watanabe, Erik M. Jorgensen.

560A. The UNC-73/Trio Sec14 Domain Localizes to a Subcellular Compartment in C. elegans Neurons. Daniel Hoffman, Alyssa Hoop, Robert Steven.

561B. Combination of optogenetics and reverse genetics: novel behavior screening for regulators of neural differentiation. S. Hori, S. Oda, Y. Suehiro, Y. Iino, S. Mitani.

562C. Worm migraines: Characterization of a Gain-of-Function Mutation in the Voltage-Gated Calcium Channel, UNC-2/Ca_V2. Yung-Chi Huang, Jennifer K. Pirri, Diego Rayes, Yasunori Saheki, Cornelia I. Bargmann, Michael M. Francis, Mark J. Alkema.

563A. Regeneration of synaptic vesicles from large endocytic vesicles. Edward J. Hujber, Shigeki Watanabe, M. Wayne Davis, Erik M. Jorgensen.

564B. Mechanisms of C. elegans locomotion speed control during oxygen-chemotaxis. Ingrid M. Hums, Fanny Mende, Lisa Traunmüller, Michael Sonntag, Manuel Zimmer.

565C. VPS-39 promotes synaptic vesicle fusion in C. elegans. Susan M. Klosterman, Szi-chieh Yu, Anna O. Burdina, Janet E. Richmond.

566A. Single Cell Mass Spectrometry of Neuropeptides in Ascaris suum Motor Neurons. Christopher J. Konop, Jenny Knickelbine, Molly Seygulla, Martha Vestling, Antony O. W. Stretton.

567B. The Anaphase-Promoting Complex Regulates GABA Transmission at the C. elegans Neuromuscular Junction. Jennifer R. Kowalski, Hitesh Dube, Denis Touroutine, Patricia R. Goodwin, Marc Carozza, Zachary Didier, Michael M. Francis, Peter Juo.

568C. Ca²⁺ dynamics of a whole single neuron. Sayuri Kuge, Takayuki Teramoto, Takeshi Ishihara.

569A. Maintaining sensitivity: dissecting sensory adaptation using high-throughput in vivo calcium imaging. Johannes Larsch, Dirk R. Albrecht, Cori I. Bargmann.

570B. Pattern generation in the locomotory system by optogenetic stimulation of command neurons and sensory neurons. J. Liewald, C. Schmitt, S. Wabnig, C. Glock, J. Akerboom, L. Looger, N. Pokala, C. Bargmann, E. Ardiel, C. Rankin, A. Gottschalk.

571C. Postsynaptic current bursts instruct action potential firing at a graded synapse. Ping Liu, Bojun Chen, Zhao-Wen Wang.

572A. Multiple innexins contribute to electrical coupling of C. elegans body-wall muscle. Ping Liu, Bojun Chen, Zeynep Altun, Maegan Gross, Alan Shan, Benjamin Schuman, David Hall, Zhao-Wen Wang.

573B. Regulation of the nicotinic acetylcholine receptor ACR-16. Ashley A. Martin, Feyza Sancar, Janet E. Richmond.

574C. Chemical tuning of CO2-responsive BAG neurons. Ewan St. John Smith, Luis Antonio Martinez-Velazquez, Niels Ringstad.

575A. The DAF-7/TGF-β signaling pathway regulates abundance of the glutamate receptor GLR-1. Annette McGehee, Benjamin Moss, Peter Juo.

576B. Locating synaptic calcium channels. Sean Merrill, S. Watanabe, J. R. Richards, C. Frøkjær-Jensen, E. M. Jorgensen.

577C. A Novel UNC-43 (CaM Kinase II) Dense Core Vesicle Trafficking Pathway Blocks UNC-31 (CAPS) - Dependent Secretion from Neuronal Cell Somas. Christopher Hoover, Stacey Edwards, Szi-chieh Yu, Maike Kittelmann, Stefan Eimer, Janet Richmond, Kenneth Miller.

578A. Does Cysteine String Protein contribute to C. elegans Nervous System Function? Ben Mulcahy, Paul Ibbett, Lindy Holden-Dye, Vincent O'Connor.

579B. Age-dependent changes at the C. elegans neuromuscular junction. Ben Mulcahy, Lindy Holden-Dye, Vincent O'Connor.

580C. A role for miRNA machinery at the neuromuscular junction? Patrick J. O'Hern, Anne Hart.

581A. An unconventional role of a conserved sterol biosynthetic protein ERG-28 in SLO-1 function. Kelly H. Oh, Hongkyun Kim.

582B. The molecular mechanisms of behavioral sexual dimorphism. Meital Oren, Oliver Hobert.

583C. Syntaxin Habc domain is required for synaptic function. Leonardo Parra, Jenna Whippen, Catherine Dy, Erik Jorgensen.

584A. Sexually dimorphic synaptic connectivity in the C. elegans tail. Matthew Johnson, Deborah Ryan, Douglas Portman.

585B. unc-17 suppressors and subway crowding. Jim Rand, Ellie Mathews, Greg Mullen.

586C. Regulating Rho and neurotransmitter release. K. R. Ryan, S. J. Nurrish.

587A. A circuit for decision making in C. elegans: a computational approach. Tom Sanders, Gert Jansen, Netta Cohen.

588B. The computational role of the head navigation circuit in C. elegans: Exploring the interneuron layer in silico. Tom Sanders, Netta Cohen.

589C. lgc-40 Encodes a Choline-Gated Chloride Channel Subunit Expressed in Neurons and Muscles. Steve Sando, Bob Horvitz.

590A. A gustatory neural circuit for salt concentration memory in Caenorhabditis elegans. H. Sato, H. Kunitomo, S. Oda, Y. Iino.

591B. Understanding the auto-receptor component of the DOP-2 signal transduction pathway in modulating dopamine release. Jatinder Singh, Roderick King, Crystal Clark, Ping Han, Singh Harbinder.

592C. Notch signaling regulates synaptic transmission at the C. elegans neuromuscular junction. Altar Sorkac, Michael DiIorio, Hannah Graham, Komudi Singh, Anne Hart.

593A. Role of serotonin signaling in C. elegans fat metabolism. T. Noble, S. Srinivasan.

594B. Integration of Sensory Perception, Lipid Metabolism and Food Intake in C. elegans. J. Stieglitz, S. Srinivasan.

595C. Dopamine regulates acetylcholine signaling and body size via octopamine and CREB signaling in C. elegans. Satoshi Suo, Eitaro Oami, Midori Yoshida, Shoichi Ishiura.

596A. Neuropeptides Function in a Homeostatic Manner to Modulate Excitation-Inhibition Imbalance in C. elegans. Seika Takayanagi-Kiya, Tamara M. Stawicki, Keming Zhou, Yishi Jin.

597B. 4-D Ca²⁺ imaging of the multiple neurons in a local circuit regulating behavioral choice. Takayuki Teramoto, Yuta Yamamoto, Takeshi Ishihara.

598C. Neurexin and Neuroligin Mediate Retrograde Synaptic Inhibition in C. elegans. Zhitao Hu, Sabrina Hom, Tambudzai Kudze, Xiajing Tong, Seungwon Choi, Gayane Aramuni, Weiqi Zhang, Joshua Kaplan.

599A. Identifying molecules involved in dense-core vesicle biology. Irini Topalidou, Brooke Jarvie, Jill Hoyt, Michelle Giarmarco, Angela L. Barr, Michael Ailion.

600B. A computational model of the intracellular signaling pathway for odor receptor neuron in C. elegans. Mamoru Usuyama, Yuishi Iwasaki, Chisato Ushida, Ryuzo Shingai.

601C. A Genetic Resource for Assaying Neuropeptide Function in vivo. Amy B. Vashlishan Murray, Edward Pym, Joshua Kaplan.

602A. Does local protein synthesis in the sensory dendrites of the AFD thermosensory neuron play a role in long-term memory? V. Venkatachalam, S. Yogev, J. Calarco, A. Calvo, J. Hawk, M. Klein, D. Colon-Ramos, K. Shen, A. Samuel.

603B. Track-A-Worm, an open-source system for quantitative assessment of C. elegans locomotory and bending behaviors. Sijie Wang, Zhao-Wen Wang.

604C. DAF-19 acts as a negative regulator to modulate environment-dependent GABA phenotypes. Yusu Xie, Mustapha Moussaif, Ji Ying Sze.

605A. A role for T-type calcium channels in serotonin signaling. Kara Zang, Niels Ringstad.

Neurobiology: Behavior

606B. The Pristionchus pacificus obi-3 mutant lacks attraction to beetle host pheromone and shows increased turning frequency. Georgina Aguilar-Portillo, Jimmy Escobedo, Neomal Muthumala, Ray Hong.

607C. Insights into the molecular mechanisms of memory rewriting in Caenorhabditis elegans. Ichiro Aoki, Ikue Mori.

608A. Response to repeated activation of ASH requires glutamate, dopamine, and neuropeptide signaling. Evan L. Ardiel, Andrew C. Giles, Theodore Lindsay, Ithai Rabinowitch, William Schafer, Shawn Lockery, Catharine H. Rankin.

609B. NLP-7 peptide modulation of the egg-laying circuit. Navonil Banerjee, Raja Bhattacharya, Michael Francis.

610C. Molecular regulators of male sex-drive. Scott W. Emmons, Arantza Barrios.

611A. Conserved neuropeptidergic regulation of associative learning by vasopressin/oxytocin-related peptides. I. Beets, L. Temmerman, T. Janssen, E. Meelkop, L. Frooninckx, G. Jansen, L. Schoofs.

612B. Notch DSL ligand lag-2 is required for C. elegans lethargus quiescence. Heather L. Bennett, Huiyan Huang, Komudi Singh, Anne C. Hart.

613C. A Mutant in Another cGMP-dependent Protein Kinase, PKG-2, is defective in short and long-term odor adaptation. Eduardo Bernal, Neomal Muthumala, Ray L. Hong.

614A. Effects of mutations in the C. elegans presenilin homologue, sel-12, on tap habituation. T. Bozorgmehr, C. Rankin.

615B. The voltage-gated chloride channels encoded by clh-3 regulate the excitability of the HSN neurons. Robyn Branicky, Hiroaki Miyazaki, Kevin Strange, William R. Schafer.

616C. A quantifiably complete repertoire of C. elegans locomotion. Andre E. X. Brown, Roland Schwarz, Robyn Branicky, William Schafer.

617A. Acute odor recognition in AWC neuron of C. elegans after adaptation. Chantal Brueggemann, Damien O'Halloran, Noelle L'Etoile.

618B. The AIB interneuron is required for thermotaxis. Ana C. Calvo, Josh Hawk, Nathan Cook, Vivek Venkatachalam, Aravinthan D. T. Samuel, Daniel A. Colon-Ramos.

619C. Oxygen sensing neurons control carbon dioxide response in C. elegans. M. A. Carrillo, M. L. Guillermin, S. Rengarajan, R. Okubo, E. A. Hallem.

620A. Natural polymorphisms in HECW-1 E3 ubiquitin ligase affect C. elegans pathogen avoidance behavior. Howard Chang, Dennis Kim.

621B. Pleiotropic genes affecting touch sensitivity in C. elegans. Xiaoyin Chen, Martin Chalfie.

622C. Neuropeptides can regulate feeding behavior in the absence of MC activity. Mi Cheong Cheong, Young-Jai You, Leon Avery.

623A. Elucidation of a neuronal mechanism of nictation, a dispersal behavior, in C. elegans. Myung-kyu Choi, Harksun Lee, Daehan Lee, Dongjun Park, Junho Lee.

624B. Single-cell transcriptomic analysis identifies quiescence-inducing neuropeptides. Elly S. Chow, Erich M. Schwarz, Paul W. Sternberg.

625C. Investigating the role of polycystins in sex pheromone chemotaxis of male C. elegans. Ching-Ki Li, King-Lau Chow.

626A. SRD-1 is required for C. elegans males to respond to the Caenorhabditis remanei female sex-pheromone. Hainan Yang, Yuan Zhou, King-Lau Chow.

627B. AWC Neurons Mediate Navigation in a DC Electric Field. Steven D. Chrisman, Christopher B. Waite, Eric P. Foss, Lucinda Carnell.

628C. Dopamine down-modulates the activity of a re-current circuit via D2-like signaling during male mating. Paola Correa, Luis Rene Garcia.

629A. Uncovering the molecular basis for ethanol action on the BK channel using genetic screens. Scott Davis, Kevin Hu, Jon Pierce-Shimomura.

630B. Genetic sex alters the logic of sensory behavior. Kelli A. Fagan, Jessica R. Bennett, Frank C. Schroeder, Douglas S. Portman.

631C. HLH-17 Dependent Regulation of the Dopamine Transporter Gene, dat-1 and the Dopamine Receptor Gene, dop-3 Can Be Tied to the Oxidative Stress Response in C. elegans. Chaquettea M. Felton, Casonya Johnson.

632A. Caenorhabditis-in-Drop (CiD) method to measure worm behavior and longevity. Benjamin L. Freedman, Samy Belfer, Han-Sheng Chuan, Jinzhou Yuan, Michael Norton, Haim Bau, David Raizen.

633B. ASI regulates satiety quiescence. Thomas L. Gallagher, Leon Avery, Young-jai You.

634C. Neuropeptide modulation of C. elegans light avoidance circuitry. D. Dipon Ghosh, Michael R. Koelle, Michael N. Nitabach.

635A. Modular genetic architecture shapes individual variation in innate avoidance behavior in C. elegans. Rajarshi Ghosh, Aylia Mohammadi, William Ryu, Leonid Kruglyak.

636B. Toward the identification of behavioral strategies underlying C. elegans thermotaxis using the Multi-Worm Tracker. Andrew C. Giles, Yuki Tsukada, Shunji Nakano, Ikue Mori.

637C. The neuronal basis of food choice behavior in Caenorhabditis elegans. Brian Conroy, Maria Morabe, Lillian Haynes, Melissa Chambers, Rachel Macfarlane, Elizabeth Glater.

638A. Unbiased optogenetic circuit mapping: AVK interneurons, a case study. C. Schultheis, K. Erbguth, S. Wabnig, M. Brauner, A. Gottschalk.

639B. Monoamines amplify and focus global peptidergic signaling cascades to modulate nociceptive responses in Caenorhabditis elegans. V. Hapiak, A. Stein, W. J. Law, A. Ortega, R. W. Komuniecki.

640C. How do worms choose the right food? - Dissecting the signaling mechanisms underlying preference of food odors. Gareth Harris, Yu Shen, Heon-ick Ha, Alessandra Donato, Xiaodong Zhang, Yun Zhang.

641A. Exploring the low-dose activating effects of ethanol in C. elegans. E. G. Hawkins, J. C. Bettinger, A. G. Davies.

642B. A Common Behavioral Model Underlies the Motility of a Diverse Set of Nematodes. Stephen J. Helms, Leon Avery, Greg J. Stephens, Thomas S. Shimizu.

643C. A genetic screen for Notch downstream targets regulating C. elegans sleep. Huiyan Huang, Chen-Tsen Zhu, Anne Hart.

644A. A calcium-rich breakfast: physiological activity in C. elegans serotonergic neurons during the enhanced slowing response and upon emergence from lethargus. Shachar Iwanir, Adam Brown, Dana Najjar, Meagan Palmer, Ivy Fitzgerald, David Biron.

645B. ASE and ASH neuron sensitivities determine NaCl attraction or avoidance behaviour. Oluwatoroti Umuerri, Martijn Dekkers, Gert Jansen.

646C. Regulation of motivational states in C. elegans. Changhoon Jee, L. René Garcia.

647A. Studying the neural circuits of food choice imprinting in C. elegans. Xin Jin, Navin Pokala, Cori Bargmann.

648B. Identification of novel roles of the ETS-5 transcription factor in sensory neuron specification. Vaida Juozaityte, Roger Pocock.

649C. Pheromones regulate nematode dispersal. F. Kaplan, H. Alborn, S. von Reuss, F. Schroeder.

650A. Chemotaxis follows the nose. Rex A. Kerr.

651B. The regulation of nictation, a dispersal behavior in C. elegans, by insulin-like molecules. Nari Kim, Harksun Lee, Myung-kyu Choi, Daehan Lee, Junho Lee.

652C. Identification of regulatory factors for forgetting in C. elegans. Tomohiro Kitazono, Akitoshi Inoue, Takeshi Ishihara.

653A. The C. elegans cGMP-dependent Protein Kinase EGL-4 Regulates Nociceptive Behavioral Sensitivity. Michelle C. Krzyzanowski, Chantal Brueggemann, Meredith J. Ezak, Jordan F. Wood, Kerry L. Michaels, Christopher A. Jackson, Bi-Tzen Juang, Kimberly D. Collins, Michael C. Yu, Noelle D. L'Etoile, Denise M. Ferkey.

654B. Thermoreceptor neurons regulate the temperature-dependence of motor programs. S. Lasse, V. Y. Wang, M. B. Goodman.

655C. Food signals modulate sensory integration behavior. Hiu Lau, Sreekanth Chalasani.

656A. Analyses of C. elegans male ray neuron activity during mating. Olivia Philpot, May Boggess, Rene Garcia, Robyn Lints.

