Poster Session Listing
Physiology: Aging and stress
The Caenorhabditis elegans WRN-1 RecQ helicase participates in both DNA damage signaling and DNA Repair. Byungchan Ahn, M. Hyun, S. Park, E. Kim, H. Park.
Amyloid-binding compounds extend lifespan in C. elegans. Silvestre Alavez, Maithili C. Vantipalli, David J. S. Zucker, Ida M. Klang, Gordon J. Lithgow.
The role of the sumoylation pathway in the regulation of protein synthesis during ageing. Artemisia Andreou, Nektarios Tavernarakis.
5' Fluorourdine (FUDR) is protective against stress and aggregation-related disease phenotypes. Suzanne Angeli, David Zucker, Ida Klang, Pedro Rodrigues, Karla Mark, Gordon Lithgow, Julie Andersen.
Why do elevated levels of the SOD-1 cytosolic superoxide dismutase increase C. elegans lifespan? F. Cabreiro, R. Doonan, D. Ackerman, C. Araiz, D. Gems.
A Novel Regulator Linking Insulin/IGF-1 Signaling to Proteasome Activity. O. Matilainen, L. Arpalahti, C. I. Holmberg.
Quorum sensing in Caenorhabditis starvation. Alex Artyukhin, Leon Avery.
Uncovering the mechanisms for the antioxidant-like properties of divalent manganese in Caenorhabditis elegans. Cynthia Bach, Chandra Srinivasan.
Defining healthspan in Caenorhabditis elegans. Ankita Bansal, Kelvin Yen, Heidi A. Tissenbaum.
The impact of longevity controlling genes and stress-inducing environmental factors in the functionality of the ASH chemosensory neuron in aging worms. Daphne Bazopoulou, Trushal V. Chokshi, Nikos Chronis.
Functional studies of Homedomain-Interacting Protein Kinase using C. elegans as a model. S. Berber, E. Llamosas, H. R. Nicholas.
Regulation of the Xenobiotic Stress Response - Combinatorial Action of Nuclear Receptors? Leah Blackwell, Amanda Marra, Tim Lindblom.
Screening of EPAs ToxCast libraries using a C. elegans growth assay. Windy A. Boyd, Majro V. Smith, Julie R. Rice, Jonathan H. Freedman.
The herbal tonic icariin and its metabolites extend C. elegans healthspan via the insulin/IGF-1 pathway. Wai Jiao Cai, Pankaj Kapahi, Xin Min Zhang, Zi Yin Shen.
Young Caenorhabditis elegans Battling Stress: the Role of Ethanol and Enhanced Fat Storage in L1 Lifespan Extension. Paola Castro, Shilpi Khare, Steven Clarke.
The role of the homeodomain protein CEH-23 in longevity of mitochondrial ETC mutants in Caenorhabditis elegans. H. W. Chang, S. S. Lee.
The Checkpoint Protein PCH-2 Regulates Oocyte Quality in C. elegans . Chen-Shan Chen, Ronald Ellis.
Deletion of the ribosomal S6 kinase in daf-2 mutants synergistically extends C. elegans lifespan. Di Chen, Ben Goldstein, Alan Hubbard, Simon Melov, Pankaj Kapahi.
Insulin-like Signaling in Nutritional Control of L1 Development in C. elegans . Yutao Chen, Nicole Kurhanewicz, Ryan Baugh.
A nucleolar protein regulates xenobiotic detoxification genes via skn-1. Keith P. Choe, Hyacinth Empinado, Andrew Deonarine, Chi Leung.
Characterization of TMEM16 Ca2+-activated Cl- channels in C. elegans. Tashrique Alam, Katherine Hill-Harfe, Chi Leung, Ying Wang, Brian Harfe, Keith Choe.
Toxicity of silver nanoparticles via pmk-1 dependant GST and HIF-1 activation in Caenohabditis elegans. Jinhee Choi, DongYoung Lim, Jiyeon Roh, Hyunjeong Eom.
Functional toxicogenomic analysis of multi-wall carbon nanotube in Caenohabditis elegans. Jinhee Choi, Ji-Yeon Roh, Maribel Bruno, Yue Ge.
Role of endocytosis and ER proteostasis in C. elegans longevity. Ritika Das, Sneha Rath, Nam Lee, Lindsay Stolzenburg, Andrew V. Samuelson.
Protein aggregation as an inherent part of aging. D. David, N. Ollikainen, J. Trinidad, M. Cary, A. Burlingame, C. Kenyon.
A model to study drug-induced mitochondrial dysfunction. Richard de Boer, Stanley Brul, Hans van der Spek.
Targeting DNA Repair to Enhance Radiosensitivity in Notch-driven Tumor Stem Cells. X. Deng, D. Rothenstein, D. Michaelson, SN. Powell, Z. Fuks, EJ Hubbard, RN. Kolesnick.
Distinct DAF-12 activities influence C. elegans lifespan. Kathleen Dumas, Chunfang Guo, Hung-Jen Shih, Patrick Hu.
Cyclophilin D Modulation of Longevity and Mitochondrial Physiology. Julie C. Etzler, Deborah Holstein, James D. Lechleiter.
Steroid Signaling Mediates Longevity Responses to Dietary Restriction in C. elegans. Mindy Farris, Victor Pineda, Dhaval Patel, Weiqing Li.
Identification of a Novel Role for Tyrosine Aminotransferase in Insulin Signaling. Annabel Ferguson, Yongsoon Kim, Kaitlyn Kormanik, Patrick Hu, Alfred Fisher.
Engineering longevity in C. elegans. Ari E. Friedland.
Characterization of the neuromedin U receptor (NMUR) family and its role in the development and lifespan of C. elegans. Roxani Gatsi, Bakhtiyor Adilov, Wolfgang Maier, Martin Regenass, Joy Alcedo.
Investigating the Dynamic Role of Autophagy in C. elegans Subjected to Dietary Restriction. S. Gelino, M. Hansen.
Investigating the Effect of Anoxia Exposure on Lifespan and the Role of Age in Anoxia Tolerance in C. elegans. Jo M. Goy, Mary L. Ladage, Pamela A. Padilla.
A Genetic Regulatory Network that Controls the Heat Shock Response in C. elegans. Eric Guisbert, Daniel Czyz, Klaus Richter, Patrick McMullen, Richard Morimoto.
MTL-1, MTL-2 and CDR-1 are not essential in C. elegans resistance to cadmium. Kathryn L. Haas, Julie Hall, Jonathan Freedman.
Identification of a pathway involved in the cadmium-responsive transcriptional regulation of metallothionein expression. Julie Hall, Jonathan Freedman.
Osmotic stress and loss of Notch ligands extend C. elegans lifespan via FOXO and sirtuins. Edward N. Anderson, Mark Corkins, David Sinclair, Anne C. Hart.
EMS Mutagenesis of Early Embryos: Does checkpoint status affect the mutational spectrum? James Barry, Whitney Finstad, Numan Khan, Dean Williams, Phil Hartman.
The KGB-1 JNK signaling pathway negatively regulates FOS-1 transcription factor in stress response. Ayuna Hattori, Tomoaki Mizuno, Naoki Hisamoto, Kunihiro Matsumoto.
A Biochemical Approach for the Identification of new DAF-16 Binding-partners. Thomas W. Heimbucher, Fonslow Bryan, Yates Jonathan, Dillin Andrew.
DAF-12 regulates a connected network of genes to ensure robust developmental decisions. Daniel Hochbaum, Alfred L. Fisher.
The sexual dimorphic response to dietary restriction. Sakiko Honjoh, Yukiko Kajiwara, Eisuke Nishida.
C. elegans vang-1 modulates life span and stress resistance via insulin/IGF-1-like signaling. S. Honnen, C. Büchter, V. Schröder, A. Kampkötter, O. Bossinger.
Investigating the role of C. elegans BRAP-2 in regulation of the oxygen radical detoxification response. Queenie Hu, Janet Koon, Terry J. Kubiseski.
High throughput toxicity screen using C. elegans and propidium iodide. Piper R. Hunt, Nicholas Olejnik, Robert L. Sprando.
CeleST, a sophisticated software package for the simultaneous quantiation of multiple swimming C. elegans for aging and locomotion analysis. C. Ibanez-Ventoso, C. Restiff, S. Guo, D. Metaxas, M. Driscoll.
Intermittent fasting-induced longevity requires cholesterol in C. elegans. Akiko Ihara, Sakiko Honjoh, Masaharu Uno, Hiroyuki Yoshimura, Eisuke Nishida.
Genes involved in mevalonate and ubiquione metabolism are essential for delayed muscle aging. Luv Kashyap, Alfred Fisher.
Characterization of C. elegans mutants deficient in base excision repair genes. Yuichi Kato, Takahito Moriwaki, Atsumi Ikemoto, Kazunari Hashiguchi, Qiu-Mei Zhang-Akiyama.
Telomere lengthening in suppressor mutants of telomerase deficient Caenorhabditis elegans. Chuna Kim, Beomseok Seo, Junho Lee.
Caenorhabditis elegans HIM-6 has a 3-5 helicase activity and is responsible for DNA damage processing. Eunsun Kim, Moonjung Hyun, Sojin Park, Hyejin Park, Byungchan Ahn.
Delimiting a polymorphic longevity locus on the left arm of Chromosome IV using traditional and high throughput longevity assays. Gunnar Kleemann, Joshua Boom, Leonid Kruglyak, Coleen Murphy.
Identification of mutations that delay reproductive or somatic aging of Caenorhabditis elegans. Sandeep Kumar, Stacie E. Hughes, Cheng Huang, Kerry Kornfeld.
Translational Control of Tumor Formation in C. elegans. Caroline Kumsta, Malene Hansen.
The ESRE stress-response network - analysis of an evolutionary conserved pathway. Aleksandra P. Kuzmanov, David S. Fay.
NAD+ Recycling, Sirtuins, and Stress: A Complex Relationship. Stephanie E. Lange, Wendy Hanna-Rose.
Nucleotide Excision Repair and its regulation in C. elegans development. Andrea E. Karambelas, Daniel Cupac, Özge Z. Aydin, Gert Jansen, Jan H. J. Hoeijmakers, Wim Vermeulen, Hannes Lans.
Autophagy links lipid metabolism to longevity in C. elegans. Louis Lapierre, Sara Gelino, Alicia Meléndez, Malene Hansen.
Identification of glucose-regulatory genes using a genome-wide RNAi screen. Dongyeop Lee, Dae-Eun Jeong, Seung-Jae Lee.
GTP binding protein Nog1 homologue regulates fat storage, development and lifespan. Ho-Hyun Lee, Ju-Yeon Lee, Jeong-Hoon Cho.
AMP-dependent protein kinase regulates nutrition dependent diapause in C. elegans. Inhwan Lee, Young-Jai You.
OASIS, an open-access and user-friendly online application for survival analysis. Jae-Seong Yang, Hyun-Jun Nam, Mihwa Seo, Seong Kyu Han, Yonghwan Choi, Hong Gil Nam, Seung-Jae Lee, Sanguk Kim.
Exploring the function of progeroid WRN gene homologues in C. elegans. Hayley Lees, Lynne Cox, Alison Woollard.
A dominant mutation in xrep-3 encoding the bZIP transcription factor SKN-1 abnormally induces GST expression in Caenorhabditis elegans. Koichi Hasegawa, Chi K. Leung, Keith P. Choe, Johji Miwa.
Homeostatic regulation of the WDR-23/ SKN-1 stress response. Chi K. Leung, Keith P. Choe.
Differential roles of thioredoxin reductases in C. elegans. Weixun Li, Jeong Hoon Cho, Jaya Bandyopadhyay, Sunkyung Lee, Joohong Ahnn.
The affect of chronic hypoxia on developmental trajectory, lifespan, and egg-laying behavior. B. Little.
Lifespan extension with protection against β-Amyloid toxicity with FDA approved drugs discovered in a two species screen. Alex Lublin, Harshil Patel, Isoda Fumiko, Nguyen Linda, Hajje Daher, Swartz Marc, Mobbs Charles.
A large scale small molecule screen identifies a group of structurally related compounds that extend the lifespan of C. elegans. Mark Lucanic, Ivan Yu, Dipa Bhaumk, Jill Graham, Aaron Miller, Robert Hughes, Gordon Lithgow.
High Saturated Fat Diet Disrupts Mitochondrial Function via Reactive Oxygen Species Pathways in C. elegans. Maya Magana, Stephanie Bryner, Lucinda Carnell, Carin Thomas.
The Nuclear Receptor NHR-8 Regulates Sterol Metabolism, Development, and Lifespan in C. elegans. Daniel Magner, Joshua Wollam, Dangling Li, Adam Antebi.
The transcriptional changes associated with food type-dependent lifespan effects. Wolfgang Maier, Roxani Gatsi, Martin Regenass, Joy Alcedo.
A transgenerational effect on lifespan. Frederick G. Mann, Stuart Kim.
INS-18, one of Caenorhabditis elegans insulin-like peptides, is required for the crosstalk of TGF-β signaling with insulin/IGF-I signaling. Y. Matsunaga, K. Gengyo-Ando, S. Mitani, T. Iwasaki, T. Kawano.
Exploring real-time in vivo redox biology in Caenorhabditis elegans . Patricia Back, Winnok De Vos, Filip Matthijssens, Bart Braeckman.
Identification of longevity targets in C. elegans translation mutants. Philip McQuary, Joyce Chu, Malene Hansen.