657B. A neuronal flip-flop generates random search behavior in the nematode C. elegans. W. Roberts, S. Augustine, T. Lindsay, K. Lawton, T. Thiele, N. Pokala, R. Anderson, M. Britton, C. Bargmann, S. Lockery.

658C. Different Stressors, Same Sleep: heat, cold, salt, alcohol all trigger ALA-dependent behavioral quiescence. Jessie M. Lopez, Cheryl Van Buskirk.

659A. Characterizing the hsf-1-Independent Behavioral Response to Heat Shock. Richard Mansfield, Cheryl Van Buskirk.

660B. The SWI/SNF chromatin remodeling complex modifies ethanol-responsive behaviors. L. Mathies, G. Blackwell, L. Hack, A. Adkins, T. Webb, K. Kendler, B. Riley, A. Davies, J. Bettinger.

661C. The Role of Heterotrimeric G-protein Signaling Pathways in Habituation. Andrea McEwan, Andrew Giles, Catharine Rankin.

662A. Acute Laser Dissection of Mechanosensory Circuitry in C. elegans. Pavan Mehat, Lin Sun, Samuel Chung, Christopher Gabel.

663B. Serotonergic and peptidergic signaling interact to modulate aversive behavior. Holly Mills, Amanda Ortega, Richard Komuniecki.

664C. Alkaline pH sensation mediated by GCY-14, a transmembrane guanylyl cyclase. T. Murayama, M. Fujiwara, J. Takayama, I. Maruyama.

665A. A longitudinal study of C. elegans larvae reveals a novel locomotion switch, regulated by G_αs signaling. Stanislav Nagy, Charles Wright, Nora Tramm, Nicholas Labello, Stanislav Burov, David Biron.

666B. Identification of New Genes Involved in C. elegans Thermotaxis Behavior. Shunji Nakano, Jiang Tianyu, Takamasa Suzuki, Tetsuya Higashiyama, Ikue Mori.

667C. The CMK-1 CaMKI protein integrates food signals to regulate sensory neuron state. Scott J. Neal, Kyuhyung Kim, Piali Sengupta.

668A. A new imaging system for high-throughput C. elegans analysis of temperature-entrained rhythmic gene expression. Dru Charles Nelson, Ari Winbush, Alexander van der Linden.

669B. NLP-22 is a Neuromedin S-like neuropeptide which regulates behavioral quiescence. Matthew Nelson, David Raizen.

670C. The effect of sex difference on olfactory learning in Caenorhabditis elegans. Julia Nguyen, Shane Smith*, Gareth Harris, Yun Zhang.

671A. Isoform-specific axonal translocation of a novel DAF-2 isoform regulates synaptic and behavioral plasticity. Hayao Ohno, Shinya Kato, Yasuki Naito, Hirofumi Kunitomo, Masahiro Tomioka, Yuichi Iino.

672B. Genetically imposed dietary restriction makes normally appetitive food repulsive by altering odor-sensing circuits. Birgitta Olofsson.

673C. The Role of Post-Translational Modifications in the Regulation of Serotonin Signalling. Andrew C. Olson, Michael R. Koelle.

674A. Remote Control and Observation for more meaningful Behavioral Experiments. Andy Papp, John Biondo.

675B. Genetic screens for IL2 lineage-specific regulators in Caenorhabditis elegans. Dongjun Park, Peter Swoboda, Junho Lee.

676C. Regulation of the Egg-Laying Behavioral Response to Hypoxia. Corinne Pender, Bob Horvitz.

677A. A male-specific neuropeptide, FLP-23, is necessary for sperm transfer in C. elegans. Renee Miller, Inna Hughes, Teigan Ruster, Andrew Spitzberg, Steven Husson, Tom Janssen, Liliane Schoofs, Douglas Portman.

678B. A Potential Role for Palmitoylation in the Acute Response to Ethanol. R. Raabe, A. G. Davies, J. C. Bettinger.

679C. PKC-1 mediates responses to 5-HT-dependent behavioral adaptation in C. elegans. Seth Ronk, Eric Foss, Lucinda Carnell.

680A. Internal metabolic status modulates pheromone-mediated neural plasticity in C. elegans. L. Ryu, K. Kim.

681B. Identification of molecules interacting with the insulin/PI3K pathway involved in salt chemotaxis learning. N. Sakai, M. Tomioka, T. Adachi, T. Jiang, Y. Iino.

682C. Regulation of Behavioral Suspended Animation and Mitochondrial Dynamics in Response to Oxygen Deprivation. N. Salazar-Vasquez, P. Ghose, E. C. Park, A. Tabakin, C. Rongo.

683A. The C. elegans interneuron ALA is a nociceptor. Jarred Sanders, Stanislav Nagy, Graham Fetterman, Charles Wright, David Biron.

684B. G protein coupled receptor SRTX-1 is a key component for thermosensation in AFD ensuring temperature sensation range. Hiroyuki Sasakura, Hiroko Ito, Kyogo Kobayashi, Keita Suzuki, Ikue Mori.

685C. Control of sleep-like behavior by the G-alpha(q) gene egl-30. Juliane Schwarz, Henrik Bringmann.

686A. Identifying Novel BK Channel Modulators. Luisa Scott, Sangeetha Iyer, Scott Davis, Ashley Philpo, Angela Shen, Sarah Nordquist, Jon Pierce-Shimomura.

687B. The C. elegans male regulates movement direction during mating through cholinergic control of the sex-shared command cells. Amrita Laxman Sherlekar, Abbey Janssen, Meagan Siehr, Laura Caflisch, May Boggess, Robyn Lints.

688C. Is sleep conserved? Making the case in D. melanogaster and C. elegans. Komudi Singh, Jennifer Y. Ju, Melissa B. Walsh, Michael A. DiIorio, Anne C. Hart.

689A. Expanding the Spectrum of Dopamine Regulators: Swip-10, the (m)BLAC Sheep of the Family. C. Snarrenberg, S. Whitaker, Q. Han, E. Pohl, J. A. Hardaway, R. D. Blakely.

690B. Quantitative trait loci mapping of temperature-dependent behaviour in Caenorhabditis briggsae. Gregory W. Stegeman, Asher D. Cutter, William S. Ryu.

691C. Odorant choice behavior and systematic reverse genetics approach to reveal molecular mechanisms underlying the behavior. Y. Suehiro, S. Mitani.

692A. Sensory inputs are centrally integrated to modulate nociception in Caenorhabditis elegans. Philip Summers, Amanda Ortega, Richard Komuniecki.

693B. Exploring the role of rapsyn-1 in regulating C. elegans behavior. Ada Tong, Sreekanth Chalasani.

694C. Dopaminergic control of gait switching in C. elegans. Stephen M. Topper, Sara Aguilar, Layla Young, Jonathan Pierce-Shimomura.

695A. Ethanol induces state-dependent behavioral transition. Stephen M. Topper, Sara Aguilar, Layla Young, Andres Vidal-Gadea, Jonathan Pierce-Shimomura.

696B. Identification of genes involved in the pheromone signaling that regulates olfactory plasticity. H. Toriyabe, K. Yamada, Y. Iino.

697C. Why do sleeping worms look like hockey sticks? Nora Tramm, Naomi Oppenheimer, Efraim Efrati, Stanislav Nagy, David Biron.

698A. The roles of biogenic amines on feeding state-dependent thermotactic behavior in C. elegans. Satomi Tsukamoto, Shunji Nakano, Ikue Mori.

699B. Caenorhabditis elegans can detect and avoid from rare earth ions, which have toxic effects on the worm locomotion, growth, and development. Tokumitsu Wakabayashi, Yuta Nakano, Yui Nojiri, Miwa Watanabe, Hiroshi Tomita.

700C. Small Molecule Communication: C. elegans and bacterial chemical signals. Kristen Werner, Lark Perez, Martin Semmelhack, Bonnie Bassler.

701A. The monoamine neurotransmitter serotonin shows evolutionarily divergent effects on feeding behavior in Pristionchus pacificus. Martin Wilecki, James W. Lightfoot, Ralf J. Sommer.

702B. Root-knot Nematode Behavior, Pheromones, and Genetics. Valerie Williamson, George Bruening, Jacinta Gimeno, Sylwia Fudali, Frank Schroeder.

703C. Genetic analysis of dopamine signaling for repulsive odor learning. Shuhei Yamazaki, Kotaro Kimura.

704A. A forward screen to identify genes involved in the blockage of olfactory adaptation by food in C. elegans. Amanda Cha, Ghazal Ghafari, Laine Janzen, Stephanie Summers, Pilar Stinson, Marie Engelhardt, Kelsi Kettellapper, Jamie Knight, Noelle L'Etoile, Jared Young.

705B. Investigating the neural mechanisms underlying a hypertonic response in Caenorhabditis elegans. Jingyi Yu, Yun Zhang.

Neurobiology: Systems Neurobiology

706C. Neurotoxic unc-8 mutants encode constitutively active DEG/ENaC channels that are blocked by divalent cations. Ying Wang, Lu Han, Cristina Matthewman, Tyne Miller, David Miller, Laura Bianchi.

707A. A circuit for working memory in C. elegans. Adam Calhoun, Tatyana Sharpee, Sreekanth Chalasani.

708B. Protein with tau-like repeats regulates neuronal integrity and lifespan in C. elegans.. Yee Lian Chew, Xiaochen Fan, Jürgen Götz, Hannah Nicholas.

709C. Regulation of Coincident Activity is an Efficient Strategy for Reversible Modulation of Arousal in C. elegans Sleep. Julie Cho, Paul Sternberg.

710A. In vivo optical recording of action potentials in C. elegans body wall muscles using the voltage sensitive fluorescent protein ArcLight. Liping He, Julian Wooltorton, Brian Salzberg, Chris Fang-Yen.

711B. Transport mechanisms involved in pH regulation of C. elegans amphid sheath glia. Jeff Grant, Rachele Sangaletti, Laura Bianchi.

712C. Imaging the brain. Wafa Amir, Nicholas Swierczek, Rex A. Kerr.

713A. Temperature experience-inducing cold tolerance is regulated by insulin signaling in intestine and neuron. Akane Ohta, Satoru Sonoda, Tomoyo Ujisawa, Yuko Kobayashi, Hayato Nakamoto, Atsushi Kuhara.

714B. Mechanosensitive innexin channels in C. elegans touch neurons. R. Sangaletti, L. Bianchi.

715C. A Genome Wide Analysis of Na⁺/Ca²⁺ Exchanger Genes in C. elegans. Vishal Sharma, Chao He, Julian Sacca-Schaeffer, Eric Brzozowski, Damien O'Halloran.

716A. Isolating genes for temperature experience-dependent cold tolerance. Satoru Sonoda, Yukari Kinoshita, Shoko Furukawa, Mikiko Endo, Yushuke Uehara, Akane Ohta, Atsushi Kuhara.

717B. A single neuron class with contrasting sensory tuning curves enables sex-specific attraction in C. elegans. Jagan Srinivasan, Anusha Narayan, Omer Durak, Neelanjan Bose, Frank C. Schroeder, Paul W. Sternberg.

718C. Screening a Million Mutations to Identify Novel Ciliary Proteins. Tiffany A. Timbers, Victor L. Jensen, Katherine Lee, Stephanie Garland, Mark Edgley, Donald G. Moerman, Michel R. Leroux.

719A. System identification for thermosensory neuron encoding thermal environment. Y. Tsukada, N. Honda, A. Murase, T. Shimowada, O. Noriyuki, A. Kuhara, S. Ishii, I. Mori.

720B. Photo and pheromone sensoryneuron regulates temperature experience-dependent cold tolerance. Tomoyo Ujisawa, Satoru Sonoda, Tomohiro Ishiwari, Akane Ohta, Atsushi Kuhara.

721C. BBS-4 and BBS-5 function redundantly to regulate IFT recycling in cilia. Yuxia Zhang, Qingwen Xu, Yan Hang, Qing Wei, Qing Zhang, Yujie Li, Zeng Hu, Kun Ling, Jinghua Hu.

Development and Evolution: Cell Fate Patterning (Embryonic and Postembryonic)

722A. Identification and characterisation of novel genes involved in the development of the C. elegans stem-like seam cells. Peter J. Appleford, Alison Woollard.

723B. Systematic quantification of developmental phenotypes at single-cell resolution during embryogenesis. Julia Moore, Zhuo Du, Zhirong Bao.

724C. Robustness of the vulval cell fate pattern to pathway dosage modulation and cryptic evolution of lin-3 regulatory sequences. Michalis Barkoulas, Alexandre Peluffo, Marie-Anne Félix.

725A. Exploring the genetic regulation of a stochastic cell decision using Mutation Accumulation lines in C. elegans and C. briggsae. Fabrice BESNARD, Marie-Anne Félix.

726B. Environmental flexibility of C. elegans vulval signalling pathways. Stephanie Grimbert, Christian Braendle.

727C. Muscles from Ectoderm: Possible Cases of in vivo Reprogramming. Kirk B. Burkhart, Nick Burton, Shuo Luo, Bob Horvitz.

728A. Y39G10AR.7 is a putative MPK-1 Erk target during excretory duct cell fate specification. Preston Chin, Phil Cheng, Christian Rocheleau.

729B. An RNAi screen for maternal factors influencing endoderm specification. Hailey H. Choi, Morris F. Maduro.

730C. Characterization of a BMP negative regulator in the extracellular matrix. Y. J. Ang, King-Lau Chow.

731A. The role of the claudin-like gene nsy-4 in C. elegans sensory ray development. King L. Chow, Kei C. Fan.

732B. Transcriptional Regulation of the Hox gene lin-39 by LIN-31, a Winged-Helix Transcription Factor Involved in C. elegans Cell Fate Specification. A. Dewey, F. Meza Gutierrez, C. Morris-Singer, L. Miller.

733C. Elucidating the role of nmy-2 in seam cell division patterns. Siyu S. Ding, Peter J. Appleford, Alison Woollard.

734A. Imaging developmental landscape of C. elegans embryos. Zhuo Du, Anthony Santella, Fei He, Michael Tiongson, Zhirong Bao.

735B. The let-7 microRNA is dispensable for early vulva cell fate specification, but is required for later stages of vulva development. Matyas Ecsedi, Helge Grosshans.

736C. Suppressors of pos-1 identify a novel function for GLP-1 and new players, gld-3, cyclin E and spos-1, involved in endoderm specification. Ahmed Elewa, Masaki Shirayama, Sandra Vergara, Takao Ishidate, Craig Mello.

737A. Defining genetic pathways of disease through genetic suppression screening in C. elegans. Amy Fabritius, Andy Golden.

738B. Asymmetric regulation of the human VAX ortholog homeobox gene ceh-5 during early neurogenesis in Caenorhabditis elegans. Umesh Gangishetti, Lois Tang, Johan Henriksson, Thomas R. Burglin.

739C. Investigating the role of SEM-4/SALL in development of the postembryonic mesoderm. Vikas Ghai, Chenxi Tsian, Jun Liu.

740A. Defining the role of the Caenorhabditis elegans homeobox protein, PAL-1, in the development of the stem-like seam cells. Sophie P. R. Gilbert, Charles Brabin, Peter J. Appleford, Alison Woollard.

741B. When two become one: Sperm-egg fusion during C. elegans fertilization. Boaz Gildor, Meital Oren, Benjamin Podbilewicz.

742C. The Mediator subunit CDK-8 is a dual negative/positive regulator of EGFR-Ras-MAPK signaling. Jennifer M. Grants, Lisa TL Ying, Stefan Taubert.

743A. Genetic analysis of vulval development in C. briggsae. Bhagwati P. Gupta, Devika Sharanya, Bavithra Thillainathan, Cambree J. Fillis, Kelly A. Ward, Edward M. Zitnik, Molly E. Gallagher, Helen M. Chamberlin.

744B. A role for UNC-55 in AS motor neuron subtype specification. Michael Hart, Oliver Hobert.

745C. Identification of hcf-1 as a dsh-2 suppressor. Kyla Hingwing, Tammy Wong, Jack Chen, Nancy Hawkins.

746A. HAM-1: An asymmetrically localized transcriptional regulator? Khang Hua, Amy Leung, Maria Wu, Nancy Hawkins.

747B. The small GTPase Ral signals via an Exocyst-GCK-2/MAP4K-p38-MAPKAPK cascade. Rebecca E. W. Kaplan, Channing J. Der, David J. Reiner.

748C. MEX-5 positively regulates mex-3 mRNA at anterior blastomere in early C. elegans embryo. Hiroyuki Konno, Koki Noguchi, Yuji Kohara.

749A. Structure-function of SYS-1/β-catenin, an effector of Wnt-directed asymmetric cell divisions. Koon Yee Lam, Michael Molumby, Jennifer Hutchinson, Lori Adams, Bryan Phillips.

750B. Towards sequencing key cells of the developing Caenorhabditis elegans vulva. James Lee, Pei Shih, Paul Sternberg.

751C. UNC-40 positively modulates BMP signaling independent of netrin signaling. Chenxi Tian, Herong Shi, Shan Xiong, Fenghua Fu, Wen-Cheng Xiong, Jun Liu.

752A. Regulation of serotonergic neuron patterning in C. elegans by Wnt signaling genes. Curtis M. Loer, Erin Williams.

753B. The role of the C. elegans Jarid1 histone lysine demethylase RBR-2 in vulva cell fate determination. Yvonne C. Lussi, Toshia R. Myers, Anna Elisabetta Salcini.

754C. Animal to Animal Variability During Vulval Cell Fate Specification. Sabrina Maxeiner, Daniel Roiz, Alex Hajnal.

755A. Dynein Heavy Chain-1: a novel negative regulator of LET-23 EGFR induced vulva induction. Jassy Meng, Olga Skorobogata, Christian Rocheleau.

756B. Control of LET-23 localization by PRMT-1 during vulval development. Sabrina Kathrin Merkle, Juan Miguel Escobar-Restrepo, Tobias Schmid, Fabienne Largey, Alex Hajnal.

757C. The role of Wnt and FGF signaling in C. elegans vulval cell lineage polarity. Paul Minor, Paul Sternberg.

758A. Role of the CRL2^LRR-1 ubiquitin ligase in regulating LIN-12/Notch signaling in C. elegans vulva development. Madhumati Mukherjee, Edward T. Kipreos.

759B. Tousled-like Kinase Is Required to Generate a Bilateral Asymmetry in the C. elegans Nervous System. Shunji Nakano, Bob Horvitz, Ikue Mori.

760C. TORC2 Signaling Antagonizes SKN-1 to Induce C. elegans Mesendodermal Embryonic Development. Vanessa Ruf, Christina Holzem, Tobias Peyman, Gerd Walz, T. Keith Blackwell, Elke Neumann-Haefelin.

761A. Identification of mechanisms by which the expression of lim-4 homeodomain gene is regulated to specify the SMB motor neuron fate. Jisoo Park, Jihye Yeon, Kyuhyung Kim.

762B. SOS-1 is required for remodeling epithelial junctions during the G1 excretory pore cell’s transition from epithelial tube to neuroblast. Jean Parry, Meera Sundaram.

763C. Cell Fate Restriction and Reprogramming in C. elegans. Tulsi Patel, Oliver Hobert.

764A. Regulation of Post-embryonic Seam Cell Proliferation and Identity by the Non-Receptor Tyrosine Kinase, FRK-1. Aaron Putzke, Danielle Mila, Katherine Genzink, McLane Watson, Caroline Askonas, Kelsey Moore.

765B. Multiple Aspects of C. elegans Germ Cell Development are Regulated by XND-1. Mainpal Rana, Judith Yanowitz.

766C. Netrin expression in P. pacificus. Brent Wyatt, Kelly Mahoney, David Rudel.

767A. A C. elegans FerT Kinase Regulates Developmental Cell-Cell Fusion to Direct Cell Identity. R. Mako Saito, David Tobin, Sarah Roy.

768B. Differential regulation of HLH-2/E2A stability during gonadogenesis in C. elegans . Maria Sallee, Iva Greenwald.

769C. Quantitative proteome analysis of maternal gene spn-4 mutant in Caenorhabditis elegans. Aimi Tomita, Yukako Toshato, Toshiya Hayano, Masahiro Ito.

770A. Role of sox-2 in postembryonic lineage progression. Berta Vidal Iglesias, Oliver Hobert.

771B. Centrosomal localization of SYS-1/beta-catenin is required for proper expression patterns during asymmetric cell division. Setu M. Vora, Bryan T. Phillips.

772C. ceh-36 regulates cell fate patterning during embryogenesis. Travis Walton, John Murray.

773A. Wnts and VANG-1/Van Gogh control cell fates in the Q lineage. Falina J. Williams, Jerome Teuliere, Gian Garriga.

774B. Glucose 6-phosphate dehydrogenase (G6PD) deficiency impairs early embryogenesis in C. elegans. Hung-Chi Yang, Meng-Hsin Ou, Szecheng J. Lo, Daniel Tsun-Yee Chiu.

775C. Single-blastomere transcriptome profiling after the first embryonic division. Erin Osborne Nishimura, Jay C. Zhang, Adam Werts, Bob Goldstein, Jason D. Lieb.

776A. Genome-wide landscape of hybrid incompatibility (HI) between Caenorhabditis briggsae and C. sp.9 . Zhongying Zhao, Cheung Yan, Yu Bi, Xiaoliang Ren, Dongying Xie.

Development and Evolution: Cell Death and Neurodegeneration

777B. Perturbation of NAD+ salvage biosynthesis causes a distinct death program in a neuroendocrine cell. Awani Awani, Matt Crook, Wendy Hanna-Rose.

778C. A C. elegans model for TDP-43-induced motor neuron pathology. J. C. Chaplin, M. Mangelsdorf, R. Narayanan, R. Wallace, M. A. Hilliard.

779A. Elucidating the mechanism by which C.elegans KRI-1 regulates damaged-induced germline apoptosis. Eric M. Chapman, W. Brent Derry.

780B. Using Caenorhabditis elegans to Fight Human Neurodegenerative Diseases. Xi Chen, Brian C. Kraemer, Jeff Barclay, Robert D. Burgoyne, Alan Morgan.

781C. C. elegans peroxidasin, pxn-1 is essential for epidermal attachment of muscles and neurons. Jeong H. Cho, Juyeon Lee.

782A. Analysis of the Function and Dysfunction of the Human Amyotrophic Lateral Sclerosis Gene C9ORF72 Using C. elegans. Anna Corrionero, Bob Horvitz.

783B. Blocking NAD+ salvage biosynthesis sensitizes specific mechanosensory neurons to nutritional conditions and predisposes them to death. Matt Crook, Wendy Hanna-Rose.

784C. EGF and phosphocholine; a novel mechanism to prevent necrosis. Matt Crook, Wendy Hanna-Rose.

785A. BRAP-2 is necessary for the regulation of DNA damage induced germ line apoptosis in C. elegans. Dayana R. D'Amora, Terrance J. Kubiseski.

786B. The Possible Role of Autophagic Cell Death in the Regulation of Excitotoxicity in C. elegans. John S. Del Rosario, Towfiq Ahmed, JunHyung An, Tauhid Mahmud, Itzhak Mano.

787C. Investigation of SMN1 structure-function relationship in neuronal degeneration. A. Donato, I. Gallotta, G. Battaglia, M. A. Hilliard, P. Bazzicalupo, E. Di Schiavi.

788A. ced-11 is Required for the Morphological Appearance of Apoptotic-Cell Corpses. Kaitlin B. Driscoll, Gillian Stanfield, Bob Horvitz.

789B. Diapause protects neurons from degeneration and promotes axonal regrowth. Andres Fuentes, Andrea Calixto.

790C. UNC-105 activation causes mitochondrial dysfunction and CED-4 dependent caspase-mediated protein degradation in terminally differentiated C. elegans muscle. C. J. Gaffney, F. Shephard, J. Chu, D. L. Baillie, A. Rose, D. Constantin-Teodosiu, P. L. Greenhaff, N. J. Szewczyk.

791A. Neurodegeneration and death induced by neuron-specific knock-down of smn-1, the homolog of the gene responsible for Spinal Muscular Atrophy. I. Gallotta, A. Donato, N. Mazzarella, P. Bazzicalupo, M. Hilliard, E. Di Schiavi.

792B. Chronic alcohol exposure induces toxicity and neurodegeneration in C. elegans. Lina Gomez, Sangeetha Iyer, Ashley Crisp, Jesse Cohn, Jon Pierce-Shimomura.

793C. Functional analysis of VPS41-mediated protection from β-Amyloid cytotoxicity. Edward F. Griffin, Christopher Gilmartin, Kim A. Caldwell, Guy A. Caldwell.

794A. SGK-1 promotes germline apoptosis by a cell non-autonomous mechanism. Madhavi Gunda, W.Brent Derry.

795B. The Sodium-Potassium ATPase alpha subunit EAT-6 promotes programmed cell death. Tsung-Yuan Hsu, Meng- I. Lee, Yi-Chun Wu.

796C. Innate immune signaling protects against patterned neurodegeneration in Alzheimer’s disease. Sangeetha V. Iyer, Ashley Crisp, Anushri Kushwaha, Jon Pierce-Shimomura.

797A. Sirtuin Mediated Neuroprotection and its Association with Autophagy and Apoptosis: Studies Employing Transgenic C. elegans Model. Pooja Jadiya, Aamir Nazir.

798B. LIN-3/EGF promotes programmed cell death by transcriptional activation of the pro-apoptotic gene egl-1. Hang-Shiang Jiang, Yi-Chun Wu.

799C. Assisted Suicide: a Caspase- and Engulfment-Dependent Cell Death. Holly Johnsen, Bob Horvitz.

800A. Modulation of mec-10(d)-induced necrosis by ER chaperone NRA-2. Shaunak Kamat, Shrutika Yeola, Monica Driscoll, Laura Bianchi.

801B. Mutations in progranulin and cell death genes confer organismal stress resistance. M. Judy, A. Nakamura, H. McCurdy, A. Huang, H. Grant, C. Kenyon, A. Kao.

802C. A C. elegans model of Adult-onset Neuronal Ceroid Lipofuscinosis reveals a sir-2.1 independent protective effect of resveratrol. Sudhanva Kashyap, James Johnson, Mimi Ayala, Jeff Barclay, Bob Burgoyne, Alan Morgan.

803A. Post-transcriptional control of C. elegans germ cell apoptosis by RNA-binding proteins. Martin Keller, Michael O. Hengartner.

804B. Investigating neuroprotecive genes on S. venezuelae toxicity in C. elegans. H. Kim, G. A. Caldwell, K. A. Caldwell.

805C. Using artificial insemination to identify genes involved in linker cell death and corpse removal. Lena M. Kutscher, Nima Tishbi, Shai Shaham.

806A. Identification of interacting partners of a poly-glutamine protein involved in non-apoptotic cell death. Lena M. Kutscher, Shai Shaham.

807B. Necrotic Cells Share a Similar Mechanism with Apoptotic Cells in being Recognized by Engulfing Cells in C. elegans. Zao Li, Victor Venegas, Prashant Raghavan, Yoshinobu Nakanishi, Zheng Zhou.

808C. A small metabolite isolated from Streptomyces venezuelae enhances age-dependent proteotoxic stress in C. elegans models of neurodegenerative diseases. B. A. Martinez, A. Ray, G. A. Caldwell, K. A. Caldwell.

809A. Unraveling the role of MOAG-4 in protein aggregation. A. T. van der Goot, A. Mata-Cabana, E. Stroo, E. A. Nollen.

810B. Neuronal expression of wild-type and A152T mutant tau cause distinct patterns of toxicity in C. elegans. Helen L. McCurdy, D. Cox, B. Bliska, Aimee W. Kao.

811C. Neuronal Exophers: a Novel Mechanism for Removal of Neurotoxic Cytoplasm Components. Ilija Melentijevic, Marton Toth, Christian Neri, Monica Driscoll.

812A. Progressive degeneration of dopaminergic neurons through TRP channel-induced necrosis. Archana Nagarajan, Ye Ning, Oliver Hobert, Maria Doitsidou.

813B. MEC-17 protects from axonal degeneration, maintaining mitochondrial organization and axonal transport. Brent Neumann, Massimo Hilliard.

814C. Axonal degeneration in C. elegans proceeds independently from the WldS pathway. Annika L. A. Nichols, Brent Neumann, Ellen Meelkop, Massimo A. Hilliard.

815A. Cell-Nonautonomous Inhibition of Radiation-Induced Apoptosis by Dynein Light Chain 1 in Caenorhabditis elegans. Tine H. Møller, Anna Dippel Lande, Anders Olsen.

816B. TPPP/p25α causes degeneration of dopaminergic neurons in C.elegans. Katrine Christensen, Lotte Vestergaard, Rikke Kofoed, Anders Olsen.

817C. Bacterial metabolite causes mitochondrial dysfunction and oxidative stress in a C. elegans Parkinson’s disease model. A. Ray, B. A. Martinez, G. A. Caldwell, K. A. Caldwell.

818A. A Small-Molecule Screen for Linker Cell Death Inhibitors. Andrew Schwendeman, Shai Shaham.

819B. C. elegans clathrin and its adaptor epsin promote apoptotic-cell engulfment through regulating cytoskeleton remodeling. Qian Shen, Bin He, Nan Lu, Barbara Conradt, Barth D. Grant, Zheng Zhou.

820C. Glucose influences aging, proteotoxicity and stress response in C. elegans. Arnaud Tauffenberger, Alexandra Vaccaro, J. Alex Parker.

821A. Cortical HAM-1 positions the cleavage furrow in myosin-dependent asymmetric neuroblast divisions that generates apoptotic cells. Jerome Teuliere, Nancy Hawkins, Gian Garriga.

822B. The DNA binding protein dpff-1 is required to trigger starvation-induced germ cell apoptosis. Angel E. Villanueva Chimal, Rosa E. Navarro.

823C. Characterization of a Chloride-Mediated Cell Death Pathway in C.elegans PLM Neurons. Claudia M. Wever, Aamna Kaul, Miles Byworth, Joseph A. Dent.

824A. Genetic modifiers of amyloid-beta toxicity in C. elegans Alzheimer’s disease models. Xiaohui Yan, Adam L. Knight, Kim A. Caldwell, Guy A. Caldwell.

825B. Comparisons of three C. elegans DNase II activities in vitro and in vivo. Hsiang Yu, Szecheng J. Lo.

Development and Evolution: Development Timing

826C. Functional characterization of lin-41 and its targets. Hrishikesh Bartake.

827A. Activity and functional interactions of the leucine-rich protein PAN-1 during larval development. Derrick L. Cardin, Chris R. Gissendanner.

828B. Roles of C. elegans LIN-28 in hermaphrodite fertility and embryonic viability. Sungwook Choi, Anna Zinovyeva, Victor Ambros.

829C. Significant Transcription in Zygote Pronuclei and 1-4 Cell Embryos Drives Early Development in the Nematode, Ascaris suum. Richard E. Davis, Julianne Roy, Jianbin Wang.

830A. Regulation of Developmental Timing and Cell-Fate Determination by MAB-10 and LIN-29. Akiko Doi, Bob Horvitz.

831B. A lin-42 null allele: highly penetrant defects in developmental timing and molting. Theresa L. B. Edelman, Katherine A. McCulloch, Angela Barr, Christian Frøkjaer-Jensen, Erik M. Jorgensen, Ann E. Rougvie.

832C. Hypodermis integrates nutrient signaling to regulate blast cell quiescence. M. Fukuyama, K. Kontani, A. Rougvie, T. Katada.

833A. Dynamically-expressed prion-like proteins form a cuticle in the pharynx of Caenorhabditis elegans. J. B. George-Raizen, K. R. Shockley, A. L. Lamb, D. M. Raizen.

834B. LEP-2/Makorin represses LIN-28 to keep nematode tail tip differentiation on schedule. R. Antonio Herrera, Karin Kiontke, David Fitch.

835C. The C. elegans plasminogen/HGF-like protein SVH-1 is required for larval developmental growth. Naoki Hisamoto, Motoki Yoshida, Chun Li, Kunihiro Matsumoto.

836A. BLMP-1/BLIMP1 - a novel substrate of the DRE-1/FBXO11 SCF complex that regulates C. elegans developmental timing. Moritz Horn, Christoph Geisen, Adam Antebi.

837B. Ascaroside signals suppress heterochronic phenotypes of the daf-12(rh61) mutant. Orkan Ilbay, Zhiji Ren, Jagan Srinivasan, Frank C. Schroeder, Victor Ambros.

838C. Post-dauer regulation of developmental timing. Stephen Domingue, Benjamin Prout, Xantha Karp.

839A. Heterochronic gene lin-46: protein expression and interaction with HBL-1. Kevin Kemper, Bhaskar Vadla, Eric G. Moss.

840B. A comparative analysis of the genetic basis of molting in the necromenic nematode Pristionchus pacificus. Victor Lewis, Maryn Cook, Justin Alonso, Ray Hong.

841C. Low population density increases lifespan and delays egg laying of C. elegans hermaphrodites. Andreas H. Ludewig, Frank C. Schroeder, Frank Doering.

842A. The C. elegans period homolog lin-42 regulates the timing of heterochronic miRNA expression. K. A. McCulloch, A. E. Rougvie.

843B. Insulin-regulated nutritional checkpoints in post-dauer C. elegans larval development. Adam J. Schindler, L. Ryan Baugh, David R. Sherwood.

844C. Transcription factors involved in dauer recovery. Pei-Yin Shih, Paul W. Sternberg.

845A. What is lin-28’s let-7 independent mechanism? Jennifer Tsialikas, Bhaskar Vadla, Kevin Kemper, Eric Moss.

846B. A Quantitative Approach Reveals the Conditional Role of elt-7 in the C. elegans Intestinal Specification Network. Allison Wu, Scott Rifkin.

847C. A high-throughput genetic screen for lethargus mutants. C. Yu, M. Churgin, D. Raizen, C. Fang-Yen.

Development and Evolution: Germline Development, Meiosis and Sex Determination

848A. CYP35A3-GFP induction and reproductive toxicity of environmental samples in C.elegans. A. Abbas, L. Valek, J. Oehlmann, M. Wagner.

849B. GLD-1 Expression During Germline Development. Jennifer R. Aleman, Sudhir B. Nayak.

850C. Role of autophagy genes in C.elegans germline proliferation. K. Ames, A. Meléndez.