The role of autophagy in lifespan extension by resveratrol and spermidine. Evgenia Megalou, Nektarios Tavernarakis.
Adaptation to hydrogen sulfide modulates protein homeostasis. Emily Fawcett, Kate Stoll, Dana L. Miller.
The analysis of mismatch repair in C. elegans. Takahito Moriwaki, Yuichi Kato, Satoru Ishikawa, Kazunari Hashiguti, Qiu-Mei Zhang-Akiyama.
C. elegans HSF-1 is a dynamic nuclear protein whose activity is affected by sumoylation in response to proteotoxic stress. Elizabeth Morton, Todd Lamitina.
Unexpected antagonistic pleiotropy in the sod-4 extracellular supreoxide dismutase gene in C. elegans. S. Murakami, H. Murakami, A. Yeh, B. V. Nia, D. Lim.
Clarifying misconceptions about age-related memory impairment (AMI). S. Murakami.
Characterization of cellular functions of UFD-2 and UFD-3, C-terminal adaptors for CDC-48, in C. elegans. Yuki Murayama, Yohei Sasagawa, Teru Ogura, Kunitoshi Yamanaka.
Studies on Toxicity of Nano Iron Employing Model System Caenorhabditis elegans. Supinder Kaur, Shreesh Raj Sammi, Pooja Jadiya, Aamir Nazir.
Dietary Epigenetics and Neurodegenerative Diseases: Effect of Calorie Restriction on Dopaminergic Neurodegeneration in Caenorhabditis elegans. Pooja Jadiya, Shreesh Raj Sammi, Supinder Kaur, Aamir Nazir.
AMPK activation is protective in models of neuron dysfunction and death in Huntingtons disease. Rafael Vazquez-manrique, Karine Cambon, Nicolas Offner, Aurélie Darbois, Anne-marie Orfila, Nicole Déglon, Christian Neri.
Neuroprotection by Sirtuin sir-2.1 from Expanded Polyglutamines Requires β-catenin in C. elegans and the Age-at-Onset of Huntingtons Disease is Modified by the β-catenin Repressor GSK-3β. J. Alex Parker, Cendrine Tourette, Nicolas Offner, Rafael Vasquez-Manrique, Arnad Mukhopadhyay, Aurelie Darbois, Sophie Menet, Anne-Marie Orfila, Guillaume Dolbeau, Susanne Swenke, Patrick Maison, Michael Orth, Alexis Brice, Alexandra Durr, Anne-Catherine Bachoud-Levi, Heidi Tissenbaum, Christian Neri, European Huntington’s Disease Network.
Circadian rhythms in C. elegans. Maria Olmedo, Martha Merrow.
Why Make Fat?: The Impact of de novo Fatty Acid Synthesis on Reproduction and Longevity. Carissa Perez Olsen, Marc R. Van Gilst.
Insulin Signaling and Dietary Restriction Differentially Regulate Glucose Metabolism to Impact C. elegans Healthspan. Brian D. Onken, Monica Driscoll.
The FLH family of transcription factors is epistatic with the insulin/IGF-1 signaling pathway and modulates L1 diapause and stress resistance in C. elegans. Maria Ow, Victor Ambros.
Characterization of exceptional longevity pathways in C. elegans. Jennifer Paek, Stephanie Chan, Xiao Xiao, Jacqueline Lo, Sean P. Curran.
Aluminium Toxicity and Elemental Composition Changes in Caenorhabditis elegans. Kathryn E. Page, David W. Killilea, Keith N. White, Catherine R. McCrohan, Gordon J. Lithgow.
Genetic Analysis of Age-Dependent Defects of C. elegans Touch Receptor Neurons. C.-L. Pan, C.-Y. Peng, C.-H. Chen, Steven L. McIntire.
Detection of DNA Strand Breaks detection in Caenorhabditis elegans using Comet assay. Sojin Park, Moonjung Hyun, Eunsun Kim, Hyejin Park, Byungchan Ahn.
Insulin receptor signaling prolongs lifespan under high glucose conditions by restoring glyoxalase-1 activity. Michael Pfeiffer, Andreas Schlotterer, Youssef Ibrahim, Georgi Kukudov, Thomas Flemming, Angelika Bierhaus, Peter Nawroth, Michael Morcos.
Caenorhabditis elegans APN-1 plays a vital role in maintaining genome stability. Chadi Zakaria, Henok Kassahun, Xiaoming Yang, Jean-Claude Labbé, Hilde Nilsen, Dindial Ramotar.
Gerontometabolites Define A Unique Metabolic Signature In Long-Lived Mit Mutants. Jeffrey J. Butler, Shane L. Rea.
Lifespan extension via eIF4G inhibition is mediated by post-transcriptional remodeling of stress response gene expression in C. elegans. Aric N. Rogers, Di Chen, Gregg Czerwieniec, Gawain McColl, Krysta Felkey, Simon Melov, Bradford W. Gibson, Alan Hubbard, Gordon Lithgow, Pankaj Kapahi.
Investigating the spatial and temporal dynamics of protein oxidation in C. elegans. Catalina Romero, Javier Apfeld, Walter Fontana.
Epidermal Growth Factor Signaling Activates The Ubiquitin Proteasome System To Modulate C. elegans Lifespan. Gang Liu, Jason Rogers, Coleen Murphy, Christopher Rongo.
The R148.3 (OcaB) gene controls longevity and fat accumulation in the nematode C. elegans. Catherine Roy-Bellavance, Évelyne Rondeau, Stéphanie Miard, Frédéric Picard.
The effects of nickel toxicity upon survival, growth, and reproduction in nematodes. C. D. Douglas, J. M. Besser, C. G. Ingersoll, D. Rudel.
SKN-1-independent oxidative stress signaling from mitochondria to the nucleus. Eva D. Runkel, Shu Liu, Ralf Baumeister, Ekkehard Schulze.
Understanding the emergence of dynamic response of the reproductive system of Caenorhabditis elegans to chronic heat stress. Patrick D. McMullen, Erin Z. Aprison, Peter Winter, Luis A. Amaral, Richard I. Morimoto, Ilya Ruvinsky.
The recruitment of HSR-9 (53BP1) in response to double-strand DNA breaks requires methylation of histone H4 Lysine 20 in C. elegans. Jinsun Ryu, Sang Jo Kang, Hyeon-Sook Koo.
Deciphering HIF-1 regulatory networks: An interdisciplinary approach to diagnosing stress resistant phenotypes. Jenifer Saldanha, Archana Parashar, Qi Ye, Santosh Pandey, Jo Anne Powell-Coffman.
Insulin signaling pathway genes facilitating thermotolerance and protein homeostasis. Sara Farrell, Lindsay Stolzenburg, Jesse Llop, David Johnson, Andrew V. Samuelson.
Caenorhabditis elegans NDX-1has an 8-oxo-7, 8-dihydrodeoxyguanosine 5-diphosphate pyrophosphatase activity that contributes to prevent against oxidative stress. U. Sanada, Qiu-Mei Zhang-Akiyama.
Gene by environment interaction reveals proteostasis sub network for adult health and longevity. A. R. Sanchez, S. Takano, P. L. Larsen.
Variable Pathogenicity Determines Individual Lifespan in C. elegans. Adolfo Sanchez-Blanco, Stuart Kim.
MicroRNA Modulation of C. elegans aging. Mitalie Shah, Mehul Vora, Monica Driscoll.
Regulation of Autophagy by RNF-5, an E3 Ubiquitin Ligase. S. Sheffy Levin, L. Broday.
Monascus-fermented dioscorea enhances oxidative stress resistance via insulin signaling pathway. Yeu Ching Shi, Tzu-Ming Pan, Vivian Liao.
The C. elegans WRN-2 having the exonuclease domain of Werner syndrome protein is required for efficient cell cycle arrest in response to ionizing radiation. Hyo ju Shin, Se jin Lee, Hyeon-Sook Koo.
The DAF-2 somatic longevity pathway interfaces with PRG-1-mediated germ cell immortality. Matt A. Simon, Eric Miska, Shawn Ahmed.
Non-monotonic relationship between tissue levels of 4-hydroxynonenal (4-HNE) and lifespan in C. elegans. Kevin E. McElhanon, Kira C. Bennett, Ludwika Zimniak, Piotr Zimniak, Sharda P. Singh.
The role of ubiquitin-conjugating enzymes in polyglutamine protein aggregation. Gregory A. Skibinski, Lynn Boyd.
Modeling membrane protein misfolding in C. elegans. Liping He, Jennifer Skirkanich, Lorenza Moronetti, Todd Lamitina.
The Lifespan Machine comes of age: Time-dependent changes in the action of insulin signaling are revealed by high-resolution mortality data. Nicholas Stroustrup, Javier Apfeld, Walter Fontana.
Identification of DNA maintenance genes specifying the extended longevity of the Mit mutants. Alessandro Torgovnick, Alfonso Schiavi, Roberto Testi, Shane Rea, Natascia Ventura.
Studies towards understanding the function of the transcription factor DAF-16. Jennifer M. A. Tullet, Caroline Araiz, Eugene Schuster, David Gems.
The mechanisms underlying an age-dependent reversal in the protective capacities of the non-neuronal JNK-homolog KGB-1. Kwame Twumasi-Boateng, Tim Wang, Linda Tsai, Lianqun Wu, Michael Shapira.
A conserved JNK/AP-1 module is a key mediator of intermittent fasting-induced longevity in C. elegans. Masaharu Uno, Sakiko Honjoh, Eisuke Nishida.
A genome-wide RNAi screen identifies alternative pathways for activating phase 2 detoxification gene expression in response to arsenite. Helen M. Crook, Monika Oláhová, Elizabeth A. Veal.
Electron transport chain disruption extends lifespan and reduces fat accumulation through p53-dependent induction of autophagy. A. Schiavi, A. Torgovnick, E. V. Megalou, R. Testi, N. Tavernarakis, N. Ventura.
Reproductive Aging in C. elegans Males. I. Chatterjee, P. Vijay, C. Ibanez-Ventoso, J. Bair, M. Driscoll, A. Singson.
Investigating the function of NAD+ salvage biosynthesis in energy production and storage. Wenqing Wang, Kelsey J. Krebs, Marisa J. Pacella, Wendy Hanna-Rose.
The effects of altered omega-3 fatty acid composition on lifespan and stress. Joel Greggain, Christopher Webster, Jennifer Watts.
Regulation of oocyte quality by the level of germ cell death. Qing Wei, Sara Andux, Ronald Ellis.
Identifying natural genetic variation in stress and aging pathways in Caenorhabditis remanei populations. John H. Willis, Patrick Phillips.
A GATA transcriptional circuit guides aging in C. elegans. Xiao Xu, Stuart Kim.
Identification of molecular compensation system of sod-genes expression in nematode C. elegans. Koumei Yazaki, Sumino Yanase, Taro Sakamoto, Yasuhito Nakagawa, Naoaki Ishii.
A Mitochondrial Superoxide Signal Triggers Increased Longevity in C. elegans. Wen Yang, Siegfried Hekimi.
Nuclear Envelope Proteins: Regulation of Meiotic Recombination and Role in Reproductive Aging. Alice Y. Ye, Needhi Bhalla.
Dissecting the interaction between insulin/IGF-1 and TOR signaling pathways. Kelvin Yen, Heidi Tissenbaum.
Deciphering mechanisms by which EGF signaling protects against the aging process. Simon Yu, Hiroaki Iwasa, Jian Xue, Monica Driscoll.
The role of GATA transcription factors elt-5 and elt-6 in aging. Stephanie M. Zimmerman, Yelena V. Budovskaya, Stuart K. Kim.
Physiology: Dauer larvae and metabolism
Small molecule modulators of dauer signaling pathways and life span. Ben Becker, Adam Antebi.
CYP-35A5 and NHR-88 act together to coordinate brood size. Alison Brooks, Marc Van Gilst.
Role of G-protein coupled receptor signaling in C. elegans fat metabolism. Claudio Comunian, Tallie Noble, Supriya Srinivasan.
Do Dauers differ ? - Comparative analysis of Dauer proteome and metabolome signatures in three nematode species. Zisong Chang, Guido Mastrobuoni, Hans-Joachim Knölker, Stefan Kempa, Christoph Dieterich.
Functions of Acyl-CoA Binding Proteins in C. elegans. Ida C. Elle, Pernille K. Birck, Thuc T. Le, Nils J. Faergeman.
Defining the role of ABC transporters in vitamin B12 metabolism using the model organism Caenorhabditis elegans. Julie-Anne Fritz, Megan McDonald, Padmaja Dharwadkar, Deborah Scheuchner, Floyd Snyder, Avalyn Lewis, Liang Li, Roy Gravel.
Prostaglandin signaling in dauer formation and aging. Makoto Horikawa, Adam Antebi.
GPCR signaling in free-living and parasitic nematode models: the cholecystokinin story. T. Janssen, L. Peeters, I. Beets, L. Temmerman, E. Meelkop, N. Suetens, W. Grant, L. Schoofs.
ENPL-1/GRP94 interacts with ASNA-1 and promotes Insulin/IGF secretion in Caenorhabditis elegans. Balasubramanian Natarajan, Peter Naredi, Gautam Kao.
Data mining of global interactome studies yields new modulators of C.elegans insulin signaling. Ola Billing, Balasubramanian Natarajan, Ateequr Rahman Mohammed, Peter Naredi, Gautam Kao.