851A. Anillin promotes syncytial organization and maintenance of the C. elegans germline. Rana Amini, Sara Labella, Monique Zetka, Amy S. Maddox, Nicolas T. Chartier, Jean-Claude Labbé.

852B. Structural characterization of the P-granule protein scaffold. Scott Takeo Aoki, Judith Kimble.

853C. FOG-1 and FOG-3, their mRNA targets and the sperm/oocyte fate decision. Daniel Noble, Marco Ortiz, Scott Aoki, Kyung Won Kim, Judith Kimble.

854A. Homeodomain interacting protein kinase (HPK-1) is required in the soma for robust germline proliferation in C. elegans. S. Berber, E. Llamosas, P. Boag, M. Crossley, H. Nicholas.

855B. Identification of direct targets of the Caenorhabditis elegans global sexual regulator TRA-1 by ChIP-seq. Matt Berkseth, Kohta Ikegami, Jason Lieb, David Zarkower.

856C. The Role of Sperm Specific PP1 Phosphatase GSP-3/4 in Kinetochore Localization and Function During Spermatogenesis. Joseph Beyene, Diana Chu, PhD.

857A. Exploring miRNA function in the proliferation versus meiosis decision in the C. elegans germline. John L. Brenner, Gavriel Y. Matt, Tim Schedl.

858B. Distal tip cell processes provide extensive contact between the germline stem cell pool and its cellular niche. Dana T. Byrd, Karla Knobel, Katharyn Schmitt, Sarah L. Crittenden, Judith Kimble.

859C. PUF-8 controls mitochondrial biogenesis and apoptosis in the germline. A. Chaturbedi, G. Anil Kumar, M. Ariz, K. Subramaniam.

860A. Timing is everything: dissecting the male sperm activation pathway. Daniela Chavez, Joseph Smith, Angela Snow, Gillian Stanfield.

861B. The Nucleosome Remodeling Factor complex controls germ cell fates in C. briggsae. Xiangmei Chen, Ronald E. Ellis.

862C. An importin β controls the sperm/oocyte decision in C. briggsae. Xiangmei Chen, Greg Minevich, Yongquan Shen, Alexander Boyanov, Oliver Hobert, Ronald E. Ellis.

863A. Control of cell cycling speed to minimize mutation accumulation. Michael Chiang, Amanda Cinquin, Olivier Cinquin.

864B. Progress on developing the Q system to study GSCs and their control. Sarah L. Crittenden, Ipsita Mohanty, Judith Kimble.

865C. Giving Light to Sperm-Specific Phosphatases. Tyler S. Curran, Leslie Mateo, Diana Chu.

866A. Signaling pathways that mediate the deleterious effects of dietary fatty acids in the germ line. Marshall Deline, Jennifer L. Watts.

867B. A Quality Control Mechanism Coordinates Meiotic Prophase Events. Alison J. Deshong, Alice L. Ye, Piero Lamelza, Needhi Bhalla.

868C. GLD-4, a cytoplasmic poly(A) polymerase, is part of a translational feedback loop regulating stem cell pool size and meiotic entry in the adult C. elegans germ line. Sophia Millonigg, Ryuji Minasaki, Marco Nousch, Christian R. Eckmann.

869A. Gamma Secretase Function During Germline Development. Cassandra Farnow, Ipsita Agarwal, Caitlin Greskovich, Caroline Goutte.

870B. Nuclear Envelope Components and Dynein act Coordinately with MEL-28 to Promote Post-Embryonic Development. Anita G. Fernandez, Allison Lai, Carly Bock, Angela Quental, Mike Mauro, Emily Mis, Fabio Piano.

871C. SPCH-1/2/3 localize to mature sperm chromatin and may play a role in fertility and genome stability. Jennifer Gilbert, Dana Byrd, Jordan Berry, Diana Chu.

872A. Differential expression of germline genes in the presence/absence of H3K9me2. Yiqing Guo, Eleanor Maine.

873B. MRG-1 and RFP-1 regulate proliferation in the germline. Pratyush Gupta, Lindsay Leahul, Katie Jasper, David Hansen.

874C. The RNA binding protein TIAR-1 is essential for C. elegans fertility. Gabriela Huelgas Morales, Carlos G. Silva García, Rosa E. Navarro.

875A. Exploring the contribution of chromosomal context in shaping the C. elegans high-resolution recombination rate landscape. Taniya Kaur, Matthew Rockman.

876B. RNA recognition by OMA-1, a C. elegans oocyte maturation determinant. Ebru Kaymak, Sean P. Ryder.

877C. Characterization of non-SMC elements of the SMC-5/6 complex in C. elegans. Jayshree Khanikar, Jaclyn Fingerhut, Jeremy Bickel, Raymond Chan.

878A. Novel spermatogenesis-defective gene candidates. Takashi Koyama, Megumi Endo, Yusuke Hokii, Chisato Ushida.

879B. Identifying regulators of sex-specific gonadal development in C. elegans by cell-specific RNA-seq. Mary B. Kroetz, David Zarkower.

880C. Y23H5A.4 is a sperm gene that encodes a mitochondrially-associated protein involved in spermatid activation. Craig W. LaMunyon, Ubaydah Nasri, Nicholas Sullivan, Jessica Clark.

881A. DNA damage response and spindle assembly checkpoint collaborate to elicit cell cycle arrest in response to replication defects in the C. elegans male germ line. Kate Lawrence, JoAnne Engebrecht.

882B. Elucidating how TRA-1 promotes spermatogenesis in C. briggsae. Shin-Yi Lin, Yiqing Guo, Ronald E. Ellis.

883C. Molecular analysis of ego-3, an enhancer of glp-1. Jim Lissemore, Elyse Connors, Ying Liu, Eleanor Maine.

884A. DAF-2 and ERK regulate C. elegans oogenesis as a physiological adaptive response to nutrient availability. Andrew Lubin Lopez, Jessica Chen, Hyoe-Jin Joo, Melanie Drake, Miri Shidate, Cedric Kseib, Swathi Arur.

885B. C. elegans p53/p63 protein CEP-1 promotes meiotic recombinational repair. Abigail Rachele Mateo, Kristine Jolliffe, Alissa Nicolucci, Bin Yu, Olivia McGovern, Zebulin Kessler, Judith Yanowitz, W. Brent Derry.

886C. Acetylation of H2AK5 and genome instability in xnd-1 mutants. Brooke McClendon, Judith Yanowitz.

887A. Mechanism of Germ Cell Loss by Ionizing Radiation in a C. elegans Tumor Model. David Michaelson, Xinzhu Deng, Diana Rothenstein, Regina Feldman, Simon Powell, Zvi Fuks, E. Jane Albert Hubbard, Richard Kolesnick.

888B. Temperature Sensitive Fertility of lin-35 Mutants. Brian P. Mikeworth, Lisa N. Petrella.

889C. Spermiogenesis regulation involves multiple sperm cell compartments as revealed through a suppressor screen of spe-27. Ubaydah Nasri, Misa Austin, Nicholas Sullivan, Craig LaMunyon.

890A. Deletion of ccm-3 in C. elegans promotes increased accumulation of reactive oxygen species resulting in apoptosis of germline cells. Swati Pal, Bin Yu, W. Brent Derry.

891B. Selective elimination of male-producing sperm by apoptosis in a nematode. Manish Parihar, Sarah Smith, Andre Pires da Silva.

892C. Visualizing dynamics of meiotic prophase chromosome structures. Divya Pattabiraman, Baptiste Roelens, Marc Presler, Grace Chen, Anne Villeneuve.

893A. Live imaging reveals active infiltration of mitotic zone by its stem cell niche. Adrian Paz, Brandon Wong, Amanda Cinquin, Elliot Hui, Olivier Cinquin.

894B. Regulation of TGFβ signaling in germline stem cell development in C. elegans. O. Pekar, E. J. A. Hubbard.

895C. Localization dynamics of SPE-6, a sperm-specific CK1 in C. elegans. Jackson Peterson, Brianna Waller, Diane Shakes.

896A. Ascaroside-mediated sex determination in a nematode with three genders. Vikas Kache, Stephan H. von Reuss, Joshua Yim, Jyotiska Chaudhuri, Christine Bateson, Frank Schroeder, Andre Pires da Silva.

897B. Effect of Synapsis Challenges on Meiotic Progression. Baptiste Roelens, Susanna Mlynarczyk-Evans, Anne Villeneuve.

898C. Elucidating the role of S6K-Notch interactions in cell fate specification in the C. elegans germ line. Debasmita Roy, E. Jane Albert Hubbard.

899A. Assembly of RNP granules in C. elegans oocytes promotes oocyte quality and is regulated by the cytoskeleton. Megan Wood, Angela Hollis, Kevin Gorman, Joseph Patterson, Ashley Severance, Gregory Davis, Peter Boag, Jennifer Schisa.

900B. Nutritional Control of Germline Stem Cells in Caenorhabditis elegans. Hannah S. Seidel, Judith Kimble.

901C. IFET-1 an eIF4E-binding protein is required for normal P-granules formation and translational regulation of mRNAs. Madhu S. Sengupta, Peter R. Boag.

902A. PQN-94 regulates hermaphrodite development by interacting with SHE-1. Yongquan Shen, Ronald E. Ellis.

903B. Characterization of SYGL-1, a novel regulator of germline stem cells. Heaji J. Shin, Kimberly Haupt, Aaron M. Kershner, Judith Kimble.

904C. The Role of Condensin I during Meiosis. M. Sifuentes, K. Colette, G. Csankovszki.

905A. UBC-25 promotes Ras/MAPK signaling to regulate oocyte growth and embryonic morphogenesis in C. elegans. Mideum Song, Kevin Cullison, Phil Cheng, Meera Sundaram, Christian Rocheleau.

906B. GLP-1/Notch signaling in germline stem cell maintenance. Erika B. Sorensen, Amy C. Groth, Judith Kimble.

907C. Loss of UNC-84 in the C. elegans germ line activates the recombination and synapsis checkpoints. Erin Tapley, Kate Lawrence, K. C. Hart, JoAnne Engebrecht, Daniel Starr.

908A. The SACY-1 DEAD-box RNA helicase genetically interacts with components of the spliceosome. Seongseop Kim, Tatsuya Tsukamoto, David Greenstein.

909B. The Torsin Homolog OOC-5 is Required for Normal Nucleoporin Localization. Michael J. W. VanGompel, Sumati Hasani, Lesilee S. Rose.

910C. Cellular machinery promoting FBF-2 regulatory activity. Xiaobo Wang, Dominique Rasoloson, Elle Johnson, Ekaterina Voronina.

911A. Asymmetric segregation of P granules requires granule remodeling by two novel serine-rich proteins. Jennifer T. Wang, Geraldine Seydoux.

912B. Investigating the cellular mechanisms of skewed sex ratios in non-C. elegans nematodes. Ethan S. Winter, Diane C. Shakes.

913C. Regulation of Apoptosis by Meiotic Checkpoint Proteins: New Roles for egl-1 and ced-13. Alice L. Ye, Matt Ragle, Barbara Conradt, Needhi Bhalla.

914A. MRX/N Commits Homologous Recombination of Meiotic Double-Strand-Breaks by Promoting Resection, Antagonizing Non-Homologous End Joining, and Stimulating EXO-1 in Caenorhabditis elegans. Yizhi Yin, Sarit Smolikove.

Development and Evolution: Evolution

915B. If we have children together, will they be less fit? Hybrid incompatibilities in Caenorhabditis species. Piero Lamelza, Jerome Cattin, Vanessa Wilson, Irini Topalidou, Michael Ailion.

916C. Gene movement between X and autosomes and its effect on transcription. Sarah E. Albritton, Anna-Lena Kranz, Sevinc Ercan.

917A. Revisiting the effects of spontaneous mutations on the (micro)environmental variance in Caenorhabditis. Charles F. Baer, Erik C. Andersen, Reza Farhadifar, Daniel Needleman.

918B. Evolution of a Higher Intracellular Oxidizing Environment in Caenorhabditis elegans Under Relaxed Selection. Joanna Joyner-Matos, Kiley A. Hicks, Dustin Cousins, Michelle Keller, Dee R. Denver, Charles F. Baer, Suzanne Estes.

919C. Natural variation and sensory biology of C. elegans hermaphrodite control of mating. Adam K. Bahrami, Yun Zhang.

920A. The hunt for quantitative trait nucleotides: a near-isogenic line based approach in C. elegans. Max Bernstein, Matthew Rockman.

921B. Evolution and plasticity of embryo retention in Caenorhabditis nematodes. Paul Vigne, Christian Braendle.

922C. Evolution of ZIM proteins in Caenorhabditis. Victoria Cattani, Matthew Rockman.

923A. Population genomic variation in the outcrossing species Caenorhabditis remanei. Cristel G. Thomas, Janna L. Fierst, John H. Willis, Wei Wang, Richard Jovelin, Patrick C. Phillips, Asher D. Cutter.

924B. RhabditinaDB: online database for wild worms. D. Fitch, K. Kiontke.

925C. Microevolution and coexistence of Santeuil and Le Blanc viruses in Caenorhabditis briggsae. . Lise Frézal, Marie-Anne Félix.

926A. Evolution of avermectin resistance in C. briggsae. Rajarshi Ghosh, Cristel Thomas, Wei Wang, Richard Jovelin, Asher Cutter, Leonid Kruglyak.

927B. Strong outbreeding depression and low genetic diversity in the selfing Caenorhabditis sp. 11. Clotilde Gimond, Richard Jovelin, Shery Han, Celine Ferrari, Asher D. Cutter, Christian Braendle.

928C. Fainting towards Necromeny: Anesthesia caused by a Beetle Pheromone is Mediated by a Lipid-Binding Protein in Pristionchus pacificus. James L. Go, Jessica K. Cinkornpumin, Margarita Valenzuela, Roonalika D. Wisidagama, Ray L. Hong.

929A. Cross Species NILs - A Resource for Speciation, Evolution and Development. Jeremy C. Gray, Joanna Bundus, Asher D. Cutter.

930B. Widespread pleiotropic Bateson-Dobzhansky-Muller incompatibilities between C. elegans isolates. Helen E. Orbidans, L. Basten Snoek, Jana Stastna, Jan E. Kammenga, Simon C. Harvey.

931C. Comparative mapping of dauer larvae development in growing populations of C. elegans and C. briggsae. James W. M. Green, Simon C. Harvey.

932A. Co-evolution of Mitochondrial and Nuclear Genomes in Caenorhabditis. Emily E. King, Scott E. Baird.

933B. The latest update on Caenorhabditis species, their ecology, phylogeny, and morphology. Karin C. Kiontke, Marie-Anne Félix, David H. A. Fitch.

934C. Evidence for at least two ancient duplications of presenilin genes in the nematode phylum. Bernard Lakowski.

935A. The Role of Pharyngeal Glands in Nematode Feeding and Diet. James W. Lightfoot, Ralf J. Sommer.

936B. Genomic Analysis of Hox Genes in Five Steinernema Genomes. Marissa Macchietto, Adler Dillman, Ali Mortazavi, Paul Sternberg.

937C. Interactions of C. elegans with its gut microbiota: from sampling in the wild to molecular genetic studies. Sarah E. Marsh, Marie-Anne Félix.

938A. From locus to nucleotide to phenotype: mapping the genetic architecture of quantitative traits. Luke M. Noble, Matthew V. Rockman.

939B. C. elegans harbors pervasive cryptic genetic variation for embryogenesis. Annalise B. Paaby, Amelia White, Kris Gunsalus, Fabio Piano, Matt Rockman.

940C. Natural Variants of C. elegans demonstrate defects in both sperm function and oogenesis at elevated temperatures. Lisa N. Petrella, Thomas Buskuskie, Susan Strome.

941A. The evolution of nematode operons. Jonathan Pettitt, Henrike Goth, Debjani Sarkar, Lucas Phillippe, Bernadette Connolly, Berndt Muller.

942B. Elucidating the cellular and genetic basis of hybrid dysfunction between wild isolates of Caenorhabditis briggsae. Kevin Pham, Joseph Ross.

943C. Environmental sensitivity and evolution of Caenorhabditis germline proliferation and differentiation. Nausicaa Poullet, Anne Vielle, Christian Braendle.

944A. Survey of C. elegans local polymorphism in an apple orchard by RAD-sequencing. Aurélien Richaud, Marine Stefanutti, Marie-Anne Félix.

945B. The rate and spectrum of spontaneous mutations in experimental populations of the nematode Caenorhabditis remanei. Matthew P. Salomon, Chikako Matsuba, Dejerianne G. Ostrow, Charles F. Baer.

946C. Evolution of Nematode Spliced Leader trans-splicing. Debjani Sarkar, Berndt Müller, Bernadette Connolly, Jonathan Pettitt.

947A. Embryogenesis of nematodes: traveling through transcriptomes. Christopher Kraus, Einhard Schierenberg.

948B. Major changes in the core developmental pathways of nematodes: Romanomermis culicivorax reveals the derived status of the Caenorhabditis elegans model. Philipp Schiffer, Michael Kroiher, Christopher Kraus, Georgios Koutsovoulos, Sujai Kumar, Julia Camps, Ndifon Nsah, Dominik Stappert, Krystalynne Morris, Peter Heger, Janine Altmüller, Peter Frommolt, Peter Nürnberg, Kelley Thomas, Mark Blaxter, Einhard Schierenberg.