Neuronal secretion of C. elegans DAF-28/insulin requires functional mitochondria. Ola Billing, Peter Naredi, Gautam Kao.
HRG-9 regulates systemic heme homeostasis in C. elegans. T. Korolnek, I. Hamza.
Y47D7A.16: a riboflavin tranporter in C. elegans and homolog of human Riboflavin Transporter 2. Craig W. Lamunyon, Arundhati Biswas, Jason Rothman, Hamid Said.
DHS-21, a dicarbonyl/L-xylulose dehydrogenase (DCXR) ortholog, regulates longevity and reproduction in C. elegans. Son T. Le, Tae-Woo Choi, Gunasekaran Singaravelu, Sun-Kyung Lee, Joohong Ahnn.
Regulation of insulin and neuropeptide signaling by the Bardet-Biedl Syndrome complex. Brian H. Lee, Kaveh Ashrafi.
Dafadine Promotes Dauer-Formation and Lifespan-Extension of C. elegans by Inhibiting the Cytochrome P450 DAF-9. Genna M. Luciani, Lilia Magomedova, Rachel Puckrin, Malene L. Urbanus, Iain M. Wallace, Guri Giaever, Corey Nislow, Carolyn L. Cummins, Peter J. Roy.
Local triglyceride synthesis by DGAT-2 promotes lipid droplet expansion. Ningyi Xu, Shaobing Zhang, Ronald Cole, Sean McKinney, Fengli Guo, HoYi Mak.
Role of lipid signaling molecules in energy balance in C. elegans. Thomas P. Mathews, Tallie Noble, Benjamin F. Cravatt, Supriya Srinivasan.
Histidine Protects Against Zinc and Nickel Toxicity in C. elegans. John T. Murphy, Janelle J. Bruinsma, Daniel L. Schneider, Sara Collier, James Guthrie, Asif Chinwalla, J. David Robertson, Elaine R. Mardis, Kerry Kornfeld.
Starvation-signalling in gpb-2. Robert H. Pollok, Chanhee Kang, Leon Avery.
Knockout of the folate tranporter folt-1 induces sterility and metabolic defects that are alleviated by supplementation with other B vitamins. Jason A. Rothman, Craig LaMunyon.
The role of rsks-1 in regulation of fat metabolism. Ming Sheng, Josefin Nyström-Friberg, Staffan Lundstedt, Simon Tuck.
Determining the role of heterotrimeric G proteins in dauer entry. Julien Shoenfeld, Bryan Danzi, Edith Myers.
Glycogen debranching enzyme AGL-1 regulates embryogenesis and lifespan through AMP Kinase dependent and independent pathways. Jeffrey S. Simske.
S-adenosylmethionine synthetase SAMS-1 regulates brood size in C. elegans. Hiroko Tamiya, Keiko Hirota, Yuta Takahashi, Hiroaki Daitoku, Naoaki Ishii, Akiyoshi Fukamizu.
Genetic Regulation of Starvation Induced Adult Reproductive Diapause (ARD). Bargavi Thyagarajan, Giana Angelo, Marc Van Gilst.
Increasing C. elegans lifespan by inhibiting E. coli folate metabolism, but not E. coli proliferation. Bhupinder Virk, David Dixon, David Weinkove.
PNC-1 regulation NAD+ synthesis but not absolute NAD+ levels promotes muscle development and function in C. elegans. Tracy L. Vrablik, Wenqing Wang, Wendy Hanna-Rose.
Purification and characterization of C. elegans cytoplasmic malate dehydrogenase. Wei Gu, Penelope L. Lindsay, Justin W. Spengler, Katherine M. Walstrom.
Rationing of Energy Stores in C. elegans during Dauer Stage. Meng Xie, Richard Roy.
Suppressors of daf-18 L1 arrest phenotype and investigating a role for DAF-18 protein phosphatase activity. Michael R. Zanetti, Peter E. Hand, Ian D. Chin-Sang.
Indolequinazoline Alkaloids Evodiamine and Rutaecarpine Suppress Multivulva of an Activating Ras Mutant. Kosuke Amagasa, Kahori Asano, Yusuke Morioka, Asuka Kambe, Hideshi Inoue.
Role of FSHR-1 targets in regulating the Caenorhabditis elegans innate immune response. Hannah L. Anthony, Jonathan D. Hibshman, Jennifer R. Powell.
O-GlcNAc cycling is a regulator of innate immunity in Caenorhabditis elegans. Michelle R. Bond, Michael W. Krause, John A. Hanover.
Comparative Metabolite Profiling Identifies Toxic Phenazines Produced by Pseudomonas aeruginosa. Brent Cezairliyan, Nawaporn Vinayavekhin, Daniel Grenfell-Lee, Grace Yuen, Alan Saghatelian, Frederick Ausubel.
Characterization of the pathogenicity of Enterohaemorrhagic E. coli in C. elegans. Ting-Chen Chou, Cheng-Ju Kuo, Hao-Chieh Chiu, Ching-Ming Wu, Chang-Shi Chen.
SIR-2.3 is involved in Cry5B pore-forming toxin defense in C. elegans. Huan-Da Chen, Cheng-Yuan Kao, Raffi V. Aroian, Chang-Shi Chen.
Characterization of the Intestinal Autophagy Response Against Vibrio cholerae hemolysin. Hediye N. Cinar, Surasri N. Sahu, Oluwakemi Odusami.
Testing the "glycine zipper" model for the formation of toxic β-amyloid oligomers. Vishantie Dostal, Gin Fonte, Christine M. Roberts, Patrick Gonzales, Christopher D. Linlk.
Characterization of Viruses that infect Caenorhabditis Nematodes. Carl J. Franz, Yanfang Jiang, Guang Wu, Tony Belicard, Marie-Anne Felix, David Wang.
Muscle degeneration: a protein misfolding problem? April R. Reedy, Angela Rea-Boutrios, Maité Carre-Pierrat, Laurent Segalat, Kathrin Gieseler.
Mitochondrial Fission Protects C. elegans from Amyloid-Beta Toxicity. Patrick K. Gonzales, Christopher D. Link.
Molecular characterization and suppression of srf-2, a DUF23 surface-antigenicity gene that affects bacterial infection. Maria J. Gravato-Nobre, Simon Spiro, Tom Baker, Dave Stroud, Jonathan Hodgkin.
Host seeking and the evolution of olfactory behavior in parasitic nematodes. Elissa A. Hallem, Adler R. Dillman, Manon L. Guillermin, Paul W. Sternberg.
Manganese-transporters have an important roles in innate immune system in Caenorhabditis elegans. Hwan-Jin Kim, Ju-Yeon Lee, Joeng-Hoon Cho.
A novel, high-throughput, liquid killing assay of P. aeruginosa infection of C. elegans provides insight about pathogenesis and host defense. Natalia V. Kirienko, Jonah Larkins-Ford, Carolina Wählby, Frederick M. Ausubel.
Screening of natural products as anti-infectives towards Staphylococcus aureus using an in vivo Caenorhabditis elegans infection model. Cin Kong, Man-Wah Tan, Sheila Nathan.
Genetic analysis of Caenorhabditis elegans responses to grassland soil bacteria reveals both specific and general functions. Vinod Kurumathurmadam Mony, Michael Herman.
Identifying host factors required for Sindbis virus replication using C. elegans. Michael Laha, Hugo Decker, Ellen Bradley, Charles Rice, Margaret MacDonald, Shai Shaham.
Innate immune response to microsporidian infection. Amy T. Ma, Emily R. Troemel.
Identifying P. aeruginosa factors that activate C. elegans immunity. Deborah L. McEwan, Frederick M. Ausubel.
Protective role of dnj-27, a thioredoxin family member, on C. elegans models of Alzheimer's and Parkinson's Diseases. F. Munoz-Lobato, CD Link, S. Hamamichi, KA Caldwell, GA Caldwell, A. Miranda-Vizuete.
Genetic architecture of natural variation in Caenorhabditis elegans pathogen avoidance. R. Nakad, B. Snoek, S. Ellendt, T. G. Mohr, K. Dierking, J. E. Kammenga, H. Schulenburg.
Morphological Study of Muscle Degeneration in C.elegans. Nicolas Brouilly, Claire Lecroisey, Laura Pierson, Kathrin Gieseler.
Mutations in bus-10, encoding a putative membrane protein, alter both susceptibility and resistance to different bacterial infections. Delia M. O'Rourke, Rebecca Price, Nicholas Lillios, Maria Gravato-Nobre, Jonathan Hodgkin.
Regulation of PMK-1 p38 MAPK-dependent immunity by the transcription factor ATF-7 in C. elegans. Daniel J. Pagano, Dennis H. Kim.
Genomic Analysis of Immune Response Against Vibrio cholerae Hemolysin in Caenorhabditis elegans . Surasri Sahu, Jada Lewis, Isha Patel, Serdar Bozdag, Joseph LeClerc, Hediye Cinar.
A Feeding RNAi Screen to identify novel genes in anti-viral immunity in C. elegans. Shruthi Satish, Zhihuan Gao, Stephanie Coffman, YuanYuan Guo, Michael Cantrell, Gina Broitman-Maduro, Morris Maduro, Shou-wei Ding.
Characterization of pathogenesis of S. aureus and involvement of checkpoint response in C. elegans. Lone V. Scholer, Steffen Noerregaard, Frederik D. Hansen, Kurt Fuursted, Anders Olsen.
Towards a SNP map for Heterorhabditis bacteriophora. Hillel Schwartz, Paul Sternberg.
LIN-7 PDZ Modulates DAF-2-mediated Innate Immunity Signaling and Infection Sensitivity in Caenorhabditis elegans. Xiao-Hui Sem, Jason Kreisberg, Mikael Rhen, Patrick Tan.
Key residues of Cry5B structure and function: mutagenesis by alanine screening. Jillian Sesar, Yan Hu, Raffi V. Aroian.
Caenorhabidits elegans commensals provide protection from P. aeruginosa infection. Sirena Montalvo-Katz, Oliver Huang, Susannah Tringe, Michael Shapira.
Fat Burning in Sleeping Worms: Regulation of Multiple Signaling Pathways by Kruppel Like Factors. Shahid S. Siddiqui, Sarwar Hashmi, Jun Zhang, Chen Yang, Immanuel Dhansingh, David Gozal.
Microarray analysis of pathogen response in C. elegans and P. pacificus reveals differences in molecular effectors of innate immunity. Amit Sinha, Igor Iatsenko, Robbie Rae, Ralf J. Sommer.
Expression patterns of an FSHR-1 transcriptional target gene upon infection of C. elegans by P. aeruginosa. Jordann A. Smak, Jennifer R. Powell.
Responses of C. elegans to Pathogenic Challenge. Gregory Stupp, Steven L. Robinette, Ramadan Ajredini, Paul A. Gulig, Arthur S. Edison.
Molecular characterization of Coprinopsis cinerea lectins-mediated toxicity against C. elegans. Katrin Stutz, Alex Butschi, Silvia Bleuler-Martinez, Mario Schubert, Markus Aebi, Markus Künzler, Michael O. Hengartner.
A C. elegans model for cell autonomous, non-autonomous, and delayed hypoxic injury. Chun-Ling Sun, C. Michael Crowder.
G-protein coupled receptor OCTR-1 controls innate immunity by regulating non-canonical unfolded protein response genes. Jingru Sun, Varsha Singh, Rie Kajino-Sakamoto, Alejandro Aballay.
A Calpain based muscle repair/remodelling system in C. elegans. Beth Oczypok, Tim Etheridge, Brandon Fields, Lew Jacobson, Nate Szewczyk.
Understanding the effects of the intracellular pathogen Nematocida parisii infection of the C. elegans intestine on intracellular trafficking and cytoskeleton components. Suzy Szumowski, Emily Troemel.
C. elegans clhm-1 encodes a novel voltage-gated, Ca2+ permeable ion channel that regulates cell excitability. Jessica E. Tanis, Zhongming Ma, Predrag Krajacic, Liping He, J. Kevin Foskett, Todd Lamitina.
Non-lytic, actin-based exit of intracellular parasites from C. elegans intestinal cells. Kathleen A. Estes, Emily R. Troemel.
Development of C. elegans models for Amyotrophic Lateral Sclerosis. Alexandra Vaccaro, Arnaud Tauffenberger, Alex Parker.
The interaction between C. elegans and the emerging nosocomial pathogen Stenotrophomonas maltophilia. Corin White, Vinod Mony, Brian Darby, Michael Herman.
Enterococcus infection of Caenorhabditis elegans as a model of innate immunity. Grace J. Yuen, Read Pukkila-Worley, Frederick M. Ausubel.
Dissecting the molecular pathway underlying IFT modeling. Qing Zhang, Yuxia Zhang, Qing Wei, Jinghua Hu.
Neurobiology: Neuronal development
The Role of the Argonaute Protein, ALG-1, in C. elegans Neural Development. Cristina Aguirre-Chen, Christopher M. Hammell.
The atypical Cdc-42-like GTPases CHW-1 and CRP-1 redundantly regulate axon pathfinding and cell migration. Jamie K. Alan, Erik A. Lundquist.
Dissections of lin-11 neuronal enhancers in C. elegans and C. briggsae. Siavash Amon, Bhagwati Gupta.
Rapid and reversible arborization of IL2 neurons during dauer development. Nathan E. Schroeder, Rebecca J. Androwski, Maureen M. Barr.
To branch or not to branch? Role of png-1 in limiting axon branching in C.elegans. Nasrin Babadi, Claudia Arauz, Anna Su, Antonio Colavita.
Cholinergic motor neurons are required for the positioning of GABA receptor clusters at the neuromuscular junction. Belinda Barbagallo, Michael Francis.
An Investigation into the Affect of Neuronal Activity on Proper Neural Connectivity in C. elegans. Ben Barsi-Rhyne, Kristine Miller, Joori Park, Emma Holdrich, Miri VanHoven.
Investigation of the UNC-6/Netrin and UNC-40/DCC-Mediated Synaptic Partner Recognition Pathway in C. elegans. Kelli L. Benedetti, Aruna Varshney, Akshi Goyal, Dianicha Santana-Nuńez, Pooja Prasad, Joori Park, Miri VanHoven.
A Family of Eight Small 2-Ig Domain Proteins Functions to Protect Neuronal Architecture. Cassandra Blanchette, Claire Bénard.
A prkl-1suppressor screen to identify new planar cell polarity components involved in neuronal polarity. D. Carr, J. Visanuvimol, L. Sanchez-Alvarez, A. Colavita.
Loss of the soluble guanylate kinase guk-1 results in multiple developmental defects. Margaret R. Casazza, Douglas Portman.
Integrin Cooperates with UNC-40 to Guide Muscle Arm Extension. Kevin K. Chan, Peter J. Roy.
UNC-119 acts to maintain neuronal differentiation. Brittney Chilton, Andrew Gorzalski, Fern Bosada, Scott Clark.
An F-box protein FSN-1 Regulates Retrograde Insulin Signalling. Wesley Hung, Christine Hwang, Edward Liao, Jyothsna Chitturi, Ying Wang, Hang Li, Mei Zhen.
Sex pheromone perception in C. elegans is under the regulation of TGFβ and IGF signals acting in the nervous system. KC Fan, KL Chow.
DAF-18/PTEN regulates neurodevelopmental axon outgrowth through isoform-specific DAF-16/FOXO activity. R. Christensen, A. Byrne, M. Hammarlund, D. A. Colón-Ramos.
A screen for mutants with defective hypodermal attachment of mechanosensory neurons. Brian Coblitz, Martin Chalfie.
Mechanisms of BAG sensory cilia specification. Astrid Cornils, Piali Sengupta.
The LAMMER kinase MADD-3 Functions Cell-Autonomously to Direct Muscle Arm Extension. Serena A. D'Souza, Louis Barbier, Rachel Puckrin, Peter Roy.
Regulation of axon extension and termination by RPM-1. Maria Fernanda daSilva, Scott Clark.
Identification of novel loci interacting with the Kallmann Syndrome gene kal-1. Carlos A. Diaz-Balzac, Nathali Gomez, Hannes Buelow.
Syndecan modulates growth cone migration and morphology during axon regeneration. Tyson Edwards, Marc Hammarlund.
COEL-1, a metazoan specific protein, is required for proper function of microtubules in Touch Receptor Neurons. M. Y. Frederic, V. F. Lundin, M. D. Whiteside, D. K. Tu, D. L. Baillie, J.-M. Bellanger, H. Hutter, F. S. Brinkman, M. R. Leroux.
Characterization of intracellular calcium signaling within damage C. elegans neurons . Lin Sun, Samuel Chung, Fay Gao, Kevin Roodhouse, Christopher V. Gabel.
An EMS screen in C. elegans for genes affecting RID axon guidance. Q. Ge, X. Li, X. Huang.
Development and Function of RIS, a Caenorhabditis elegans GABAergic interneuron. Marie Gendrel, Diana Cai, George Baison, Darym Alden, Oliver Hobert.
Mechanisms of UNC-86-mediated gene regulation in the BDU neurons. Patricia Gordon, Oliver Hobert.
EGL-13, a SOX transcription factor, regulates neuronal cell fate determination of the BAG neurons. Jakob Gramstrup Petersen, Roger Pocock.
RAE-1 a novel PHR binding protein regulates axon termination and synapse formation. B. Grill, L. Chen, E. D. Tulgren, S. T. Baker, M. Anderson, W. Bienvenut, Y. Jin, C. C. Garner.
The role of Eph signaling in amphid commissure guidance. Emily N. Grossman, Andrew D. Chisholm.
Axon guidance defects displayed by zfp-1 and lin-35 mutants depend on the presence of the transgene oxIs12. Stephan Gysi, Michael Hengartner.
A new class of mutants alters dendrite length in URX oxygen-sensing neurons. Ian G. McLachlan, Valeri J. Thomson, Shai Shaham, Maxwell G. Heiman.
Wnt signals and Frizzled receptors regulate dendrite formation in C. elegans . Leonie Kirszenblat, Divya Pattabiraman, Brent Neumann, Massimo A. Hilliard.
Regulation of expression of the Netrin axon guidance system. Kelly L. Howell, Oliver Hobert.
The C. elegans CDK8 Mediator module regulates specific axon guidance decisions in the ventral cord and suppresses SAX-3/ROBO activity during dorsal axon navigation. Andreas Steimel, Jinkyo Suh, Angela Hussainkhel, Samineh Deheshi, Jennifer Grants, Richard Zapf, Donald Moerman, Stefan Taubert, Harald Hutter.
New methods to study nerve bundle organization. Richard Ikegami, Gian Garriga.
Searching for factors required for BAG cell fate determination. Vaida Juozaityte, Roger Pocock.
Sexual specification of ventral cord neurons. Andrea K. Kalis, Djem Kissiov, Breanna Tetreault, Jennifer Ross Wolff.
Roles of 2-Ig domain proteins ZIG-1, ZIG-5, ZIG-8 and their interactions with SAX-7 in neuronal maintenance. Anagha Kulkarni, Claire Bénard.
Cell fate determination of oxygen sensing neurons in C. elegans. Kasper Langebeck-Jensen, Teresa Rojo, Roger Pocock.
Genome-wide RNAi screening for vhp-1 suppressors in C. elegans. Chun Li, Naoki Hisamoto, Paola Nix, Shuka Kanao, Tomoaki Mizuno, Michael Bastiani, Kunihiro Matsumoto.
Neuron developmental defects caused by ethanol exposure. Conny H. C. Lin, Sasha Sa, Ken Ke-Chih Huang, Catharine Rankin.
DM-domain genes dmd-3 and mab-23 specify critical cell fate characteristics in the male C. elegans ray sensorimotor circuit. M. Siehr, A. Sherlekar, P. Koo, X. Bian, D. Portman, R. Lints.
Sensory Nerve Ending Regeneration during Development of the C. elegans Dopaminergic PDE Neurons. Xuemin Lu, Tori Hatch, Rita Droste, Robert Horvitz.
Identifying Genes that turn Skin Cells into Neurons. G. Minevich, M. Doitsidou, S. Gowtham, H. Korswagen, O. Hobert.
UNC-40 is required for neuronal morphogenesis and synapse distribution in the serotonergic NSM neuron in C. elegans. Jessica C. Nelson, Daniel Colón-Ramos.
C. elegans as model system to study Nephrin/Neph protein functions. Nicola Wanner, Tobias B. Huber, Elke Neumann-Haefelin.
UNC-73/Trio, the Rac GTPases, UNC-33/CRMP and UNC-44/Ankyrin are required for limiting the extent of growth cone filopodia protrusion and ectopic axon branching. Adam Norris, Erik Lundquist.
A copine like protein CPNA-2 regulates neural localization of UNC-6/Netrin in Caenorhabditis elegans. Taro Asakura, Kumiko Fujita, Yoshio Goshima, Ken-ichi Ogura.
Wnt, Frizzled, CAM-1/ROR and LIN-18/RYK signaling establish anteroposterior neuronal polarity. Daniel Oliver, Scott Clark.
microRNA regulation of neuronal guidance in C. elegans. Mikael Egebjerg Pedersen, Goda Snieckute, Roger Pocock.
A Forward Genetic Screen to Identify New Synaptic Partner Recognition Genes. Shanté O'Hanlon, Anabel Ortiz, Minh Pham, Mekala Raman, Miri VanHoven.
CEH-28 regulates neuroendocrine function of the M4 pharyngeal neuron by activating dbl-1 expression. Kalpana Ramakrishnan, Paramita Ray, Peter Okkema.
HLH-3 expression is necessary during embryogenesis for proper HSN differentiation and function. Saleel V. Raut, Aixa Alfonso.
A genetic analysis of the axon guidance of the C. elegans pharyngeal neuron M1. Osama M. Refai, Evvi Rollins, Patricia Rohs, Jeb Gaudet.
PLR-1 regulates Wnt signaling by reducing cell surface levels of Frizzled and CAM-1/ROR. Ryan Robinson, Scott Clark.
MIG-10/Lamellipodin and Abelson-interactor-1(ABI-1) act together to mediate directed migration and outgrowth in C. elegans. M. McShea, S. Zhang, M. Kuhlwein, S. Hashmi, M. Dubuke, C. Grant, K. L. Schmidt, E. G. Stringham, E. F. Ryder.
MADD-2 Regulates Guidance to the Midline through an UNC-40/DCC pathway in C. elegans. Ashwin Seetharaman, Mariam Alexander, Guillermo Selman, Peter Roy.
The glutamatergic nervous system of C.elegans. E. Serrano, O. Hobert.
Doublets well kept secret: the sister singlets. Malan Silva, Robert O’Hagan, Ken Nguyen, David H. Hall, Maureen Barr.
Netrin instructs presynaptic assembly through a synaptic MIG-10 isoform and the actin cytoskeleton. Andrea K. Stavoe, Jessica C. Nelson, Daniel A. Colón-Ramos.
Regulatory logic of pan-neuronal gene expression in C. elegans. Nikolaos Stefanakis, Inés Carrera, Oliver Hobert.
The Arp2/3 complex and UNC-115/abLIM act downstream of CDC-42 in neuronal lamellipodia and filopodia formation. Eric C. Struckhoff, Erik A. Lundquist.
UNC-40/DCC, PTP-3/LAR, and MIG-21 regulate anterior-posterior polarization and migration of the Q neuroblasts. Lakshmi Sundararajan, Erik Lundquist.
The Role of 3-O Sulfation of Heparan Sulfate in Neuronal Development in C. elegans. Eillen Tecle, Hannes Buelow.
HBL-1 patterns synaptic remodeling in C. elegans. Katherine L. Thompson-Peer, Jihong Bai, Joshua Kaplan.
The Messiness of Combinatorial Control. Irini Topalidou, Martin Chalfie.
The prolyl 4-hydroxylase dpy-18 is required for specific axon guidance events. Nanna Torpe, Roger Pocock.
PPM-1, a PP2Cα/β phosphatase, regulates axon termination and synapse formation in C. elegans. E. Tulgren, S. Baker, L. Rapp, A. Gurney, B. Grill.
Sox genes in early nervous system development. Berta Vidal Iglesias, Oliver Hobert.
Identifying new players involved in dorsal-ventral axon guidance in C.elegans. Jinbo Wang, Xia Li, Mei Zhen, Xun Huang.
Ciliogenesis in Caenorhabditis elegans requires genetic interactions between nphp-2 and transition zone associated genes. Simon RF Warburton-Pitt, Andrew R. Juaregui, Chunmei Li, Michel R. Leroux, Maureen M. Barr.
Understanding the molecular mechanisms that mediate axon outgrowth termination in C. elegans. William Wung, Johann Zaroli, Kelli Benedetti, Phil Knezevich, Joori Park, Nathan Cook, Miri VanHoven.
The RFX Transcription Factor DAF-19 Couples Toll-interleukin 1 Receptor Domain Protein TIR-1 Signaling to Regulation of Neuronal Activities in C. elegans. Y. Xie, M. Moussaif, S. Choi, J. Sze.
Tectonic contributes to transition zone complexes required for proper ciliogenesis. Laura Yee, Rachel Bowie, Oliver Blacque, Kaveh Ashrafi, Jeremy Reiter.
Characterization of a L1 axon guidance phenotype in the mechanosensory neurons and the role of lethal genes in axon guidance. Fabian P. S. Yu, Ahmed M. Mohamed, Ian D. Chin-Sang.
Searching for Negative Regulators of Neurite Outgrowth in Caenorhabditis elegans. Bo Zhang, Song Song, Xun Huang, Mei Ding.
The C2H2 Zn finger transcription factor LSY-27 is involved in controlling a lateralized neuronal differentiation program in C.elegans. Feifan Zhang, Maggie O’Meara, Oliver Hobert.
Identification of the sex pheromone receptors in AWA neuron. Yuan Zhou, King-Lau Chow.
Neurobiology: Synaptic function and circuits
Interaction of an alpha-catulin homologue, CTN-1, with dystrobrevin (DYB-1) determines the localization of BK channels in Caenorhabditis elegans muscles. Linu S. Abraham, Hyun J. Oh, Hongkyun Kim.
Sink or Swim: A Screen for Dopamine-Dependent Modulation of Swimming Behavior. Sarah R. Baas, J. Andrew Hardaway, Shannon L. Hardie, Sarah Whitaker, Bing Zhang, Randy D. Blakely.
The Stomatins UNC-1 and STO-6 Function in the C. elegans Motor Circuit. Louis Barbier, Michelle Po, Taizo Kawano, Mei Zhen.
Degeneracy and neuromodulation in the thermosensory circuit regulates robustness in thermosensory behaviors in C. elegans. Matthew Beverly, Sriram Anbil, Harold Bell, Piali Sengupta.