949C. Assortative Fertilization in the Elegans-Group of Caenorhabditis. Sara R. Seibert, Blaine E. Bittorf, Scott E. Baird.

950A. Complex regulation of C. briggsae tra-1. Yongquan Shen, Yiqing Guo, Ronald E. Ellis.

951B. Inferring the order of mutational changes responsible for mechanistic divergence of a functionally constrained promoter. Mohammad Siddiq, Antoine Barriere, Ilya Ruvinsky.

952C. Gene-environment interactions drive genomic and transcriptomic diversity in wild Caenorhabditis elegans populations. R. J. M. Volkers, L. B. Snoek, C. J. van Hellenberg hubar, R. Coopman, W. Chen, M. G. Sterken, H. Schulenburg, B. P. Braekman, J. E. Kammenga.

953A. From C. elegans to parasitic nematodes: Strongyloides spp. and Onchocerca spp. Adrian Streit.

954B. Genetic and developmental mechanisms underlying sperm size variation in Caenorhabditis nematodes. Anne Vielle, Nuno Soares, Nicolas Callemeyn-Torre, Nausicaa Poullet, Christian Braendle.

955C. Testing for non-Mendelian assortment of chromosomes in Caenorhabditis. Son Tho Le, Chia-Yi Kao, John Wang.

956A. Using TALENs to create new genetic model systems. Qing Wei, Yongquan Shen, Xiangmei Chen, Yelena Shifman, Ronald E. Ellis.

Gene Regulation and Genomics: Gene Expression

957B. BAR-1/beta-catenin regulates expression of a subset of collagen genes that are necessary for normal adult cuticle integrity. B. Jackson, P. Abete Luzi, D. Eisenmann.

958C. Long non-coding RNAs have conserved developmental gene expression patterns. Gal Avital, Michal Levin, Itai Yanai.

959A. Pervasive cis-regulatory divergence despite functional conservation in Caenorhabditis nematodes. Antoine Barriere, Ilya Ruvinsky.

960B. Multiple HRG-1 paralogs regulate heme homeostasis in C. elegans. Haifa B. Bensaidan, Iqbal Hamza.

961C. Antibiotics can modulate the immune system to enhance survival of Caenorhabditis elegans during Yersinia pestis infection. Yun Cai, Alejandro Aballay.

962A. An RNA-Seq based, longitudinal study of root-knot nematode parasitism. Soyeon Cha, Peter DiGennaro, Dahlia Nielsen, David Mck. Bird.

963B. Function of APL-1, a protein related to human APP, which has been implicated in Alzheimer’s Disease. Shah Nawaz Chaudhary, Adanna Alexander, Christine Li.

964C. Reverse genetics and functional analysis of an uncharacterized cysteine rich gene family in Caenorhabditis elegans. Poulami Chaudhuri, Dr Stephen Sturzenbaum.

965A. Deciphering a genetic regulatory network of the ALA neuron. Elly S. Chow, Erich M. Schwarz, Cheryl Van Buskirk, Paul W. Sternberg.

966B. Systematic analysis of cis-acting elements of a key transcription factor regulating C. elegans ray assembly -tbx-2. Kelvin K. K. Ip, King-Lau Chow.

967C. Identification of essential genes that alter L1-diapause recovery. Shu Yi Chua, Jeffrey S. C. Chu, Robert Johnsen, Ann M. Rose, David L. Baillie.

968A. A prime and boost mechanism drives left/right asymmetric expression of the miRNA lsy-6 resulting in neuronal functional asymmetry. Luisa Cochella.

969B. Structural and functional analysis of a daf-16 homolog in the parasitic nematode Brugia malayi. Kirsten Crossgrove, Katherine Stanford, Alexius Folk, Chris Veldkamp.

970C. Identification of Phorbol Ester Responsive Genes in C. elegans Using Genome-wide Expression Analysis. Ana DePina, Xiugong Gao, Piper Hunt, Nicholas Olejnik, Andriy Tkachenko, Renate Reimschuessel, Jeffrey Yourick, Robert Sprando.

971A. Transcription of the cadmium-responsive genes numr-1 and numr-2 is neuronally regulated. Queying Ding, Jonathan H. Freedman.

972B. Functional interplay of two SWI/SNF chromatin-remodeling subunits during C. elegans development. Iris Ertl, Montserrat Porta-de-la-Riva, David Aristizabal-Corrales, Eva Gomez-Orte, Laura Fontrodona, Eric Cornes, Simo Schwartz, Juan Cabello, Julian Ceron.

973C. The C. elegans ATPase inhibitors MAI-1 and MAI-2 are localized in different cellular compartments. Laura P. Fernández-Cárdenas, L. S. Salinas-Velázquez, L. T. Agredano-Moreno, L. F. Jiménez-García, M. Tuena de Gómez Puyou, R. E. Navarro.

974A. Actively Transcribed Reverse Transcriptases are Correlated with Hookworm Larval Development. Xin Gao, Sahar Abubucker, John Hawdon, Makedonka Mitreva.

975B. The role of non-coding RNAs in gene regulation. Kah Yee Goh, Takao Inoue.

976C. Characterization of the Caenorhabditis elegans REF-1 Family Member, HLH-25. Raymarie Gomez-Vazquez, Casonya Johnson.

977A. Metallothionein transcriptional regulation, ROS and aging. J. Hall, JH Freedman.

978B. Function of the C. elegans T-box factor TBX-2 depends on SUMOylation. Paul Huber, Tanya Crum, Lynn Clary, Tom Ronan, Adelaide Packard, Peter Okkema.

979C. The role of C. elegans Histone H2A Variants in Transcription during Spermatogenesis. Londen C. Johnson, Liezl Madrona, Margaret Jow, Diana Chu.

980A. The homeobox transcription factors, CEH-14 and TTX-1 regulate the AFD neuron specific gene expression of gcy-8 and gcy-18 in C. elegans. Hiroshi Kagoshima, Yuji Kohara.

981B. Affecting gene expression through nucleosome positioning. Colton E. Kempton, Steven M. Johnson.

982C. Hunting for the causes of inter-individual variation in chaperone expression. Adam Klosin, Kadri Reis, Ben Lehner.

983A. Genetic analysis of pry-1/Axin regulation and Wnt signaling in nematode vulva development. Jessica Knox, Philip Cumbo, Bhagwati P. Gupta.

984B. Towards Unrestricted Direct Reprogramming: A genome-wide RNAi screen to identify cell fate reprogramming-inhibiting factors. Ena Kolundzic, Oktay Kaplan, Martina Hajduskova, Andreas Ofenbauer, Alina Schenk, Baris Tursun.

985C. X chromosome dosage compensation in the early C. elegans embryo. Maxwell Kramer, Sevinc Ercan.

986A. A quantitative system to define the role of transcription factor binding affinity in transcriptional activation. Brett Lancaster, James McGhee.

987B. C. elegans CCM-3 may affect excretory canal development through endosome recycling. Benjamin Lant, W. Brent Derry.

988C. In silico identification and functional analysis of genes responsive to dietary restriction in Caenorhabditis elegans . Andreas H. Ludewig, Meike Bruns, Maja Klapper, Thomas Meinel, Frank Doering.

989A. Altered-function mutations of the U2AF large subunit are protective modifiers of the C. elegans SMN mutant defects. X. Gao, L. Ma.

990B. An in vivo C. elegans gene regulatory network unveils post-developmental role of intestinal transcription factors. Lesley T. MacNeil, H. Efsun Arda, Lauren D'Elia, A. J. Marian Walhout.

991C. DBL-1 Target Gene Regulation By SMA-2, SMA-3, and SMA-4. Uday Madaan, Jianghua Yin, Edlira Yzeiraj, Cathy Savage-Dunn.

992A. The Receptor Tyrosine Phosphatase MOA-1 shows a temperature-dependent induction and affects C. elegans viability and development. Vanessa Marfil, Chris Li.

993B. Inverted repeat sequences required for alternative splicing of the unc-17 - cha-1 cholinergic locus. Ellie Mathews, Greg Mullen, Jim Rand.

994C. Poising and pausing of Pol II during starvation. Colin S. Maxwell, William S. Kruesi, Nicole Kurhanewicz, Leighton J. Core, Colin T. Waters, Caitlin L. Lewarch, Igor Antoshechkin, John T. Lis, Barbara J. Meyer, L. Ryan Baugh.

995A. Alternative 3’UTRs: A Mechanism for Post-transcriptional Regulation in C. elegans Germline and Early Embryo. D. Mecenas, R. Ahmed, M. Gutwein, J. Reboul, J. Polanowska, K. Gunsalus, F. Piano.

996B. In vivo spatiotemporal analysis of mRNA alternative splicing during C.elegans neural development. Jonathan R. M. Millet, Denis Dupuy.

997C. A high-throughput EMS screen to identify direct reprogramming regulating factors. Andreas Ofenbauer, Oktay Kaplan, Martina Hajduskova, Ena Kolundzic, Stefanie Seelk, Selman Bulut, Alina Schenk, Baris Tursun.

998A. A global genetic screen for the identification of factors involved in C. elegans spliced leader trans-splicing. L. Philippe, B. Connolly, B. Müller, J. Pettitt.

999B. LPR-1 facilitates LIN-3/EGF signaling during the development of the excretory system. Pu Pu, D. Freed, M. Lemmon, M. Sundaram.

1000C. In vivo reporters for spatiotemporal regulation of genes by microRNA. Cecile A. L. Quere, Denis Dupuy.

1001A. The transcriptional repressor CTBP-1 functions in the nervous system to regulate gene expression. Anna E. Reid, Duygu Yücel, Estelle Llamosas, Sashi Kant, Hannah Nicholas.

1002B. Complex expression dynamics and robustness in C. elegans insulin networks. Ashlyn D. Ritter, Yuan Shen, Juan Fuxman Bass, Sankarganesh Jeyaraj, Bart Deplancke, Arnab Mukhopadjay, Jian Xu, Monica Driscoll, Heidi Tissenbaum, A. J. Marian Walhout.

1003C. Uncovering genotype specific variation of Wnt signaling in C. elegans. M. Rodriguez, LB Snoek, T. Schmid, N. Samadi, L. van der Bent, A. Hajnal, JE Kammenga.

1004A. The sudden transcriptional switch to adulthood in L4 stage C. elegans. L. B. Snoek, M. G. Sterken, R. J. M. Volkers, M. Klatter, K. Bosman, R. P. J. Bevers, J. A. G. Riksen, J. E. Kammenga.

1005B. Toxicogenomic responses of Caenorhabditis elegans to silver nanomaterials. Daniel L. Starnes, C. Starnes, J. Smith, E. Oostveen, J. Unrine, B. Collin, P. Bertsch, O. Tsyusko.

1006C. Cadmium exposure affects insulin signaling in Caenorhabditis Elegans. Y. Sun, J. Freedman.

1007A. Ribosomal Protein L1 regulates alternative splicing of its own pre-mRNA. Satomi Takei, Hidehito Kuroyanagi.

1008B. High throughput EMS mutagenesis screen for cadmium response genes in C. elegans. Yong-Guang Tong, Jonathan H. Freedman.

1009C. In search of genes necessary for the identity or specification of the gonadal sheath. Laura G. Vallier.

1010A. Molecular genetic deciphering of the reproductive pathway in Caenorhabditis elegans. Liesbeth Van Rompay, Lotte Frooninckx, Isabel Beets, Liesbet Temmerman, Tom Janssen, Liliane Schoofs.

1011B. Exploring Gene Expression and Transcriptional Regulation Data in WormBase. Xiaodong Wang, Wen Chen, Daneila Raciti.

1012C. Determining the time and tissue specific expression of genes during embryogenesis. Adam D. Warner, Chau Huynh, Robert H. Waterston.

1013A. Identification of cis-regulatory elements that confer zinc-responsive transcription in intestinal cells of C. elegans. Hyun Cheol Roh, Ivan Dimitrov, Krupa Deshmukh, Guoyan Zhao, Kurt Warnhoff, Daniel Cabrera, Wendy Tsai, Kerry Kornfeld.

1014B. Integration of metabolic and gene regulatory networks governs the transcriptional response to diet in C. elegans. Emma Watson, Lesley MacNeil, H. Efsun Arda, Lihua Julie Zhu, Albertha J. M. Walhout.

1015C. Transcriptional regulation in the intestine. T. Wiesenfahrt, J. Berg, E. Osborne Nishimura, J. McGhee.

1016A. Phenotype analyses and expression of the sphingomyelin synthase genes in Caenorhabditis elegans. Haruka Yamaji, Yukako Tohsato, Kenji Suzuki, Masahiro Ito.

1017B. Investigating the expression and function of a C. elegans chemosensory receptor. Jinzi Yang, Harleen Basrai, Alisha Anderson, Stephen Trowell, Carolyn Behm.

1018C. Independent Regulation of Metabolism but Coordinated Control of Tissue Development by Epidermis Specific Proteins in Caenorhabditis elegans . Jiaofang Shao, Kan He, Hao Wang, Vincy Ho, Xiaoliang Ren, Xiaomeng An, Ming-Kin Wong, Bin Yan, Dongying Xie, John Stamatoyannopoulos, Zhongying Zhao.

1019A. Knock-down of nuclear pore subunit NPP-11 suppresses the germline apoptosis and differentiation defects of C41G7.3 mutants in C. elegans. Xue Zheng, Ataman Sendoel, Deni Subasic, Anneke Brümmer, Shivendra Kishore, Mihaela Zavolan, Michael Hengartner.

Gene Regulation and Genomics: RNA Interference and Small RNAs

1020B. Heat shock activates a miRNA-dependent response pathway in Caenorhabditis elegans. Antti P. Aalto, Ian A. Nicastro, Amy E. Pasquinelli.

1021C. Analysis of microRNA regulation of defecation behavior. Benedict J. Kemp, Adele Gordon, Carmela Rios, Megan Mohnen, Spencer Agnew, Julien Aoyama, Allison L. Abbott.

1022A. The Visual Detection of odr-1 22G RNAs via a MosSCI Sensor System. Adriel-John Ablaza, Bi-Tzen Juang, Noelle L'Etoile, Maria Gallegos.

1023B. CEY-1 attenuates let-7 microRNA-mediated silencing in C. elegans. Amelia F. Alessi, Vishal Khivansara, Sang Young Chun, James J. Moresco, John R. Yates III, John Kim.

1024C. LIN-28-dependent repression of let-7 miRNA is required for oogenesis. Yoshiki Andachi, Yuji Kohara.

1025A. Cytoplasmic versus nuclear RNAi mechanisms in transgene-induced gene silencing in Caenorhabditis elegans. Nadeem Asad, Laticia Rivera, Arthur Ankeney, Raeann Whitney, Lisa Timmons.

1026B. Identification of endogenous let-7 miRNA target sites by iCLIP. James P. Broughton, Michael T. Lovci, Gene W. Yeo, Amy E. Pasquinelli.

1027C. Mir-34 and mir-83 protect C. elegans gonad morphogenesis against temperature fluctuations. Samantha Burke, Molly Hammell, Victor Ambros.

1028A. Receptor of Activated C Kinase RACK-1 may regulate the Caenorhabditis elegans heterochronic gene pathway at the larva-to-adult transition. Shih-Peng Chan, Yu-De Chu, We-Chieh Wang, Shi-An Chen, Frank Slack.

1029B. Characterizing the individual roles of CSR-1 isoforms across development in Caenorhabditis elegans. V. H. W. Cheung, J. M. Claycomb.

1030C. An RNAi-based screen for the DExD/H-box RNA helicases involved in Caenorhabditis elegans microRNA function. Yu-De Chu, Tao Huang, Guan-Rong Chen, Shin-Kai Chen, Shih-Peng Chan.

1031A. Functional Characterization of the CSR-1 Small RNA Pathway in C. briggsae. Monica Wu, Jie Wang, Shikui Tu, Zhiping Weng, Julie M. Claycomb.

1032B. Identification of genes required for RNAi-mediated antiviral immunity by a genome-wide genetic screen in C. elegans. Stephanie R. Coffman, Yuanyuan Guo, Zhihuan Gao, Gina Broitman-Maduro, Morris Maduro, Shou-wei Ding.

1033C. NHL-2 Influences 22G RNAs to Maintain Germline Mediated Chromosomal Integrity. Gregory M. Davis, Wai Y. Low, Julie M. Claycomb, Peter R. Boag.

1034A. Identifying Zrt, Irt-like proteins that promote resistance to zinc toxicity in C. elegans. Nicholas K. Dietrich, Kerry Kornfeld.

1035B. Dissecting the role of NAP-1 in small RNA-mediated chromatin modulation. M. A. Francisco, J. M. Claycomb.

1036C. C. elegans as a model for fatty acid oxidation disorders. Wen Gao, Ronald J. Wanders, Riekelt H. Houtkooper.

1037A. The Virus Sensing Domains of RIG-I Functionally Replace the Corresponding Domains of DRH-1 in Antiviral RNA Silencing in Caenorhabditis elegans. Xunyang Guo, Rui Zhang, Jeffery Wang, Rui Lu.

1038B. Analysis of ok2951, a mutation found in F56D2.6, a putative homologue of the yeast PRP43 protein. Jonathan E. Karpel, Miranda Roland.

1039C. Direct Reprogramming of Distinct Cell Types in C. elegans into GABAergic Motor Neurons. Marlon Kazmierczak, Ena Kolundzic, Baris Tursun.

1040A. Investigating how an autoregulatory loop enhances let-7 biogenesis. Sarah A. Lima, Dimitrios G. Zisoulis, Zoya S. Kai, Vanessa Mondol, Amy E. Pasquinelli.

1041B. C. elegans RNA Helicase A genetically interacts with genes involved in two different germline RNAi pathways. Penelope L. Lindsay, Megan K. Gautier, Karen J. Muschler, Sarah K. O'Connor, Katherine M. Walstrom.

1042C. The mir-35 family of microRNAs regulates hermaphrodite fecundity, male development, and genetically interacts with the sex determination pathway. Katherine McJunkin, Victor Ambros.

1043A. Orsay virus replication kinetics in C. elegans strain Bristol N2. Mark G. Sterken, Kobus J. Bosman, L. Basten Snoek, Jikke Daamen, Joost A. G. Riksen, Jaap Bakker, Gorben P. Pijlman, Jan E. Kammenga.

1044B. Nicotine Exposed Chronically During the Post-embryonic Stages Systematically Altered the MicroRNA Expression Profiles in C. elegans. Faten A. Taki, Baohong Zhang.

1045C. TEG-1 regulates the stability of miRISC components and the levels of microRNAs. Chris Wang, Dave Hansen.

1046A. 3'LIFE: A functional assay to detect C. elegans miRNA targets in high-throughput. JM Wolter, K. Kotagama, AC Pierre-Bez, M. Firago, M. Tennant, M. Mangone.

1047B. Analysis of PUF-9 and miRNA interactions in C. elegans. Danny Yang, Sang Chun, Ting Han, James Moresco, John Yates III, John Kim.

1048C. The SNARE protein SEC-22 is a negative regulator of RNAi. Y. Zhao, B. Holmgren, A. Hinas.

Gene Regulation and Genomics: Genomics

1049A. The first 100 nematode genomes: towards a genomic biology of Nematoda. Mark L. Blaxter, Georgios Koutsovoulos, Sujai Kumar, Michael Clarke, Martin Jones, Alex Marshall, Benjamin Makepeace, Philipp Schiffer, Einhardt Schierenberg, Simon Babayan, Nick Gray.

1050B. 959.nematodegenomes.org. Mark L. Blaxter, Georgios Koutsovoulos, Sujai Kumar, Philipp Schiffer.

1051C. Advancing and Refining the C. elegans 3’UTRome. SM Blazie, AC Pierre-Bez, CE Otto, CA Lynch, M. Mangone.

1052A. A pair of RNA binding proteins shape alternative splicing regulatory networks in distinct neuronal subtypes. Adam D. Norris, Mei Zhen, John A. Calarco.

1053B. A genome-wide network of genetic interactions in embryonic development. Patricia G. Cipriani, Amelia White, Huey-Ling Kao, Eliana Munarriz, Katherine Erickson, Jessica Lucas, Indrani Chatterjee, Jerome Reboul, Kristin Gunsalus, Fabio Piano.

1054C. A draft genome assembly of Caenorhabditis sp. 9. and its use in characterizing genome shrinkage in self-fertile nematodes. Da Yin, Erich M. Schwarz, Caitlin M. Schartner, Edward J. Ralston, Barbara J. Meyer, Eric S. Haag.

1055A. Mapping transcriptional regulatory networks in the nematode Caenorhabditis elegans. Margaret Ho, Paul Sternberg.

1056B. Analysis of developmental RNA-Seq libraries reveals signature profile for cilia-related genes. Victor L. Jensen, Tiffany A. Timbers, Chunmei Li, Ryan D. Morin, Michel R. Leroux.

1057C. Characterisation of genomic instability and interstrand crosslink sensitivity associated with mutation of dog-1, the functional ortholog of human Fanconi Anemia protein FancJ. Martin R. Jones, Jeffrey S. Chu, Ann M. Rose.

1058A. Genome-wide binding characteristics of the dosage compensation complex in C. elegans. Anna-Lena Kranz, Chen-Yu Jiao, Lara Winterkorn, Sarah Albritton, Sevinç Ercan.

1059B. The use of C.elegans to identify novel mutations that confer benzimidazole resistance. Sharmilah L. J. Latheef, Susan S. Stasiuk, John S. Gilleard.

1060C. The involvement of the Caenorhabditis elegans EPE1 homolog in DNA interstrand crosslink repair. Sang-Yong An, Changrim Lee, Hyeon-Sook Koo.

1061A. Using Next-Generation Sequencing to Determine Gene Identity in Temperature-Sensitive, Embryonic Lethal Mutants. Josh Lowry, Amy Connolly, Bruce Bowerman.

1062B. Genomic analysis of Steinernema: Insights into insect parasitism, intragenus and intergenus evolution. Ali Mortazavi, Marissa Macchietto, Adler Dillman, Alicia Rogers, Brian Williams, Igor Antoshechkin, Camille Finlinson, Zane Goodwin, Xiaojun Lu, Patricia Stock, Edwin Lewis, Heidi Goodrich-Blair, Byron Adams, Paul Sternberg.

1063C. Selenocysteine incorporation in metazoa: the peculiar case of the nematode lineage. Lucía Otero, Laura Romanelli, Vadim N. Gladyshev, Antonio Miranda-Vizuete, Gustavo Salinas.

1064A. Molecular characterization of mitocycin C-induced lethal mutations in Caenorhabditis elegans. Annie Tam, Jeffrey SC. Chu, Ann M. Rose.

1065B. Combining genomic approaches to characterize alternative splicing events in C. elegans. June Tan, Arun Ramani, Hong Na, Debashish Ray, Timothy Hughes, Andrew Fraser.

1066C. Determining Fragile Nucleosome Distribution Bias Within the Chromosome. Ashley Wright, Steven Johnson.

1067A. Identification of Molecular Targets of the Antidiabetic Drug Metformin in C. elegans. Lianfeng Wu, Alexander Soukas.

Gene Regulation and Genomics: Epigenetics

1068B. Analysis of Histone methylation in germ cells using C. elegans as model system. Pier Giorgio Amendola, Toshia Myers, Anna Elisabetta Salcini.

1069C. Functional analysis of H3K79 methylation. Fanelie Bauer, Alex Appert, Julie Ahringer.

1070A. Roles of histone demethylation in germline maintenance. Sara E. Beese-Sims, Monica P. Colaiacovo.

1071B. Forward Genetic Screen for Induced Conversion of Germ Cells. Idris Selman Bulut, Oktay Ismail Kaplan, Baris Tursun.

1072C. O-GlcNAcylation of a conserved chromatin factor, ZFP-1(AF10), as a possible glucose-sensing mechanism. Ainhoa Ceballos, Germano Cecere, Daphne Avgousti, Grishok Alla.

1073A. “Who wants to live forever?”- chromatinome RNAi screen for longevity in C. elegans. Karolina Chocian, Hayley Lees, Helena Cantwell, Gino Poulin, Jane Mellor, Alison Woollard.

1074B. synMuv B regulation of chromatin states at high temperature. Meghan Elizabeth Costello, Andreas Rechtsteiner, Thea Egelhofer, Susan Strome, Lisa N. Petrella.

1075C. Epigenetic regulation of fertility in C. elegans males depends on the gamete source and chromatin history of the X chromosome. Laura Gaydos, Andreas Rechtsteiner, Wenchao Wang, Susan Strome.

1076A. CEC-4 is a novel chromodomain protein involved in perinuclear chromatin anchoring. Adriana V. Gonzalez Sandoval, Veronique Kalck, Benjamin D. Towbin, Teddy Yang, Kehao Zhao, Susan M. Gasser.

1077B. An extended RNAi sub-library to uncover chromatin factors implicated in direct cell-type conversion. M. Hajduskova, M. L. Beato del Rosal, E. Kolundzic, B. Tursun.

1078C. Nucleosome organization in C. elegans gamete chromatin. Tess E. Jeffers, Jason D. Lieb.

1079A. Conversion of epithelial cells into a neuron like cell in C. elegans. Oktay Ismail Kaplan, Idris Selman Bulut, Baris Tursun.

1080B. Examining the Role of Histone Acetyltransferases in Targeting the C. elegans DCC to the X Chromosomes. Alyssa C. Lau, Gyorgyi Csankovszki.

1081C. Dao-5/CeNopp140 modulates rDNA chromatin epigenetic status and transcription to sustain oogenesis. Chi-Chang Lee, Yi-Tzang Tsai, Li-Wei Lee, Chih-Wei Kao, Huey-Jen Lai, Tien-Hsiang Ma, Yu-Sun Chang, Ning-Hsin Yeh, Szecheng J. Lo.

1082A. Epigentic regulation of L1 longevity. Inhwan Lee, Young-jai You.

1083B. Spatial gene positioning in the Caenorhabditis elegans embryo. Darina Majovská, Christian Lanctôt.

1084C. Dynamics of nuclear compartments in C. elegans. Rahul Sharma, Georgina Gomez-Saldivar, Jop Kind, Bas van Steensel, Peter Askjaer, Peter Meister.

1085A. Towards understanding the role of histone demethylation in replication-induced DNA damage repair. Toshia Myers, Pier Giorgio Amendola, Anna Elisabetta Salcini.

1086B. The C. elegans acetylome identifies genes and molecular pathways involved in dopamine neuron vulnerability. Richard M. Nass, Jonathan Trinidad, Natalia VanDuyn.

1087C. Starving chromosome; reshaping the chromatin to survive. Ehsan Pourkarimi, Mark Larance, Angus Lamond, Anton Gartner.

1088A. usp-48 encodes a deubiquitinating enzyme involved in cell fate restriction during development. Dylan Rahe, Tulsi Patel, Oliver Hobert.

1089B. SET-2, ASH-2 and WDR-5 regulate distinct sets of genes in the C. elegans germline. Valérie J. P. Robert, Marine Mercier, Lucie Kozlowski, Cécile Bedet, Diyavarshini Gopaul, Stéphane Janczarski, Francesca Palladino.

1090C. The characterization of the histone-chaperone lin-53. Stefanie Seelk, Baris Tursun.

1091A. HTZ-1/H2A.z maintains cell fates through transcriptional repression in an H3K27me-independent manner. Yukimasa Shibata, Hitoshi Sawa, Kiyoji Nishiwaki.

1092B. Turnover of the H3K9me2 Mark During Late Spermatogenesis. Matthew P. Snyder, Xia Xu, Eleanor Maine.

1093C. Molecular Characterization of Epigenetic Inheritance Factors in C.elegans. G. Spracklin, S. Kennedy.

1094A. Expression of MET-2, a H3K9 methyltransferase, in the C. elegans germ line. Bing Yang, Xia Xu, Eleanor Maine.

Cell Biology: Cell Polarity and the Intracellular Trafficking

1095B. Using a glo-2 enhancer screen to investigate BLOC-1 function in protein trafficking to gut granules. Alec Barrett, Daniel Saxton, Greg Hermann.

1096C. The Caenorhabditis elegans UDP-Glc:glycoprotein glucosyltransferase homologue CeUGGT-2 is an essential protein that does not function as a glycoprotein conformation sensor. Lucila Buzzi, Sergio Simonetta, Armando Parodi, Olga Castro.

1097A. An RNAi screen for LRP-1 trafficking regulators reveals a role for EPN-1 epsin in endocytosis of LDL receptor superfamily. Yuan-Lin Kang, John Yochem, Leslie Bell, Erica Sorensen, Lihsia Chen, Sean Conner.

1098B. A microtubule minus-end binding protein and minus-end directed transport function in the C. elegans epidermis. Marian Chuang, Tiffany I. Hsiao, Amy Tong, Shaohe Wang, Karen Oegema, Andrew Chisholm.

1099C. Polarity proteins regulate the localization of a spindle-positioning mediator, LET-99. Eugenel B. Espiritu, Jui-Ching Wu, Kari Messina, Lesilee Rose.

1100A. Networks regulating pharyngeal development and morphogenesis. David S. Fay, Stanley Polley, Jujiao Kuang, Jon Karpel, Evguenia Karina, Aleksandra Kuzmanov, John Yochem.

1101B. Disparate endocytic recycling of the TGFβ signaling receptors, Sma-6 and Daf-4, regulates signaling of the Sma/Mab pathway. Ryan Gleason, Adenrele (Dee) Akintobi, Ying Li, Nanci Kane, Barth Grant, Richard Padgett.

1102C. The EXC-1 RAS-Domain Protein Mediates Vesicle Movement in the Excretory Canal. Kelly A. Grussendorf, Alexander T. Salem, Christopher J. Trezza, Matthew Buechner.

1103A. A screen for mislocalization of the LET-23 EGF receptor during vulval development. Andrea Haag, Juan M. Escobar Restrepo, Alex Hajnal.

1104B. Identification and characterization of conserved factors mediating gut granule protein trafficking. Greg Hermann, Jared Delahaye, Olvia Foster, Annalise Vine, Thomas Curtin.

1105C. C. elegans Rag genes are involved in endosome / lysosome biogenesis in a TORC1-independent fashion. K. Iki, Y. Ito, Y. Shimomura, H. Kajiho, M. Fukuyama, K. Kontani, T. Katada.

1106A. Identification of genes important for excretory system function and maintenance using Whole Genome Sequencing. Michelle Kanther, Jennifer Cohen, Jean Parry, Meera Sundaram.

1107B. Starvation-responsive behavioral plasticity is tuned by tubulin polyglutamylation in sensory cilia. Yoshishige Kimura, Alu Konno, Koji Tsutsumi, Saira Hameed, Mitsutoshi Setou.

1108C. Instructive polarization of early embryonic cells by the cadherin-catenin complex and the RhoGAP PAC-1. Diana Klompstra, Dorian Anderson, Jeremy Nance.

1109A. Unraveling the interactome underlying cell polarity. Thijs Koorman, Monique van der Voet, Sander van den Heuvel, Mike Boxem.

1110B. An ABC transporter regulates systemic heme homeostasis in C. elegans. Tamara Korolnek, Iqbal Hamza.

1111C. Regulation of TBC-2, an endosomal Rab5 GAP. Fiona Law, Laëtitia Chotard, Farhad Karbassi, Christian Rocheleau.

1112A. Depletion of mboa-7, an enzyme that incorporates polyunsaturated fatty acids into phosphatidylinositol (PI), impairs PI 3-phosphate signaling. Hyeon-Cheol Lee, Takuya Kubo, Nozomu Kono, Eriko Kage-Nakadai, Keiko Gengyo-Ando, Shohei Mitani, Takao Inoue, Hiroyuki Arai.

1113B. Suppressors of the pam-1 aminopeptidase and the role of centrosome-cortical contact in one-cell anteroposterior polarity. Margaret Williams, Ashley Kimble, Zachary Klock, Jessica Meeker, Kevin Kozub, Eva Jaeger, Rebecca Lyczak.

1114C. Sequential roles of Atg8 homologs during autophagosome formation. Marion Manil-Segalen, C. Lefebvre, C. Jenzer, C. Boulogne, B. Satiat-Jeunemaitre, V. Galy, R. Legouis.

1115A. LET-99 regulates G protein signaling and spindle positioning during asymmetric division. Jennifer A. Milan, Dae Hwi Park, Lesilee S. Rose.

1116B. Patched family member PTR-2 is required for permeability barrier formation in the C. elegans zygote. Jade P. X. Cheng, Sara K. Olson, Alexander Soloviev, Olivier Zugasti, Karen Oegema, Patricia E. Kuwabara.

1117C. Screen for endocytic genes required for dauer development and autophagy. Nicholas J. Palmisano, David Jimenez, Alicia Meléndez.

1118A. Role of fibroblast growth factor receptor in regulation of membrane traffic. Navin David Rathna Kumar, Zita Balklava.

1119B. Several ArfGEFs regulate the apoptotic fate in Q neuroblast asymmetric cell divisions. Jerome Teuliere, Shaun Cordes, Gian Garriga.

1120C. Regulatory effect of MAGUK/LIN-2 on kinesin-3-based transport in the neuronal system of C. elegans. Gong-Her Wu, Oliver Wagner.

1121A. VANG-1, one of the PCP core components, is involved in asymmetric divisions of seam cell. M. Yokoo, H. Sawa.

1122B. Amphiphysin 2 binds nesprin and regulates nuclear positioning. M. D'Alessandro, K. Hnia, C. Koch, C. Gavriilidis, S. Quintin, N. B. Romero, Y. Schwab, M. Labouesse, J. Laporte.

Cell Biology: Morphogenesis, Migration, Cytoskeleton

1123C. EXC-2 and Maintenance of excretory canal tube structure. Hikmat Al-Hashimi, Robyn Harte, Jenny Hackett, Stuart Macdonald, Matthew Buechner.

1124A. Microtubules and Fertilization: The Meiosis to Mitosis Transition. Sarah M. Beard, Ben G. Chan, Paul E. Mains.

1125B. The molecular genetics of epithelial cell morphogenesis- functional dissection of C. elegans homologue zyxin. Keliya Bai, Jonathan Pettitt.