Genetic and Neural Pathways Underlying Light-induced Inhibition of Pharyngeal Pumping by C. elegans. Nikhil Bhatla, Bob Horvitz.
Genetic, pharmacological and calcium imaging analysis of mutants affecting HSN activity. Robyn Branicky, William R. Schafer.
The receptor tyrosine phosphatase clr-1 is required for axon regeneration in C. elegans. Rebecca Brown, Marc Hammarlund, Stephen Strittmatter.
A screen for suppressors of RHO-1 neuronal signaling identifies the dopamine reuptake transporter DAT-1. Kimberley Bryon, Andrew Porter, Rachel McMullan, Stephen Nurrish.
Comparative connectomics reveals the neurobiological basis for predatory feeding behavior in Pristionchus pacificus. Daniel J. Bumbarger, Metta Riebesell, Ralf J. Sommer.
Dopamine-mediated effects of phenylethylamine in living worms and isolated embryonic neurons. Bryan Safratowich, Rochelle Wickramasekara, Lucia Carvelli.
CALM-1 is a Calcium Dependent Regulator of Synaptic Adhesion During Neuronal Development. Raymond Caylor, Brian Ackley.
Muscarinic signaling in motor neurons facilitates neurotransmission and is dependent on Ca++ and sphingosine kinase, sphk-1. Jason P. Chan, Derek S. Sieburth.
How larvae wiggle: functional analysis of the L1 larva locomotory circuit. Sway P. Chen, Anji Tang, Quan Wen, Aravinthan D. T. Samuel.
Sensory inputs regulate excitatory synaptic transmission at neuromuscular junctions. S. Choi, Z. Hu, J. M. Kaplan.
C. elegans: A Neurological Model to Characterize a Small Conductance Calcium-Activated K+ Channel. CK Chotoo, DC Devor, CJ Luke.
A computational model of associative learning and chemotaxis in the nematode worm C. elegans. Netta Cohen, Peter Appleby.
The C. elegans ERG (Ether-a-Go-Go Related Gene) K+ channel is a synaptically localized inhibitor of vulval muscle electrical excitability. Kevin M. Collins, Michael R. Koelle.
Synaptic Change During C. Elegans Lethargus. Nooreen S. Dabbish, David M. Raizen.
Monoamine Oxidase Inhibitors in Monoamine Receptor Mutants. Janet Duerr, Nanda Filkin, Kiel Kreuzer, Joseph Ipacs, Theresa White.
The Role of Palmitoylation in Neuronal Exocytosis in Caenorhabditis elegans. Matthew Edmonds, Timothy Frost, Mary Doherty, Alan Morgan.
Suppressors of neuronal RHO-1 reveal multiple downstream pathways. Muna Elmi, Andrew Porter, Rachel McMullan, Stephen Nurrish.
Circuits for Copulation in the C. elegans Male Tail. A. Bloniarz, T. Jarrell, Y. Wang, M. Xu, D. H. H. Hall, S. W. Emmons.
Function of VAV-1 in nervous system control of locomotion. Amanda Fry, Kenneth Norman.
The functional connectivity of male-specific CEM neurons in C. elegans. Lan Fu, King L. Chow.
Dopamine signaling for regulating experience-dependent odor avoidance. Kosuke Fujita, Kotaro Kimura.
A Co-operative Regulation of Neuronal Excitability by UNC-7 Innexin and NCA/NALCN Leak Channel. Magali Bouhours, Michelle Po, Shangbang Gao, Lin Xie, Wesley Hung, Hang Li, John Georgiou, John Roder, Mei Zhen.
Analysis of the Molecular Mechanism of Serotonin Signaling in C. elegans. Guliz Gurel, Michael Koelle.
Identification of chloride transporters that regulate GABA signaling. B. Han, A. Bellemer, M. Koelle.
Partners in Fatty Acid Beta Oxidation: Role of KLF-3 in Fat Burning and Reproductive Behavior of C. elegans. Sarwar Hashmi, Jun Zhang, Xiao-Liang Chen, Mahmood Hussain, I. Dhansingh, Shahid Siddiqui.
A new connectivity model for the locomotion network. Gal Haspel, Michael J. O'Donovan.
Contribution of LEV-8 Subunit to the Kinetics of Activation and Desensitization of C. elegans Muscle Levamisole-Sensitive Nicotinic Receptors. Guillermina S. Hernando, Diego H. Rayes, Cecilia B. Bouzat.
Braking fusion: synaptotagmin relieves the complexin block on synaptic release. RJ. Hobson, S. Watanabe, Q. Liu, EM. Jorgensen.
Microbial proton pumps as hyperpolarizers complement the optogenetics toolbox in Caenorhabditis elegans. Steven J. Husson, Jana F. Liewald, Jeffrey N. Stirman, Hang Lu, Alexander Gottschalk.
C. elegans mutants defective in neuropeptide amidation enzymes are abnormal in egg-laying behavior. Steven J. Husson, Liesbet Temmerman, Bart Landuyt, Ellen Meelkop, Niels Ringstad, H.Robert Horvitz, Alexander Gottschalk, Liliane Schoofs.
Integration of temperature signals in interneurons of C. elegans. Shingo Ikeda, Tsubasa Kimata, Ikue Mori.
Neuronal modeling toward quantitative understanding of nervous system of C. elegans. Yuishi Iwasaki, Masahiro Kuramochi, Kazumi Sakata, Shigekazu Oda, Yuichi Iino, Ryuzo Shingai.
Stress response to food depravation is modulated by non-synthesizing 5-HT neurons that absorb non-synaptic 5-HT, via 5-HT transporter, MOD-5/SERT, in C. elegans. Gholamali Jafari, Bin Liang, Andrey Kullyev, Ji Ying Sze.
Forward screen for mutants lacking a food block on olfactory adaptation. Laine Janzen, Amanda Cha, Ghazal Ghafari, Stephanie Summers, Sara Llamas, Pilar Stinson, Noelle L'Etoile, Jared Young.
Progress Towards a Reconstruction of a C. elegans Male Anterior Nervous System. T. Jarrell, Y. Wang, A. Bloniarz, M. Xu, C. Brittin, K. Nguyen, D. H. H. Hall, S. W. Emmons.
Temporal processing of olfactory information in C. elegans chemosensory neurons. Saul Kato, Yifan Xu, Christine Cho, L. F. Abbott, Cornelia Bargmann.
Characterization of the novel TOM-1 binding partner, VPS-39, in C. elegans. Susan M. Klosterman, Szi-Chieh Yu, Anna O. Burdina, Janet E. Richmond.
AGS-3 alters C. elegans behavior after food deprivation via RIC-8 activation of the neural G protein Gαo. Catherine Hofler, Michael Koelle.
Oxidative stress induces loss of GFP labeled neurons and delayed development to adulthood in an unc-13 mutant. Caitlyn McLarnon, Caitlin McGee, Lauren King, Christopher Frymoyer, Elizabeth Roth, Laura Gurenlian, Alicia N. Minniti, Nibaldo C. Inestrosa, Rebecca E. Kohn.
Investigation of Anaphase Promoting Complex Function in Regulating Synaptic Transmission at the C. elegans Neuromuscular Junction. Jennifer R. Kowalski, Hitesh Dube, Tina Jumani, Peter Juo.
An approach towards identification of cell recognition molecules involved in synapse specificity in the nematode Caenorhabditis elegans. Maria I. Lazaro-Pena, Adam Bloniarz, Travis Jarrell, Scott W. Emmons.
ABI-1 controls acetylcholine receptor clustering and rpy-1 expression level. Bo Yun Lee, Seugnhee Nam, Junho Lee.
Short-term synaptic depression and vesicle pool refilling at the C. elegans neuromuscular junction. Qiang Liu, Shigeki Watanabe, Erik Jorgensen.
C. briggsae puf-2 regulates pharyngeal muscle physiology and is essential for postembryonic development. Qinwen Liu, Eric Haag.
Screening for ACR-16 clustering mutants. Ashley A. Martin, Feyza Sancar, Janet E. Richmond.
The sup-1 gene encodes a novel transmembrane protein that interacts with the UNC-17 vesicular acetylcholine transporter in C. elegans. Ellie Mathews, Greg Mullen, Jonathan Hodgkin, Janet Duerr, Jim Rand.
C. elegans Presenilin Regulates Muscle Cell Excitability. Erin E. McClure, Ken R. Norman.
Epileptogenesis: Using C. elegans to elucidate the mechanism of a neural circuitry switch. Allyson V. McCormick, James H. Thomas, Brian C. Kraemer.
The DAF-7/TGF-β signaling pathway regulates the abundance of the glutamate receptor GLR-1 in the ventral nerve cord. Annette McGehee, Peter Juo.
Affinity Purification and Identification of Complexes of Interacting Proteins Directly from the C. elegans Nervous System. Christopher Hoover, Stacey Edwards, Michael Kinter, Caroline Kinter, Kenneth Miller.
Forward Genetic Analysis of Dense Core Vesicle Maturation and Function. Stacey Edwards, Christopher Hoover, Kenneth Miller.
Functional imaging of neuronal activity for 2-nonanone stimulation. Yosuke Miyanishi, Junichi Nakai, Kotaro Kimura.
The Novel Conserved Gene C44B9.1 Regulates C. elegans Behavior through G Protein Signaling and Likely Regulates Synaptic Vesicle Release. N. Paquin, A. Froehlich, D. Omura, H. R. Horvitz.
Mutants that fail to respond to exogenous serotonin identify new serotonin signaling genes. Judy S. Pepper, Michael R. Koelle.
An ADAMTS-Like protein is required for acetylcholine receptor localization. Berangere Pinan-Lucarre, Valerie Robert, Jean-Louis Bessereau.
ACR-12 receptor signaling complexes regulate motor circuit activity. Hilary Prescott, Marian Haburcak, Michael Francis.
A neuropeptide-mediated stretch response links muscle contraction to changes in neurotransmitter release. Zhitao Hu, Edward Pym, Kavita Babu, Amy Vashlishan Murray, Joshua Kaplan.
A Gq and CaMKII-dependent serotonergic circuit in C. elegans aversive olfactory learning. Yuqi Qin, Xiaodong Zhang, Yun Zhang.
Transgenic expression of mammalian neuroligin rescues the phenotypes of C. elegans neuroligin-deficient (nlg-1) mutants. Jerrod Hunter, Greg Mullen, Ellie Mathews, Jessica Heatherly, Jim Rand.
UNC-41/stonin functions with AP2 to recycle synaptic vesicles in C. elegans. Greg Mullen, Kiely Grundahl, Mingyu Gu, Shigeki Watanabe, Robert Hobson, John McManus, Ellie Mathews, Erik Jorgensen, Jim Rand.
The core apoptotic executioner proteins CED-3 and CED-4 promote initiation of neuronal regeneration in Caenorhabditis elegans. B. Pinan-Lucarre, C. V. Gabel, C. P. Reina, M. Driscoll.
Control of acetylcholine receptor maturation and ER homeostasis by a new transmembrane complex. Magali Richard, Thomas Boulin, Janet Richmond, Jean-Louis Bessereau.
Single-neuron photoactivation by cell-specific expression of Channelrhodopsin-2 using the cre-lox system to analyze habituation in sensory neural circuits. Cornelia Schmitt, Alexander Gottschalk.
Carbon dioxide avoidance is mediated by a diverse set of sensory neurons in C. elegans. Z. Soltesz, A. J. Bretscher, M. de Bono.
Notch signaling regulates synaptic transmission at the neuromuscular junction. Altar Sorkaç, Komudi Singh, Michael DiIorio, Anne Hart.
WDR-23 mediates synaptic transmission by regulating the transcription factor SKN-1 in motor neurons. Trisha Staab, Trevor Griffen, Derek Sieburth.
A conserved role of α-adducin (ADD-1) in memory, synaptic plasticity, and in AMPA-type glutamate receptor dynamics. Vanja Vukojevic, Leo Gschwind, Christian Vogler, Philippe Demougin, Dominique de Quervain, Andreas Papassotiropoulos, Attila Stetak.
Subcellular localization and protein interactions of PTL-1 in Caenorhabditis elegans. Kathleen M. Susman, Joshua Sturm, Celia McKee, Eunice Chou, Nancy J. Pokrywka.
New Approach in Systems Neuroscience in C.elegans. Hiroshi Suzuki.
MOD-5/SERT Function in 5-HT-absorbing Neurons Controls Behavioral Response to Food Deprivation. G. Jafari, Y. Xie, A. Kullyev, B. Liang, J. Sze.
A genome-wide RNAi screen for levamisole sensitivity identifies new regulators of post-synaptic signaling. Jessica E. Tanis, Timothy Chaya, Todd Lamitina.
Gustatory plasticity in C. elegans involves sensitisation of ASH nociceptive neuron and desensitisation of ASE gustatory neuron. Oluwatoroti Umuerri, Martijn Dekkers, Gert Jansen.
Modulation of Neuropeptide Release by Locomotion. Amy B. Vashlishan Murray, Kavita Babu, Edward C. G. Pym, Zhitao Hu, Joshua M. Kaplan.
An Open-Source Neuromechanical Model of C. Elegans Locomotion. Thomas Voegtlin, Netta Cohen.
Regulation of a rhythmic behavior in C. elegans by neuropeptide signaling. Han Wang, Kelly Girskis, Krishnakali Dasgupta, Derek Sieburth.
The Role of Nicotinic Acetylcholine Receptors in Antipsychotic-induced Phenotypes in Caenorhabditis elegans. T. Xu, X. Wang, L. Hao, BM Cohen, EN Buttner.
Genetic analysis of acute ethanol responsive behaviors in C. elegans. Joseph Alaimo, Keith Shelton, Andrew Davies, Jill Bettinger.
Calcium-dependent regulation of proton signaling during a rhythmic behavior in C. elegans. Erik Allman, Keith Nehrke.
Investigating neural coding and interacting circuits. Evan L. Ardiel, Andrew C. Giles, Ithai Rabinowitch, William R. Schafer, Catharine H. Rankin.
A Possible Role for nhr-239 in Sensory Response. G. Michael Baer, Christopher Alvaro, Benjamin Perlman, Bruce Wightman.
Characterization of an evolutionary conserved vasopressin/oxytocin-like signaling system in C. elegans. Isabel Beets, Ellen Meelkop, Liesbet Temmerman, Tom Janssen, Marleen Lindemans, Liliane Schoofs.
A role for heterochronic genes in regulating C.elegans quiescence. Heather L. Bennett, Komudi Singh, Edward Anderson, Mark E. Corkins, Anne C. Hart.
Membrane lipid environment is important for the development of acute functional tolerance to ethanol. Jill C. Bettinger, Mia H. Bolling, Kapo Leung, Joseph T. Alaimo, Andrew G. Davies.
Huffing and drinking are not the same: Screening for targets of toluene and ethanol. Ryan I. Friedberg, ChungLung Chan, Hersh Gupta, Victoria E. Brings, Charlotte M. Wincott, Keith L. Shelton, Jill C. Bettinger, Andrew G. Davies.
Lethargus is a highly regulated behavior, characterized by quiescence- and motion-bouts and a typical posture. S. Iwanir, S. Nagy, N. Tramm, C. Wright, D. Biron.
Spontaneous recovery from habituation to tap is interstimulus interval-dependent. Ricardo Bortolon, Catharine H. Rankin.
A C. elegans movement assay for the assessment of neurotoxicity and genetic mutations. Windy A. Boyd, Daniel W. Snyder, Grace E. Kissling, Jonathan H. Freedman.
Maintenance of the identity of the chemosensitive BAG neurons requires an ETS family transcription factor. Julia P. Brandt, Sonya Aziz-Zaman, Jennifer K. Lee, Niels Ringstad.
Perception of bacteria by the AWC neuron. Chantal Brueggemann, Damien O'Halloran, Noelle L'Etoile.
Samamide is a new small-molecule probe of behavioural quiescence in C. elegans. Andrew R. Burns, Suji Tharmalingalam, William S. Ryu, Sean R. Cutler, David R. Hampson, Peter J. Roy.
Spatial memory in C. Elegans. Adam Calhoun, Tatyana Sharpee, Sreekanth Chalasani.
The paraoxonase-like protein K11E4.3 is needed for gentle touch and mec-4(d)-mediated neurodegeneration. Yushu Chen, Martin Chalfie.
Characterization of Electrotaxis Behavior in C. elegans. Steven D. Chrisman, Eric Foss, Lucinda Carnell.
The rescue of ODR-1. Kimberly D. Collins.
Dopaminergic receptor signaling in sex-muscles antagonizes cholinergic induced excitability post-eyaculation during male mating of C. elegans. Paola Correa, Garcia Rene.
Dissecting predator/prey interactions in C. elegans. Kevin Curran, Ray Hong, Sreekanth Chalasani.
Uncovering the molecular basis for ethanol activation of the BK channel using random mutagenesis. Scott J. Davis, Sam Song, Kelly Milman, Jon Pierce-Shimomura.
Behavioral characterization of BTBD9 homolog knockout in C.elegans. Atbin Doroodchi, Mark DeAndrade, Anthony Bucolo, Michael Miller, Charles Amsler, Qiang Ding, Yuqing Li.
The functional importance of the MEC-4 transmembrane domain in force activation of the channel. Amy L. Eastwood, Miriam B. Goodman.
Innexin gene inx-4 mutant is defective in thermotaxis. Taishi Emmei, Nana Nishio, Hiroyuki Sasakura, Mari Akasaka, Ikue Mori.
Overexpression of APL-1 disrupts learning via the insulin/IGF-1 and TGF-β pathway. Collin Ewald, Ruby Cheng, Lana Tolen, Vishal Shah, Aneela Gillani, Afsana Nasrin, Chris Li.
Modeling neuron, circuit and biology of Caenorhabditis elegans leads to a digital worm that conducts automatic locomotion, providing testable hypothesis regarding reversal control. Shijie Zhang, Beverly Piggot, Wei Jin, Shawn Xu, Jiong Yang, Zhaoyang Feng.
Role of the 5-HT1 receptor homolog, ser-4, and the CREB homolog, crh-1, in behavioral adaptation to chronic activation of serotonergic pathways in C. elegans. Eric Foss, Lucinda Carnell.
Chemotaxis behavior is regulated by germline in C. elegans. M. Fujiwara, N. Sato, S. Maruyama, T. Akamine, T. Ishihara.
Automated and Quantitative Method to Identify Satiety Quiescence by Locomotion. Thomas L. Gallagher, Young-jai You.
Quantitative genetic dissection of a behavioral sequence in C. elegans. Rajarshi Ghosh, William S. Ryu, Leonid Kruglyak.
Secondary Allele Screen for Extreme Habituation Phenotypes after High Throughput Behavioral Characterization of a Nervous-system-biased Mutant Library. Andrew C. Giles, Nicholas A. Swierczek, Rex A. Kerr, Catharine H. Rankin.
Male mating potency decline during adulthood is correlated with the increase of sex muscles excitability in C. elegans. Xiaoyan Guo, Rene Garcia.
Another PKG: C09G4.2. Anu Gupta.
Candidate mediators of the food block on olfactory adaptation. Paula M. Gutierrez, Jared Young, Joshua Braslow, Noelle L’Etoile.
The Effect of Hermaphrodite Sperm Status on C. elegans Sexual Attraction. Leonard A. Haas, Natalia Morsci, Maureen Barr.
Antipsychotic drug-induced developmental delay and lethality require the sphingomyelin synthase gene sms-1. L. Hao, B. Cohen, E. Buttner.
TYRA-3 mediates the tyraminergic inhibition of 5-HT-stimulated aversive responses in Caenorhabditis elegans. Vera M. Hapiak, A. Stein, A. Korchnak, R. W. Komuniecki.
Oriental Beetle Pheromone Insensitive Mutants in Pristionchus pacificus. Jonathan Yaghoobian, Jessica Ciinkornpumin, Judy Salandanan, Neomal Muthumala, Jeffrey Shibata, Christoph Dieterich, Ray Hong.
Molecular mechanism governing interaction between nematodes and nematophagous fungi. Yen-Ping Hsueh, Erich Schwarz, Ry Forseth, Frank Schroeder, Paul Sternberg.
An RNAi screen for defecation mutants. Andrew Burns, Lois Immerman, Jessica Bennett, Latarsha Porscher, Samuel McCright, Hillary Mullan, Monica Raible, Matthew Miller, Maureen Peters.
CRF receptor-like GPCR mediated stress response and regulates behavioral states in C. elegans. Changhoon Jee, Jungsoo Lee, Steven McIntire, L. René García.
EGL-19, UNC-36 and CCB-1 underlie voltage-dependent calcium currents in C. elegans striated muscle. Viviane Lainé, Christian Frřkjćr Jensen, Maëlle Jospin.
CNP-2 (Calcineurin Interacting Protein-2) modulates calcineurin activity in Caenorhabditis elegans. Hana Jung, Hyun-Ok Song, Weixun Li, Sunkyung Lee, Joohong Ahnn.
Role of ER resident proteins Calnexin and Calreticulin in Chemosensory Behavior in C. elegans. Karunambigai Kalichamy, Sunkyung Lee, Joohong Ahnn.
C. elegans locomotory pattern, pausing frequency and speed is regulated by the CEP sheath glia. Menachem Katz, Francis Corson, Shai Shaham.
Biomechanical analysis of C. elegans locomotion. Daeyeon Kim, Jin-Sung Park, David Weitz, Jennifer H. Shin.
Food Size and cGMP Affects Feeding Behavior in Pristionchus pacificus. Silvina Kroetz, Ray Hong.
Analysis of temperature memory in cultured thermosensory neuron AFD of C. elegans. K. Kobayashi, I. Mori.
A Deletion Mutation of the C. elegans CaMKII Gene unc-43 Inhibits Associative Conditioning and Modulates Non-Associative Conditioning. Sara M. Knauft, Robert M. Bragg, Jade R. Brusseau, Jacqueline K. Rose.
Experience-dependent modulation of salt preference in C. elegans. Hirofumi Kunitomo, Ryo Iwata, Hirofumi Sato, Hayao Ohno, Yuichi Iino.
The Ca2+-binding C2 domain of PKC-2 couples thermal activation of TAX-2/TAX4 to C. elegans behavior. Marianne Land, Charles Rubin.
Do ascarosides affect egg-laying behavior in Caenorhabditis elegans? Circe Lassegue, Ramadan Ajredini, Rathika Nimalendran, Arthur Edison.
K+ channel interplay modifies male mating response. Brigitte L. LeBoeuf, L. Rene Garcia.
Tracing the genetic basis of the nictation behavior by QTL mapping. Daehan Lee, Junho Lee.
Neuronal Regulation of Nictation Behavior in Caenorhabditis elegans. Harksun Lee, Myung-kyu Choi, Daehan Lee, Hye-sung Kim, Hyejin Hwang, Heekyeong Kim, Sungsu Park, Young-ki Paik, Junho Lee.
STR-33, a novel G protein-coupled receptor that regulates locomotion and egg-laying in Caenorhabditis elegans. J. E. Lee, P. Y. Jeong, H. J. Joo, H. Kim, T. H. Lee, H. Koo, Y. K. Paik.
Identification of Genes that Mediate Ethanol-Induced Acute Functional Tolerance in C. elegans. Ka-Po Leung, Mia Bolling, Gina Blackwell, Jennifer Gardner, Andrew Davies, Jill Bettinger.
Genetic and molecular investigation of PKD-2 and LOV-1 involved in male C. elegans perception of sex pheromone. Rachel C. K. Li, King L. Chow.
The neural circuits underlying harsh touch sensation in C. elegans. Wei Li, Lijun Kang, Beverly Piggott, Zhaoyang Feng, Shawn Xu.
The robustness of C. elegans male mating behavior depends on the distributed properties of ray sensory neurons and their output through core and male-specific targets. Pamela Koo, Xuelin Bian, Amrita Sherlekar, Meredith Bunkers, Robyn Lints.
Candidate screen for mutants defective in long-term memory of habituation. Andrea McEwan, Catharine Rankin.
Humoral Cholinergic Signaling Augments Male Reproductive Motivation. James T. Midkiff.
Screen to identify mutants that fail to adapt to the inhibitory effects of serotonin on locomotory behavior. Spencer Moen, Eric Foss, Lucinda Carnell.
Assessing the neurotoxic effects of microcystins by developing a simple C. elegans model. Caroline Moore, Noelle L'Etoile, Birgit Puschner.
Coordinated neural and mechanical modifications regulate sexual variation in C. elegans locomotor behavior. William R. Mowrey, Douglas S. Portman.
Isolation and analysis of dauer pheromone response-defective (phd) mutants. Scott J. Neal, Kyuhyung Kim, Rebecca A. Butcher, Frank C. Schroeder, Piali Sengupta.
The role of cilia in cGMP signaling in the AFD thermosensory neuron. Phuong Anh T. Nguyen, Jacque-Lynne Johnson, Michel R. Leroux.
Analysis of molecular basis for thermotactic behavior regulated by CREB in Caenorhabditis elegans. Yukuo Nishida, Takuma Sugi, Mayu Nonomura, Ikue Mori.
Appetitive olfactory learning and associative long-term memory in C. elegans . Saori Nishijima, Ichiro Maruyama.
Quantitative analysis of exploratory patterns during thermotaxis. Yuta Ochiai, Yuki Tsukada, Ikue Mori.
Biased motion in unbiased environments: are the worms navigating? Margherita Peliti, John Chuang, Stanislas Leibler, Shai Shaham.
A calcineurin homologous protein is required for multiple sodium-proton exchange events in the C. elegans intestine. Jamie Wagner, Erik Allman, Ashley Taylor, Kiri Ulmschneider, Timothy Kovanda, Bryne Ulmschneider, Keith Nehrke, Maureen Peters.
Influence of Body Mechanics on Force Thresholds for Touch Sensation in C. elegans. Bryan C. Petzold, Sung-Jin Park, Miriam B. Goodman, Beth L. Pruitt.
Mammalian rhodopsin can functionally substitute for C. elegans photoreceptor to restore light sensitivity in worms. Beverly J. Piggott, Jingwei Gao, Jie Liu, X. Z. Shawn Xu.
Hypoxia avoidance response in C. elegans requires goa-1 and dgk-1. Jason N. Pitt, Mark B. Roth.
Is lethargus essential? David M. Raizen, Robert J. Driver, Annesia L. Lamb.
Uncovering the molecular and cellular basis for hygrosensation in C. elegans. Josh Russell, Jon Pierce-Shimomura.