1126C. Dissecting the mechanistic insights through which EGL-26 controls C. elegans vulva tubulogenesis. Nagagireesh Bojanala, Avni Upadhyay, Hongliu Sun, Matt Crook, Ariana Detwiler, Nishat Seraj, Sarah Chang, Jimmy Goncalves, Ryan Fine, Nick Serra, Wendy Hanna-Rose.

1127A. Characterizing regulators of the C. elegans embryonic elongation pathway. Benjamin Chan, Simon Rocheleau, Paul Mains.

1128B. The RhoGEF ECT-2 is Required for Ventral Enclosure During C. elegans Embryogenesis. Y. Chen, A. Marte, G. Stylianopoulos, A. Piekny.

1129C. The Regulation of Bone Morphogenetic Protein Pathway by LON-1 in Extracellular Matrix using a novel BMP readout. King-Lau Chow, Ho-Tsan Wong, Kwok-Hei Wong.

1130A. A genome-wide RNAi screen to identify new players of a muscle-to-epidermis mechanotransduction pathway essential for embryonic elongation. Christelle Gally, Agnès Aubry, Michel Labouesse.

1131B. Regulation of C. elegans MCAK by Aurora Kinase Phosphorylation. Xue Han, Martin Srayko.

1132C. Mechanisms of Sperm Competition in C. elegans. Jody Hansen, Daniela Chavez, Gillian Stanfield.

1133A. Actin-based cell motility in developing C. elegans: dissecting actin assembly factors. Svitlana Havrylenko, Philippe Noguera, Julie Plastino.

1134B. A heterogeneous mixture of F-Series prostaglandins promotes sperm guidance in the Caenorhabditis elegans reproductive tract. Hieu D. Hoang, Jeevan K. Prasain, Michael A. Miller.

1135C. Anatomic Expression of the Tubulin Superfamily. Daryl D. Hurd.

1136A. ROL-3, the ortholog of the human proto-oncogene ROS1, is required to orchestrate the morphogenesis and development of the seam syncytium and interacts with the Bicaudal-C homolog bcc-1. Martin R. Jones, Ann M. Rose, David L. Baillie.

1137B. A novel protein complex required for the collective migration of the male somatic gonad. Mihoko Kato, Tsui-Fen Chou, Collin Z. Yu, Wen Chen, Paul W. Sternberg.

1138C. The role of SYM-3 and SYM-4 in tissue integrity and organogenesis. Pushpa Khanal, John Yochem, Anna Justis, David Fay.

1139A. Molecular mechanism of egl-15/FGFR and ina-1/α-integrin in gland cell migration during the development of Caenorhabditis elegans pharynx. S. Kim, J. Kormish.

1140B. Using genetics and proteomics to identify substrates of a PP2A phosphatase required for mitotic spindle assembly. Karen I. Lange, Martin Srayko.

1141C. Identification of DMD-3 targets in the C. elegans male tail tip. H. Littleford, R. A. Herrera, K. Kiontke, A. Mason, J.-S. Yang, S. Ercan, D. Fitch.

1142A. Analysis of tissue-to-tissue signaling and its effects on cytoskeletal polarity during embryonic cell migrations. Sailaja Mandalapu, Martha Soto.

1143B. pix-1 differential expression along the anterio-posterior axis of the embryos controls early elongation in parallel to mel-11 and let-502 in Caenorhabditis elegans. Emmanuel Martin, Sharon Harel, Bernard Nkengfac, Karim Hamiche, Mathieu Neault, Sarah Jenna.

1144C. Three distinct Wnt signaling mechanisms act sequentially to position the migrating QR neuroblasts of C. elegans. Remco A. Mentink, Chung Y. Tang, Marco C. Betist, Hendrik C. Korswagen.

1145A. “Ultrastructure analysis of the sarcomeres in worms that lack Z-line formins”. Lei Mi-Mi, David Pruyne.

1146B. dpy-19 and mig-21 control the persistent directionality of migrating Q neuroblasts in Caenorhabditis elegans. Teije C. Middelkoop, Thijs Koorman, Mike Boxem, Hendrik C. Korswagen.

1147C. The role of LIN-3 during morphogenesis of the dorsal lumen in the vulva. Louisa Mueller, Matthias Morf, Alex Hajnal.

1148A. Analysis of novel pathways for nuclear migration in C. elegans. Shaun P. Murphy, Yu-Tai Chang, Daniel A. Starr.

1149B. Mitochondria-type GPAT is required for mitochondrial fusion. Y. Ohba, T. Inoue, T. Sakuragi, N. H.Tomioka, A. Inoue, N. Ishihara, J. Aoki, E. Kage-Nakadai, S. Mitani, H. Arai.

1150C. Genomic analysis of the duct and pore cells reveals novel effectors and regulators of morphogenesis. Gregory Osborn, Travis Walton, Meera Sundaram, John Murray.

1151A. What is tubulin glutamylation good for? Nina Peel, Zach Barth, Ruchi Shah, Jessica Lee, Kevin O'Connell.

1152B. The in vivo Dynamics of IFT Motors and Axoneme Microtubules in Cilia Signaling. Jay Pieczynski, Patrick Hu, Kristen Verhey.

1153C. The Secretory Protein Calcium ATPase PMR-1 is essential for cell migration during gastrulation. V. Praitis, J. Simske, S. Kniss, R. Mandt, L. Imlay, C. Feddersen, M. B. Miller, J. Mushi, W. Liszewski, R. Weinstein, A. Chakravorty, D.-G. Ha, A. Schacht Farrell, A. Sullivan-Wilson, T. Stock.

1154A. LAWD-1, a potential scaffold protein with a WD40 domain involved in epithelial morphogenesis. Mengmeng Qiao, Jonathan Hodgkin, Patricia Kuwabara.

1155B. Structure-function analysis of the cell-fusion protein EFF-1. Hadas Raveh-Barak, C. Valansi, O. Avinoam, T. Krey, J. Perez-Vargas, FA. Rey, B. Podbilewicz.

1156C. Formins Play a Role in the C. elegans Embryonic Elongation. Osama M. Refai, Christopher A. Vanneste, David Pruyne, Paul E. Mains.

1157A. Towards the Complete Embryonic Cell Lineage. Anthony Santella, Zhuo Du, Zidong Yu, Yicong Wu, Hari Shroff, Zhirong Bao.

1158B. A Complex Issue: Understanding vMSP Receptor Heteromeric Complexing Behavior. Jessica L. Schultz, Sung Min Han, Se-Jin Lee, Michael Miller.

1159C. DBL-1 TGF-β localization and the physiological basis of body size regulation in C. elegans. Robbie D. Schultz, E. Ann Ellis, Tina L. Gumienny.

1160A. An In Vivo Analysis of Critical Functional Domains of α-catenin in C. elegans. Xiangqiang Shao, Jeffrey Simske, Anjon Audhya, Jeff Hardin.

1161B. LET-653, a secreted ZP-domain and mucin-related protein, functions in the excretory duct/pore, and not the excretory canal cell. Corey Poggioli, Kevin Bickard, Meera V. Sundaram.

1162C. SPV-1, a RhoGAP and F-BAR domain protein, regulates spermatheca contractility. Pei Yi Tan, Ronen Zaidel-Bar.

1163A. Regulation of the cadherin-catenin complex by the ULP-2 SUMO protease. Assaf Tsur, Ulrike Bening-Abu-Shach, Orit Adir, Limor Broday.

1164B. UNC-54 and Y54E5B.2 work in concert to inhibit ectopic membrane extensions away from the nerve cord in C. elegans body wall muscle. Ryan Viveiros, Ralf Schnabel, Robert Barstead, Donald Moerman.

1165C. Mechanical forces in C. elegans embryo elongation. Thanh TK Vuong, Michel Labouesse.

1166A. NOCA-1 isoforms regulate non-centrosomal microtubule array formation in different C. elegans tissues. Shaohe Wang, Arshad Desai, Karen Oegema.

1167B. Searching for regulators of LIT-1 localization in the amphid sensory compartment. Wendy M. Wang, Shai Shaham.

1168C. LIN-29/EGR1, a zinc-finger transcription factor, controls the depth of anchor cell invasion in C. elegans. Zheng Wang, Shelly McClatchey, Lara Linden, Qiuyi Chi, David Sherwood.

1169A. Anillin non-autonomously regulates epidermal morphogenesis during C. elegans embryogenesis. Wernike D., Fotopoulos N., Piekny A.

1170B. FAX-1 and PROMININ function in migration and morphogenesis. Bruce Wightman, Emily Bayer.

1171C. DYF-7 prevents rupture of a sensory epithelium made of neurons and glia. Claire R. Williams, Maxwell G. Heiman.

1172A. Role of integrin in neuronal cell migration. Jing Wu, Richa Manglorkar, Myeongwoo Lee.

1173B. The Ezrin/Radixin/Moesin protein ERM-1 controls actin-mediated cell shape changes during vulval invagination. Qiutan Yang, Juan Restrepo, Alex Hajnal.

Cell Biology: Cell Division and Chromosome Dynamics

1174C. Study of Aurora-B Kinase Regulators in C. elegans Meiosis. Elisabeth Altendorfer, Saravanapriah Nadarajan, Monica Colaiacovo.

1175A. MAIN CHROMOSOME ABERRATIONS FOUND AMONG 4617 PEDIATRIC PATIENTS AT A TIRHD LEVEL CHILDREN MEXICAN HOSPITAL. Juan M. Aparicio, Maria de L. Hurtado H., Margarita Barrientos P., Hortencia Chavez O., Sergio Chatelain M.

1176B. Spindle assembly checkpoint proteins regulate and monitor meiotic synapsis in C. elegans. T. Bohr, P. Lamelza, N. Bhalla.

1177C. Characterization and comparative profiling of the mitotic spindle proteome reveals a glycosylation factor, OSTD-1 as being necessary for cell division and ER morphology. Mary Kate Bonner, Ahna Skop.

1178A. SMCL-1 interacts with condensin proteins and modulates their function in chromosome dynamics. Lucy Fang-I Chao, Meha Singh, John Yates III, Kirsten Hagstrom.

1179B. Suppressor mutations for the CAND-1 regulator of cullin-RING ubiquitin ligases. Snehal N. Chaudhari, Edward T. Kipreos.

1180C. Investigating loss-of-function suppressors of C. elegans centrosomal defective mutants. Chien-Hui Chuang, Sean O'Rourke, Bruce Bowerman.

1181A. CHL-1 is required for DNA replicative integrity in Caenorhabditis elegans. George Chung, Ann M. Rose.

1182B. PP1 phosphatases, GSP-3 and GSP-4, are required for chromosome segregation in sperm meiosis. Thais G. Cintra, Joseph Beyene, Jui-Ching Wu, Diana Chu.

1183C. Oocyte meiotic spindle assembly. Amy Connolly, Valerie Osterberg, Sara Christensen, Chenggang Lu, Kathy Chicas-Cruz, Shawn Lockery, Paul Mains, Bruce Bowerman.

1184A. Dissection of the temporal requirements for cell division proteins. Tim Davies, Shawn Jordan, Vandana Chand, Kimberley Laband, Mimi Shirasu-Hiza, Julien Dumont, Julie Canman.

1185B. Developmental regulation of telomere anchoring in C. elegans. Helder C. Ferreira, Benjamin Towbin, Thibaud Jegou, Susan M. Gasser.

1186C. Characterizing the role of ATX-2, the C. elegans ortholog of Ataxin-2, in cell division. Megan Gnazzo, Ahna Skop.

1187A. Transcriptional Regulation of Centrosome Duplication in C. elegans. Jacqueline Goeres, Kevin O'Connell.

1188B. Functional dissection of MEL-28, a chromatin-binding protein with essential roles in nuclear envelope function and chromosome segregation. Georgina Gómez-Saldivar, Anita G. Fernandez, Allison Lai, Carly Bock, Cristina González-Aguilera, Fabio Piano, Peter Askjaer.

1189C. ZTF-15 is required for the meiotic synapsis checkpoint in C. elegans. Tom Hwang, Matt Ragle, Needhi Bhalla.

1190A. Intertwined Functions of Separase and Caspase in Chromosome Separation and Programmed Cell Death. Pan-Young Jeong, Ashish Kumar, Pradeep Joshi, Joel H. Rothman.

1191B. Systematic characterization and positional cloning of temperature-sensitive, embryonic-lethal C. elegans mutants. Reza Keikhaee, Chien-Hui Chiang, Amy Connolly, Josh Lowry, John Yochem, Bruce Bowerman.

1192C. Condensin depletion licenses an alternate meiotic DSB repair pathway. Teresa W. Lee, Barbara J. Meyer.

1193A. Suppression of Cell Cycle Defects through Knockdown of Tumor Suppressor Genes. Y. Liu, D. Tobin, M. Saito.

1194B. Cell cycle uncoupling and centriole elimination in the endoreduplicating intestinal cells of C. elegans. Yu Lu, Richard Roy.

1195C. A forward genetic screen for suppressors of an allele of microtubule-bundling factor, spd-1, crucial for central spindle formation during cytokinesis. E. Pablo-Hernando, B. Esmaeili, M. Mishima.

1196A. Methods to Study Toxic Transgenes: Analysis of Protease-Dead Separase in Membrane Trafficking. Diana Mitchell, Lindsey Uehlein, Joshua Bembenek.

1197B. The nuclear envelope protein LEM-2 is critical for nuclear positioning and centrosome attachment. Adela Morales Martinez, Agnieszka Dobrzynska, Cristina Ayuso, Peter Askjaer.

1198C. Mechanistic Insights Into The Recruitment of the Spindle Checkpoint Protein MDF-1 To Unattached Kinetochores. Mark Moyle, Karen Oegema, Arshad Desai.

1199A. Regulation of meiotic recombination by the MAP kinase cascade. Christian R. Nelson, Tom Hwang, Needhi Bhalla.

1200B. Centriole Copy Number Control Is Mediated by Protein Phosphatase 1-Beta in C. elegans. Nina Peel, Jyoti Iyer, Michael Dougherty, Kevin O'Connell.

1201C. The NR4A Orphan Nuclear Receptor NHR-6 Plays an Important Role in Cell Cycle Progression and Cell Differentiation during Spermatheca Development. Brandon Praslicka, Chris R. Gissendanner.

1202A. Evolutionary comparisons reveal a positional switch for spindle pole oscillation, and divergent regulation of GPR in Cænorhabditis embryos. Soizic Riche, Melissa Zouak, Françoise Argoul, Alain Arnéodo, Jacques Pécréaux, Marie Delattre.

1203B. Chromosome bi-orientation in the first spermatocyte meiotic division prevents abnormal spindle organization in the second division. Mara Schvarzstein, Anne Villeneuve.

1204C. Are there changes in nucleo-cytoplasmic volume ratio during early embryonic development of Caenorhabditis elegans? Jitka Simandlová, Christian Lanctôt.

1205A. RNA-binding Protein ATX-2 Interacts with SZY-20 to Regulate Centrosome Assembly in C. elegans Embryos. Michael Bobian, Madeline Topitzes, John Ross, Jake Crumb, Abigail Meisel, Dongyan Zhang, Mi Hye Song.

1206B. Characterization of lin-5 mRNA localization in the early embryo. Zoltán Spiró, Pierre Gönczy.

1207C. Identification and characterization of mel-43, a gene required for the meiosis-to-mitosis transition in C. elegans. Maryam Ataeian, J. Tegha-Dunghu, Martin Srayko.

1208A. Critical targets of CYD-1/CDK-4 in the control of cell cycle entry. Inge The, Suzan Ruijtenberg, Javier Muñoz, Martine Prinsen, Albert Heck, Sander van den Heuvel.

1209B. The C. elegans UBE2Q2 homolog, UBC-25, Promotes Cell Cycle Quiescence by Inhibiting Cyclin E Expression. David V. Tobin, Sarah H. Roy, Nadin Memar, Barbara Conradt, R. Mako Saito.

1210C. A splice mutation in pat-3 β integrin reveals genetic interactions between the extracellular matrix and cki-1/p27^KIP1. Eun-Jeong Yu, Lena Al-Rashed, Myeongwoo Lee.

1211A. The lipid binding and GAP domains of CYK-4 are essential for cytokinesis. Donglei Zhang, Andy Loria, Michael Glotzer.

Methods and Technology: Genetics

1212B. Efficient single-cell transgene induction in Caenorhabditis elegans using a pulsed infrared laser. Matthew A. Churgin, Liping He, John I. Murray, Christopher Fang-Yen.

1213C. A Functional Genomic Screen for the Telomerase RNA in C. elegans. Robert D. Cohen, Christopher Smith, Diana Chu.

1214A. Exploring the role of mechanosensory extracellular matrix components in the structure and function of primary cilia. Deanna Michele De Vore, Karla Knobel, Maureen Barr.

1215B. Study of arrhythmogenic mutations in the pharynx using electrophysiological and optogenetic approaches. E. Fischer, C. Schüler, S. Wabnig, K. Erbguth, P. Hegemann, L. L. Looger, A. Gottschalk.

1216C. MiniMos and Universal MosSCI sites - new methods for C. elegans transgenesis. C. Frokjaer-Jensen, MW Davis, M. Sarov, X. Liu, K. Rebora, J. Taylor, S. Flibotte, A. Pozniakovski, SK Kim, D. Dupuy, DG Moerman, EM Jorgensen.