Sexual identity of core neuronal circuitry modulates sex-specific behaviors in C. elegans. Renee M. Miller, Deborah A. Ryan, Kelli Fagan, Douglas S. Portman.
C. elegans uses distinct molecular mechanisms to respond to thermal impulse stimuli of different amplitudes. Rajarshi Ghosh, Aylia Mohammadi, Leonid Kruglyak, William S. Ryu.
Microfluidics approach to study neurodegeneration in a Caenorhabditis elegans Parkinson's disease model. Sangeena Salam, Pouya Rezai, P. Ravi Selvaganapathy, Bhagwati P. Gupta.
How worms move up and down salt gradients. L. Luo, M. Hendricks, Y. Zhang, A. Samuel.
Exploring the Function of TRF-1 in Polycystin-Expressing Sensory Neurons. Dianaliz Santiago-Martinez, Maria Gravato-Nobre, Jonathan Hodgkin, Maureen M. Barr.
Regulation of thermosensation by SRTX-1(GPCR) in AFD thermosensory neurons. Hiroyuki Sasakura, Keita Suzuki, Hiroko Itoh, Ikue Mori.
High alkaline pH sensation in C. elegans. Toshihiro Sassa, Takashi Murayama, Ichiro Maruyama.
Experience-dependent modulation of the neuronal response in the gustatory circuit. Hirofumi Sato, Hirofumi Kunitomo, Shigekazu Oda, Yuichi Iino.
Changes in responsivity of olfactory neurons to odor during olfactory adaptation and recovery in Caenorhabditis elegans . E. Sawatari, A. Inoue, T. Teramoto, T. Ishihara.
Mapping the neural circuits that function downstream of the sensory rays in C. elegans male mating behavior. Amrita Sherlekar, Pamela Koo, Xuelin Bian, Robyn Lints.
Notch signaling regulates chemosensation and behavioral adaptation to stress. Komudi Singh, Anne C. Hart.
Notch signaling regulates many aspects of quiescence during C. elegans lethargus. Komudi Singh, Heather L. Bennett, Altar Sorkac, Michael A. Dilorio, Anne C. Hart.
Variation in temperature-dependent behaviours among natural isolates of Caenorhabditis briggsae. Gregory Stegeman, Jiwon Shin, Nan Lin, Matthew Bueno De Mesquita, Asher Cutter, William Ryu.
Temporal and molecular characterization of short-term associative memory in C. elegans. Geneva M. Stein, Amanda L. Kauffman, Coleen T. Murphy.
Regulation of behavioral plasticity by systemic temperature perception in Caenorhabditis elegans. Takuma Sugi, Yukuo Nishida, Ikue Mori.
Bold TextEffects of ionizing radiation on pharyngeal pumping in Caenorhabditis elegans. Michiyo Suzuki, Tetsuya Sakashita, Yuya Hattori, Toshio Tsuji, Yasuhiko Kobayashi.
Revealing the promiscuous nature of pigment dispersing factor signaling. Liesbet Temmerman, Ellen Meelkop, Annelies Bogaerts, Liliane Schoofs, Tom Janssen.
Analysis of molecular mechanisms that integrate sensory perception of nutrient with rhythmic motor output. Baskaran Thyagarajan, Keith W. Nehrke.
Ca2+-CaM-dependent protein Kinase I is required for short- and long-term mechanosensory habituation. Tiffany A. Timbers, Jing Xu, Catharine H. Rankin.
Role of dopamine in locomotory transitions in C. elegans. S. Topper, A. Vidal-Gadea, L. Young, A. Gottschalk, J. Pierce-Shimomura.
Molecular mechanism of salt taste. Oluwatoroti Umuerri, Gert Jansen.
Glial regulation of chemosensation. Sean W. Wallace, Shai Shaham.
GRK-2 regulates serotonin metabolism and egg-laying behavior in C. elegans. Jianjun Wang, Jiansong Luo, Dipendra Aryal, William Wetsel, Jeffrey Benovic.
Bending waves during C. elegans locomotion are driven by proprioceptive coupling. Quan Wen, Elizabeth Hulme, Sway Chen, Xinyu Liu, Marc Gershow, Andrew Leifer, Victoria Butler, Christopher Fang-Yen, William Schafer, George Whitesides, Matthieu Wyart, Dmitri Chklovskii, Aravinthan Samuel.
Acetylcholine-Gated Chloride Channels (ACCs) may be involved in development and behaviour, suggesting a central role for fast inhibitory cholinergic neurotransmission in C.elegans. Claudia M. Wever, Patrick Janukavicius, Jin-Kyung Chang, Danielle Farrington, Julian Gitelman, Igor Putrenko, Joseph A. Dent.
In vivo structure-function analysis of C. elegans GRK-2. Jordan Wood, Jeffrey Benovic, Denise Ferkey.
Worms maintain their response to the repulsive odor 2-nonanone during avoidance behavior. Akiko Yamazoe, Yuishi Iwasaki, Kotaro Kimura.
Olfactory preference switch depending on odor concentration is mediated by combinatorial change of acting sensory neurons. K. Yoshida, T. Hirotsu, T. Tagawa, S. Oda, Y. Iino, T. Ishihara.
Calcium-activated chloride channels (CaCCs) act as ciliary sensory receptors in C.elegans. Yuxia Zhang, Jinghua Hu.
Development and Evolution: Cell fate patterning (embryonic and postembryonic)
Two homeodomain transcription factors, MLS-2 and CEH-6, promote tube development in the excretory system. Ishmail Abdus-Saboor, Craig Stone, John Murray, Meera Sundaram.
The C. elegans Wnt Effector TCF/LEF/POP-1 Acts to Protect the Signalled Fate by Restricting β-catenin/WRM-1 to the Nucleus in Stem-Like Seam Cells. Peter J. Appleford, Charles Brabin, Alison Woollard.
A focused reverse genetic screen for regulators of Distal Tip Cell specification. Austin T. Baldwin, Bryan T. Phillips.
Towards a quantitative understanding of the vulva cell fate patterning network. Michalis Barkoulas, Marie-Anne Félix.
gad-1 RNAi Leads to a General Increase in Cell Lifetimes During Development. Max E. Boeck, Robert Waterston.
A regulatory network of homeobox genes is required for the function of the Caenorhabditis elegans excretory cell. Yong-Guang Tong, Krai Meemon, Thomas R. Burglin.
A Genetic Screen for Kinases regulating Body Size with calcineurin in C. elegans.. Tae-Woo Choi, Joohong Ahnn.
Identification of genes that genetically interact with pha-4/FoxA to regulate pharynx development. Youngeun Choi, Trisha J. Brock, Dustin L. Updike, Susan E. Mango.
Interaction of TGFβ regulators, LON-1 and LON-2 with its downstream target, DBL-1. Y. J. Ang, J. C. C. Lee, C. K. H. Wong, M. Mok, K. L. Chow.
Geometric modeling of C. elegans vulval patterning. Francis Corson, Eric Siggia.
Dormant Self-renewal Program of C. elegans Early Blastomeres Controlled by Protein Turnover. Zhuo Du, Anthony Santella, Zhirong Bao.
Use of Single-molecule FISH To Determine Expression Patterns and Functions of C. elegans Lysine Methyltransferases. Christoph G. Engert, Alexander van Oudenaarden, Bob Horvitz.
Multiple Routes to Suppressing aph-1(zu147) Embryonic Lethality. Victoria Fang, Valerie Hale, Caroline Goutte.
Rab-8 functions to mediate excretory cell development in C. elegans. D. A. Fantz, K. Kornfeld, D. Smith.
Identification and characterization of cell type-specific Wnt pathway-regulated genes in C. elegans. Lakshmi Gorrepati, David. M. Eisenmann.
Exploring Presenilin Differences in C. elegans. Caitlin Greskovich, Rebecca Resnick, Valerie Hale, Caroline Goutte.
Environmental flexibility of the genetic network underlying C. elegans vulval development. Stephanie Grimbert, Christian Braendle.
A role of the LIN-12/Notch signaling pathway in diversifying the non-striated egg-laying muscles in C. elegans. Jared Hale, Carolyn George, Leila Toulabi, Zachary Via, Nirav Amin, Jun Liu.
Single-blastomere transcriptomics elucidates the C. elegans E-lineage gene regulatory network. Tamar Hashimshony, Florian Wagner, Itai Yanai.
Identification of genes that function with dsh-2 to regulate asymmetric cell division. Kyla Hingwing, Tammy Wong, Jack Chen, Nancy Hawkins.
Distinct protein domains regulate stability and patterning of MEX-3 in the C. elegans embryo. Nancy N. Huang, Craig P. Hunter.
The CEH-20/UNC-62 transcriptional partnership regulate seam cell proliferation by controlling division asymmetry. Samantha L. Hughes, Charles Brabin, Alison Woollard.
Geometric Comparisons of the EMS Blastomere in Caenorhabditis elegans and C. briggsae. Corey R. Johnson, Scott Thatcher, Timothy D. Walston.
Transcriptional control of dorsal-ventral polarity. Rossio K. Kersey, Thomas Brodigan, Tetsu Fukushige, Michael Krause.
Study on localization mechanisms of maternal mex-3 mRNA. Hiroyuki Konno, Koki Noguchi, Yuji Kohara.
Region II of the C. elegans Transcription Factor LIN-31: Site-Directed Mutagenesis and Transcription Assay Development. Sarah Mathes, Leilani Miller.
Role of PHA-4/FoxA binding in cell fate specification during organogenesis. Christina K. McPhee, Susan E. Mango.
ACE-like non-peptidase (acn-1) as a new suppressor of let-7. Chanatip Metheetrairut, Frank Slack.
Understanding the Role of MAP Kinase Phosphorylation in C. elegans Cell Signaling. Fernando Meza Gutierrez, Misbah Palla, Leilani Miller.
Mutational and yeast two-hybrid analysis of the C. elegans winged-helix transcription factor LIN-31 reveal functionally-distinct domains. Corey Morris, David Doroquez, Scott Montgomery, E. Lorena Mora-Blanco, Misbah Palla, Leilani Miller.
RalGEF (RGL-1) signaling performs dual/antagonistic functions in vulval patterning. Kimberly B. Monahan, Tanya P. Zand, Channing J. Der, David J. Reiner.
Automated phenotyping of Caenorhabditis elegans embryogenesis at the single cell and cellular group levels. Julia Moore, Zhou Du, Anthony Santella, Christian Pohl, Zhirong Bao.
Regulation of Asymmetric Seam Cell Division by the Non-Receptor Tyrosine Kinase, FRK-1, during Post-embryonic Development in Caenorhabditis elegans. Kelsey Moore, James Bour, Sherri Smith, Aaron P. Putzke.
Genetic analysis of vulval development in Caenorhabditis briggsae. Devika Sharanya P. Premkumar, Bavithra Thillainathan, Bhagwati P. Gupta.
Screening for Inhibitors of Cellular Reprogramming. Tulsi Patel, Baris Tursun, Dylan Rahe, Oliver Hobert.
Components that Transduce Extracellular Matrix Signals Are Required for Developmental Commitment of C. elegans Embryonic Progenitor Cells. Misty R. Riddle, Nareg J. Djabrayan, Joel H. Rothman.
The chromo-helicase domain protein CHD-7 is a putative regulator of WNT-ligands. Daniel Roiz Lafuente, Ivo Rimann, Steffanie Nusser-Stein, Alex Hajnal.
Evolution of embryonic development in nematodes. Jens Schulze, Einhard Schierenberg.
Plectus - a stepping stone in embryonic cell lineage evolution of nematodes. Jens Schulze, Jana Uenk, Einhard Schierenberg.
The Panacea Consortium: Identification of new Modulators of EGFR/RAS/MAPK and WNT signaling during vulval development. Tobias Schmid, Fabienne Largey, Alex Hajnal.
The histone acetylation, methylation, and H2A.z are involved in the maintenance of cell fates in C. elegans. Yukimasa Shibata, Hitoshi Sawa, Kiyoji Nishiwaki.
The β-catenin HMP-2 functions downstream of Src in parallel with the Wnt pathway in early embryogenesis of C. elegans. Eisuke Sumiyoshi, Sachiko Takahashi, Hatsue Obata, Asako Sugimoto, Yuji Kohara.
Nhr-67/tailless Functions in the AC-VU Decision, AC Differentiation, and Expression of lin-12 in the pre-VU Cells. Tara Tappen, Lauren Pioppo, Brittany Sanford, Jenny Hall, George McClung, Rachel Summer, Alex Breiding, Sheila Clever, Bruce Wightman.
Quantifying gene expression dynamics of LIN-3/EGF targets during vulva induction. Jeroen S. van Zon, Alexander van Oudenaarden.
RNAi screening in Caenorhabditis elegans Ras mutant identified blmp-1 as a putative Ras cooperating tumor suppressor gene. Nattha Wannissorn, Andy Fraser.
Comparing gene expression pattern in the skn-1 intestinal developmental network in C. briggsae, C. remanei, and C. elegans to gain insights into the dynamical functional roles of orthologous genes. Allison Wu, Lawrence Du, Scott Rifkin.
Direct in vivo Cellular Reprogramming Involves Transition Through Discrete, Non-Pluripotent Steps. S. Zuryn, J. P. Richard, N. Fischer, V. Pavet, N. Vaucamps, S. Jarriault.
Development and Evolution: Cell death and neurodegeneration
Genome wide RNAi screen to study uv1 cell necrosis. Awani Awani, Matt Crook, Wendy Hanna-Rose.