1217A. A conditional knockout system based on the single/low-copy integration of transgenes in C. elegans. E. Kage-Nakadai, R. Imae, O. Funatsu, S. Hori, Y. Suehiro, S. Yoshina, S. Mitani.

1218B. Developing a high-throughput approach for identifying genetic interactions in C. elegans. Calvin A. Mok, O. A. Thompson, M. Edgley, L. Gevirtzman, C. Huynh, D. G. Moerman, R. H. Waterston.

1219C. Systematic comparison of bacterial feeding strains for increased yield of C. elegans males by RNA interference induced non-disjunction. Vaishnavi Nagarajan, Nadeem Asad, Hayley Luna, Jordan Martinez, Zachary Moore, Lisa Timmons.

1220A. Characterization of the hmgr-1 mutant, which lacks the C. elegans Homolog of HMG-CoA reductase. Parmida Ranji, Marc Pilon.

1221B. Expanding the repertoire of mutations amenable to identification by whole-genome sequencing. Sijung Yun, Michael Krause, Harold E. Smith.

1222C. Acute, High-throughput RNAi in C. elegans. Elizabeth J. Thatcher, Victor Ambros.

1223A. Genomic variation data in WormBase. Mary-Ann Tuli, Paul Davis, Michael Paulini, Gary Williams, Kevin Howe.

Methods and Technology: Imaging

1224B. A cGMP reporter for C. elegans. Mary Bethke, Chantal Brüggemann, O. Scott Hamilton, Damien O'Halloran, Bi-Tzen Juang, Klaus Kruttwig, Ben Barsi-Rhyne, Mihn Pham, Dominique Glauser, Miriam Goodman, Piali Sengupta, Miri Van Hoven, Noelle L'Etoile.

1225C. Endrov, a general imaging framework, to visualize C. elegans gene expression, 4D models, and lineage. Johan Henriksson, Jurgen Hench, Martin Luppert, Akram Abou-Zied, Lois Tang, Yong-Guang Tong, David Baillie, Thomas R. Burglin.

1226A. A non-trapping method for live imaging of specific neuronal connections. Muriel Desbois, Hannes Buelow.

1227B. In vivo calcium imaging of motor circuit during spontaneous locomotion using improved G-CaMPs. K. Gengyo-Ando, Y. Kagawa-Nagamura, M. Ohkura, X. Fei, M. Suzuki, K. Hashimoto, J. Nakai.

1228C. Mapping the entire connectome of C. elegans L1 larvae. Valeriya Laskova, Quan Wen, Richard Shalek, Daniel Berger, Maria Lim, Bobby Kasthuri, Verena Kaynig-Fittkau, Hanspeter Pfister, Jeff Lichtman, Aravi Samuel, Mei Zhen, Sihui Guan.

1229A. Development of a comprehensive image analysis software package for the analysis of lifespan, locomotion, body length, and egg laying of C. elegans. S. K. Jung, B. Aleman-Meza, C. M. Riepe, W. Zhong.

1230B. WormView: a library of modular Matlab functions for static and dynamic image analysis. Gunnar Kleemann, Lance Parsons, Coleen Murphy.

1231C. Development and applications of TEM approaches adapted for C. elegans research. Irina Kolotueva.

1232A. Probing intercellular lipoprotein transport in Caenorhabditis elegans by fluorescent nanodiamond imaging. Yung Kuo, Tsung-Yuan Hsu, Yi-Chun Wu, Huan-Cheng Chang.

1233B. 3-D Worm Tracker for C. elegans. Namseop Kwon, Ara B. Hwang, Seung-Jae Lee, Jung Ho Je.

1234C. WormSizer: Image-based analysis of nematode size and shape. Brad T. Moore, James M. Jordan, L. Ryan Baugh.

1235A. Investigation of Simplified Dual-fluorophore Dissecting Stereomicroscopes. Andy Papp, Chris Aldrich.

1236B. High-throughput approaches to motility analysis in C. elegans and parasitic nematodes. Frederick A. Partridge, David B. Sattelle.

1237C. C. elegans imaging by combined, selective plane illumination microscopy and optical projection tomography in a microfluidic device. M. Rieckher, G. Zacharakis, J. Ripoll, N. Tavernarakis.

1238A. High-throughput behavioral imaging reveals the neurons responsible for mechanosensory memory in C. elegans. Takuma Sugi.

1239B. Imaging lipid depositions with third harmonic generation microscopy. George Tserevelakis, Evgenia Megalou, George Filippidis, Barbara Petanidou, Costas Fotakis, Nektarios Tavernarakis.

1240C. High-speed, high-magnification tracking system for calcium imaging of neurite during free moving. Y. Tsukada, C. Min, X. Fei, K. Hashimoto, I. Mori.

1241A. DiSPIM: time to leave your confocal behind. Hari Shroff, Yicong Wu, Peter Wawrzusin, Justin Senseney, Robert Fischer, Ryan Christensen, Anthony Santella, Andrew York, Peter Winter, Clare Waterman, Zhirong Bao, Daniel Colón-Ramos, Matthew McAuliffe.

1242B. Lipid droplets distribution in different developmental stages of C. elegans by using Coherent Anti-stoke Raman Scattering (CARS) microscopy. Yung-Hsiang Yi, Cheng-Hao Chien, Wei-Wen Chen, Tian-Hsiang Ma, Kuan-yu Liu, Yu-sun Chang, Ta-Chau Chang, Szecheng J. Lo.

1243C. Towards correlated localization of synaptic proteins at light and electron microscopy using a new generation of quantum dots. Hong Zhan, Michel Nasilowski, Bénoît Dubertret, Christian Stigloher, Jean-Louis Bessereau.

1244A. Robust Head Versus Tail Determination to Facilitate High Throughput Image Processing and Automation Techniques in Caenorhabditis elegans. Mei Zhan, Hang Lu.

Methods and Technology: Gene Expression Profiling and ChIP

1245B. BLIND CEL-Seq: Employing multiplexed single-cell transcriptomics for high-resolution developmental time courses. Leon Anavy, Michal Levin, Sally Khair, Tamar Hashimshony, Itai Yanai.

1246C. Cell type-specific profiling of the transcriptome in Caenorhabditis elegans. Meenakshi K. Doma, Igor Antoshechkin, Paul W. Sternberg.

1247A. A high-throughput mechanism-based toxicity screen using C. elegans. RB Goldsmith, JR Pirone, WA Boyd, MV Smith, JH Freedman.

1248B. 3’ End Profiling of Gametogenesis in C. elegans Using RNA-Seq. Michelle Gutwein, Desirea Mecenas, Rina Ahmed, Paul Scheid, Fabio Piano, Kris Gunsalus.

1249C. Ecotoxicity of anatase and rutile TiO2 nanoparticles on C. elegans in dark condition. Chun-Chih Hu, Gong-Her Wu, Hsieh-Ting Wu, Oliver I. Wagner, Ta-Jen Yen.

1250A. Synchronization of C. elegans embryos. Olga Minkina, Megan Senchuk, Susan Mango.

1251B. Ribosome profiling reveals features of C. elegans longevity. Kristan K. Steffen, Andrew Dillin.

Methods and Technology: Proteomics and Metabolomics

1252C. Conserved ion and amino acid transporters identified as phosphorylcholine modified N-glycoproteins by metabolic labeling with propargylcholine in Caenorhabditis elegans. Casey Snodgrass, Amanda Burnham-Marusich, John Meteer, Patricia M. Berninsone.

1253A. Analysis of protein-protein interaction by in vivo quantitative proteomics during C. elegans embryogenesis. Jia-Xuan Chen, Florian E. Paul, Miyeko Mana, Kris Gunsalus, Fabio Piano, Matthias Selbach.

1254B. Quantitative identifications of temperature-sensitive gene product by using proteomic analysis. Narumi Enna, Kanami Monobe, Yusuke Ishido, Yukako Tohsato, Toshiya Hayano, Masahiro Ito.

1255C. Comparative proteomics and transcriptomics in two C. elegans wild-type strains. Polina Kamkina, Michael Daube, Bernd Roschitzki, Jonas Grossmann, Rita Volkers, Basten Snoek, Jan Kammenga, Sabine Schrimpf, Michael Hengartner.

1256A. Studying the effect of natural variation on protein abundance in C. elegans. Kapil Dev Singh, Polina Kamkina, Bernd Roschitzki, Mark Elvin, Miriam Rodriguez, Gino Poulin, L. Basten Snoek, Jan Kammenga, Sabine Schrimpf, Michael Hengartner.

1257B. in vivo isolation of telomeric proteins in the nematode Caenorhabditis elegans. Sanghyun Sung, Beomseok Seo, Junho Lee.

1258C. C. elegans metabolomics as a strategy in the fight against neurodegenerative diseases. Liesbet Temmerman, Roel Van Assche, Bart P. Braeckman, Ute Roessner, Liliane Schoofs.

1259A. Tissue-specific purification of protein complexes in C. elegans. S. Waaijers, A. D. Zoumaro-Djayoon, S. Goerdayal, J. Muñoz, A. J. Heck, M. Boxem.

1260B. Analysis of immunogenic proteins in C. elegans (V). A. Yamakawa, K. Susaki, Kei Onishi, H. Moriwaki, A. Aota, Y. Hashizume.

1261C. Cell type-specific proteomic profiling in Caenorhabditis elegans. Kai P. Yuet, Meenakshi K. Doma, John T. Ngo, Paul W. Sternberg, David A. Tirrell.

Methods and Technology: Databases and Programs

1262A. Easy access to modENCODE data. sergio contrino, Marc Perry, Fengyuan Hu, Ellen Kephart, Paul Lloyd, Rachel Lyne, Peter Ruzanov, Richard Smith, E. O. Stinson, Quang Trinh, Nicole Washington, Zheng Zha, Daniela Butano, Adrian Carr, Kim Rutherford, Seth Carbon, Sheldon McKay, Suzanna Lewis, Gos Micklem, Lincoln Stein.

1263B. Textpresso for C. elegans and Nematode. James Done, Yuling Li, Hans-Michael Müller, Paul Sternberg.

1264C. CisOrtho V 2.0: a comparative genomic approach to genome wide identification of transcription factor target genes. Lori Glenwinkel, Oliver Hobert.

1265A. GExplore updated: more genome-scale data mining for worm researchers. Jinkyo Suh, Harald Hutter.

1266B. Gene Function (and Gene Dysfunction) Data in WormBase: Where and How to Find It. Ranjana Kishore, Kimberly Van Auken, Raymond Lee, Gary Schindelman, Karen Yook, WormBase Consortium.

1267C. WDDD: Worm Developmental Dynamics Database. Koji Kyoda, Hatsumi Okada, Tomoko Sugimoto, Kenichi Henmi, Shihoko Yashiro, Shuichi Onami.

1268A. Simulation of embryonic development in C. elegans using agent-based modeling. William Decker, Josephine Cromartie, Daniel Brandon, Matthew O. Ward, Elizabeth F. Ryder.

1269B. A method of estimating environmental friction based on a body dynamics model of Caenorhabditis elegans. Zu Soh, Kazuya Masaoka, Michiyo Suzuki, Yuya Hattori, Toshio Tsuji.

1270C. Cell-level modeling and simulation of the pharyngeal pumping in Caenorhabditis elegans. Yuya Hattori, Michiyo Suzuki, Toshio Tsuji, Yasuhiko Kobayashi.

1271A. Visualizing Interactions and Pathways in WormBase. Karen J. Yook, Christian A. Grove, The WormBase Consortium.

Methods and Technology: Microfluidics and Neural Methods

1272B. Multi-well arrays for massively parallel cultivation and imaging of C. elegans. Matt Churgin, Chih-Chieh (Jay) Yu, Chris Fang-Yen.

1273C. An Automated Microfluidic Multiplexer for Fast Delivery of C. elegans Populations from Multiwells. Navid Ghorashian, Sertan Gökçe, Sam Guo, William Everett, Adela Ben-Yakar.

1274A. Microfluidic devices for longitudinal imaging of gently immobilized worms and live imaging of early embryos during acute drug treatment. Edgar Gutierrez, Rebecca Green, Sandra Encalada, Karen Oegema, Alex Groisman.

1275B. Electrical recordings of naturalistic feeding behavior in a microfluidic environment. Abraham W. Katzen, Shawn R. Lockery.

1276C. Durable interrogation of response and adaptation in Caenorhabditis elegans. Ronen B. Kopito, Erel Levine.

1277A. Design of the microchip device to dissect the neural circuit based on thermotactic behavior in C. elegans. Y. Nishida, M. Nakajima, J. Jaehoon, M. Takeuchi, K. Kobayashi, T. Fukuda, I. Mori.

1278B. Automated Suppressor Screen of Motor Degeneration Mutants Enabled by Microfluidics and Image Analysis. Ivan Cáceres, Daniel Porto, Ivan Gallotta, Josue Rodríguez-Cordero, Elia Di Schiavi, Hang Lu.

1279C. New high throughput analysis and redistribution technology for C.elegans to and from multiwell plates. Rock Pulak, Weon Bae, Bruce Holcombe, Mariya Lomakina, Mikalai Malinouski, Tom Mullins, Julia Thompson.

1280A. Phenotypic profiling of synaptic sites for subtle mutant identification in automated genetic screens. Adriana San Miguel, Matthew Crane, Peri Kurshan, Kang Shen, Hang Lu.

1281B. Pilot screening of phototoxicity of dyes by means of an automated motility bioassay using Caenorhabditis elegans. Javier I. Bianchi, Juan C. Stockert, Lucila Buzzi, Alfonso Blázquez-Castro, Sergio H. Simonetta.

1282C. A virtual reality running machine for worms-a highly integrated microscope system for olfactory behavior. Yuki Tanimoto, Kosuke Fujita, Yuya Kawazoe, Yosuke Miyanishi, Shuhei Yamazaki, Xianfeng Fei, Karl Emanuel Busch, Keiko Gengyo-Ando, Junichi Nakai, Koichi Hashimoto, Kotaro Kimura.

1283A. Chemical screens for factors affecting neuronal signaling using a semi-automated microfluidic electrotaxis platform. J. Tong, S. Salam, P. Rezai, R. K. Mishra, P. R. Selvaganapathy, B. P. Gupta.

1284B. New Computational Techniques for Automated Mutant Sorting, and an Application to the Identification of Synaptic Mutants in C. elegans. Charles L. Zhao, Ria Lim, Mei Zhen, Hang Lu.

1285C. Acute inhibition of synaptic transmission using Mini-Singlet Oxygen-Generator (miniSOG)-mediated protein ablation. Keming Zhou, Yishi Jin.

Methods and Technology: Other Nematodes

1286A. Leveraging C. elegans cue-dependent behaviour to understand the host/parasite interaction for plant parasitic nematodes. Anna Crisford, Jessica Marvin, James Kearn, Vincent O'Connor, Peter E. Urwin, Catherine Lilley, Lindy Holden-Dye.

1287B. Structure of a plant peptide hormone and a root-knot nematode-encoded mimic. Peter DiGennaro, Benjamin Bobay, Elizabeth Scholl, Nijat Imin, Michael Djordjevic, David Mck. Bird.

1288C. Treat worm infections with crystal protein expressing in probiotic like bacteria. Yan Hu, Melanie Miller, Alan Derman, Brian Ellis, Daniel Huerta, Joseph Pogliano, Raffi Aroian.

1289A. Development of quantitative methods for assessing the effects of anthelmintics on parasitic nematodes (soil transmitted helminths). Melanie M. Miller, Linda Z. Shi, Yan Hu, Arash Safavi, Sandy Chang, Michael Berns, Raffi V. Aroian.

1290B. another can of worms - more genomes and sequences at WormBase. Michael Paulini, Paul Davis, Mary Ann Tuli, Gareth Williams, Kevin Howe.

1291C. C. briggsae genomic fosmid library. Mathew Tinney, Elisabeth Loester, Susanne Ernst, Siegfried Schloissnig, Andreas Dahl, Mihail Sarov.

1292A. Genome and transcriptome of the zoonotic hookworm Ancylostoma ceylanicum. Erich M. Schwarz, Yan Hu, Igor Antoshechkin, Paul W. Sternberg, Raffi V. Aroian.

1293B. C. elegans as an expression system for drug targets from parasitic nematodes. Megan. A. Sloan, Barbara. J. Reaves, Adrian. J. Wolstenholme.

1294C. Worms in dirt: nematode diversity in restored tallgrass prairie. Breanna Tetreault, Andrea K. Kalis, Jennifer Ross Wolff.

Academic Teaching

1295A. Spectrum: Building Pathways to Biomedical Research Careers for Girls and Women of Color. Diana S. Chu, Audrey G. Parangan-Smith, Kimberly D. Tanner.

1296B. C. elegans modules for multiple laboratory classes. Janet S. Duerr.

1297C. A semester-long investigative lab provides an authentic research experience in the cell biology of C. elegans embryos. Sara K. Olson, David Morgens.

1298A. A continuous, discovery-based C. elegans laboratory for an intermediate-level undergraduate molecular and cellular biology course. Yan Qi, Jill Penn, Rachelle Gaudet.

1299B. FIRE lab (Full Immersion Research Experience): Student-directed projects on ALA-dependent sleep in C. elegans. Cheryl Van Buskirk, Dany Roman, BIOL447/L students.

Important Dates

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