Apoptosis-mediated toxicity of water stable carbon nanoparticles in Caenorhabditis elegans . Shin S. Choi, Yoon J. Cha.
Exploring alternative means to induce axonal injury in C. elegans neurons. Sean Coakley, Massimo A. Hilliard.
Neuron specific knock-down of smn-1 causes neuronal degeneration and death. I. Gallotta, P. Bazzicalupo, E. Di Schiavi.
Elucidating the genetic and molecular mechanisms underlying smn-1 synaptic defects. M. Dimitriadi, G. Kalloo, A. C. Hart.
vha-12, a catalytic subunit of the V-ATPase, is required for apoptotic corpse clearance. Glen Ernstrom, Robby Weimer, David Greenstein, Erik Jorgensen.
Identification of modulators of RNA-dependent toxicity in Myotonic Dystrophy. Susana M. Garcia, Guinevere F. Lourenço, Gary B. Ruvkun.
Growth cone guidance receptors modulate mitochondrial morphology and function via a secreted moiety of the VAPB/ALS8 protein, the major sperm protein domain. S. Han, H. Tsuda, Y. Yang, J. Vibbert, P. Cottee, C. Haueter, J. Prasain, H. J. Bellen, M. A. Miller.
The Sp1 Family Transcription Factor SPTF-3 Promotes M4 Sister Cell Death through egl-1 Expression in the M4 Sister Cell. Takashi Hirose, Bob Horvitz.
sli-1 Cbl Opposes the Engulfment of Apoptotic Cells. Michael E. Hurwitz, Courtney Anderson, Bob Horvitz.
A Screen for Genes Involved in Engulfment-Dependent Cell Death. Holly L. Johnsen, H. R. Horvitz.
In vitro and in vivo investigation of modulators of hyperactivated ion channel induced necrosis in C. elegans. Shaunak Kamat, Shrutika Yeola, Wenying Zhang, Monica Driscoll.
Genetic Control of Neurodegeneration by an Evolutionary-conserved Heterotrimeric G Protein Signaling Pathway. Bwarenaba B. Kautu, Matthew L. Hicks, Adam J. Harrington, Kim A. Caldwell, Guy A. Caldwell.
An MLL-type H3K4 methyltransferase complex is required for linker cell death. Maxime J. Kinet, Shai Shaham.
Specific small heat shock proteins regulate calcium homeostasis in the medial Golgi to protect against necrotic cell death. Nikos Kourtis, Nektarios Tavernarakis.
Starvation induces a global translational arrest that triggers germ cell apoptosis. Laura Láscarez, Carlos G. Silva-García, Tzvetanka D. Dinkova, Rosa E. Navarro.
Secreted VAPB/ALS8 major sperm protein domains regulate mitochondrial fusion and fission machinery localization in body wall muscle. S. Lee, M. Miller.
Controlling protease-driven lysosomal dependent "necrotic" cell death and beyond. Cliff J. Luke, Mark M. Miedel, Sangeeta R. Bhatia, Nathan J. Graf, Gary A. Silverman.
The Role of Carbonic Anhydrase in Mediating Cell Stress Response following Neuronal Injury. T. A. Matthews, G. V. W. Johnson-Voll, K. W. Nehrke.
Improved Alzheimers Disease Model of Aβ1-42 toxicity. Gawain McColl, Blaine Roberts, Adam Gunn, Tara Pukala, Christine Roberts, Christopher Link, Robert Cherny, Ashley Bush.
Utilization of alternative mRNA forms for CED-4/Apaf-1 during germ cell apoptosis. J. Kaitlin Morrison, Vince Contreras, Enhui Hao, Brett D. Keiper.
Role of dynein light chain 1 in apoptosis: Using C. elegans as a model system. Tine H. Mřller, Anders Olsen.
Identification and characterisation of genes essential for axonal maintenance. Brent Neumann, Massimo A. Hilliard.
Effects of the Wlds mutation on axonal degeneration and regeneration in C. elegans neurons. Annika L. A. Nichols, Brent Neumann, Massimo A. Hilliard.
Serotonergic blockade prevents age-related neurodegeneration in C. elegans model of Alzheimers disease. Jonathan T. Pierce-Shimomura, Ashley Crisp.
The localization of CED-9/Bcl2 and CED-4/Apaf-1 is not consistent with the accepted model for C. elegans apoptosis induction. Ehsan Pourkarimi, Sebastian Greiss, Anton Gartner.
Characterizing an uncharacterized protein: F16A11.2, a neuroprotective gene product with a putative role in RNA localization. Arpita Ray, Susan M. DeLeon, Kim A. Caldwell, Guy A. Caldwell.
Mild Frataxin suppression reduces fat accumulation, induces autophagy and protects from motility defects in C. elegans. Alfonso Schiavi, Alessandro Torgovnick, Evgenia Megalou, Nektarios Tavernarakis, Roberto Testi, Natascia Ventura.
The RNA binding protein TIA-1.2 promotes stress-induced germ cell apoptosis and regulates granules assembly in the gonad core. Carlos Silva, Jorge Ramírez, Valerie Reinke, Rosa E. Navarro.
gex Complex Genes Are Involved in the Engulfment of Apoptotic Cells. E. Simionato, M. E. Hurwitz.
Establishing a RIP-seq method to study the role of RNA-binding proteins in germ cell apoptosis. Deni Subasic, Jochen Imig, Marko Jovanovic, Jonathan Hall, Andre Gerber, Michael Hengartner.
Modulation of stroke-like neurodegeneration by cell stress-resistance signaling pathways. . Nazila Tehrani, John Del Rosario, Moises Domingues, Itzhak Mano.
Clathrin-mediated endocytosis and intracellular trafficking are required for necrotic cell death in C. elegans. Kostoula Troulinaki, Nektarios Tavernarakis.
Investigation of the neuroprotective role of GIPC in a C. elegans model of Parkinsons Disease. Michelle L. Tucci, Laura A. Berkowitz, Kim A. Caldwell, Guy A. Caldwell.
Axonal Degeneration in C. elegans motor neurons: a model for Motor Neurone Disease. Nicholas J. Valmas, Ivan Cáceras, Hang Lu, Massimo A. Hilliard.
Identification and characterization of molecular modulators of methylmercury-induced whole animal and dopamine neuron pathology in C. elegans. Natalia VanDuyn, Raja Settivari, Gary Sinclair, Richard Nass.
The role of plastin in Spinal Muscular Atrophy. Melissa Walsh, Anne Hart.
Caenorhabditis elegans O-GlcNAc cycling mutants alter the proteotoxicity of models of human neurodegenerative disorders. Peng Wang, Brooke Lazarus, Michele Forsythe, Dona Love, Michael Krause, John Hanover.
Analysis of cellular toxicity mechanisms of alpha-synuclein in C. elegans. Nora Wender, Jan Hegermann, Stefan Eimer.
Transgenic Caenorhabditis elegans expressing Alzheimers pathway proteins to produce β-amyloid toxicity. Michael L. Wood, Anne Hart.
Identification of genetic modifiers for amyloid-beta toxicity in a C. elegans Alzheimers disease model. Xiaohui Yan, Adam Knight, Kim Caldwell, Guy Caldwell.
Dysfunctional LRRK2/p38 signaling in response to ER stress leads to dopaminergic neurodegeneration. Y. Yuan, P. Cao, M. Smith, K. Kramp, Y. Huang, X. Zhu, S. Siedlak, N. Hisamoto, K. Matsumoto, M. Hatzoglou, H. Jin, Z. Feng.
A genetic screen for modulators of apoptosis and engulfment in C. elegans. Sheng Zeng, Michael O. Hengartner.
Role of Nrf2/SKN-1 dependent and ER stress proteins in C. elegans models of Parkinsons disease and manganism. Raja Settivari, Shaoyu Zhou, Natalia VanDuyn, Jennifer LeVora, Gary Sinclair, Richard Nass.
Development and Evolution: Development timing
How do lin-28 and lin-46 regulate hbl-1? Jennifer Alaimo, Kevin Kemper, Bhaskar Vadla, Eric Moss.
Deciphering the role of the tumour suppressor PAR-4/LKB-1 in cell cycle regulation and asymmetric cell division. Laura Benkemoun, Julien Burger, Nicolas Chartier, Lionel Pintard, Jean-Claude Labbé.
Temporal regulation of rnt-1 in seam stem cell divisions by heterochronic let-7 family miRNAs. Rachael Nimmo, Toby Braun, Frank Slack, Alison Woollard.
The mir-51 family of microRNAs antagonizes multiple microRNA-mediated developmental pathways. John L. Brenner, Benedict J. Kemp, Allison L. Abbott.
Examining the kinetics of chromatin modifications associated with dosage compensation onset. Laura Custer, Györgyi Csankovszki.
Function of AMPK during the L1 diapause in C.elegans. Emilie Demoinet, Julie Mantovani, Richard Roy.
C. elegans body size is regulated by TGF-β signalling in multiple tissues. Aidan Dineen, Jeb Gaudet.
A genome-wide RNAi screen for let-7 suppressors identifies novel players in the heterochronic pathway. Matyas Ecsedi, Magdalene Rausch, Helge Grosshans.
Identification of heterochronic genes that suppress over-expression of mir-48, a let-7 family miRNA. Theresa L. B. Edelman, Tamar D. Resnick, Sarah Malmquist, Ann E. Rougvie.
WNK-1 negatively regulates formation of diacylglycerol in C. elegans. Takashi Fukuzono, Kunihiro Matsumoto, Naoki Hisamoto.
Heterochronic genes and Wnt pathway components regulate asymmetric division and cell fate of epidermal stem cells in C. elegans. Omid F. Harandi, Victor Ambros.
The male tail tip heterochronic regulatory network. R. Antonio Herrera, Karin Kiontke, Matthew D. Nelson, Ji-Sup Yang, David H. A. Fitch.
Mechanisms that maintain or re-establish VPC multipotency in dauer larvae. Xantha Karp, Iva Greenwald.
Comparative transcriptomics in five Caenorhabditis species reveals a unique embryonic milestone. Michal Levin, Tamar Hashimshony, Itai Yanai.
The C. elegans period homolog lin-42 regulates developmental timing and molting. Katherine A. McCulloch, Angela Barr, Ann E. Rougvie.
ECM Dynamics in the Molting Cycle. Vijaykumar Meli, Alison Frand.
Regulation and function of the let-7-related miRNA miR-48 in developmental timing. Tamar D. Resnick, Brittany Werre, Ann E. Rougvie.
mir-237 is regulated by lin-14 and functions in early developmental timing. Mitchell A. Romens, Benedict J. Kemp, Allison L. Abbott.
A recessive gene controls adaptation to a chemically defined medium in C. elegans. Liusuo Zhang, L. Rene Garcia.
The novel non-coding RNA lep-5 is a heterochronic regulator of male tail tip morphogenesis. Edward Vuong, Karin Kiontke, Antonio Herrera, Douglas Portman, David Fitch.
Development and Evolution: Germline and development and sex determination
Translational control of cyclin B by PUF-8 and GLD-1 is essential for germ cell development. Priti Agarwal, Rana Mainpal, Kuppuswamy Subramaniam.
Investigating the role of WEE-1.3 in C. elegans oocyte maturation. Anna K. Allen, Jessica E. Nesmith, Andy Golden.
Phenotypic differences between deletion alleles of the histone demethylase rbr-2. Stacy Alvares, Ebony Joyner, Shawn Ahmed.
The role of BEC-1 in germ line development in C. elegans. Kristina Ames, Alicia Meléndez.
A comparative evolutionary model for the study of meiotic mechanisms. Joshua Bayes, Abby Dernburg.
Identification and characterization of direct targets of the Caenorhabditis elegans global sexual regulator TRA-1 by chromatin immunoprecipitation. Matthew R. Berkseth, Kohta Ikegami, Jason D. Lieb, David Zarkower.
The eIF4e-binding protein PQN-45 is required for P granule formation and sperm/oocyte switch. Madhu Sharma, Gregory M. Davis, Hyun-Min Kim, Monica P. Colaiacovo, Peter R. Boag.
Implication of microRNA pathway in C. elegans germline biogenesis. Syed Irfan Ahmad Bukhari, Alejandro Vasquez-Rifo, Monique Zetka, Jean-Yves Masson, Martin J. Simard.
Mutations that Interact with the Tip60 HAT Complex Can Suppress SHE-1. Xiangmei Chen, Yiqing Guo, Ronald Ellis.
Loss of ALS-associated protein VAPB/ALS8 increases apoptosis in the germ line. P. Cottee, J. Vibbert, S. Han, M. Miller.
The sexually dimorphic germline stem cell niche. Sarah Crittenden, Ipsita Mohanti, Dana Byrd, Karla Knobel, Judith Kimble.
Caenorhabditis elegans GLB-12 regulates germline apoptosis levels and vulval development. S. De Henau, L. Tilleman, D. Hoogewijs, L. Moens, S. Dewilde, J. R. Vanfleteren, B. P. Braeckman.
PCH-2s Role in Regulating the Synapsis Checkpoint of Meiosis I in Caenorhabditis elegans. Alison J. Deshong, Needhi Bhalla.
Characterization of new sex determination alleles in C. briggsae. Jill A. Dewar, Carlos Carvalho, Paul Stothard, David Pilgrim.
Suppressor of fog-1(q253) rescues fertility in hermaphrodites but not in males. Kristin R. Douglas, Kimberly L. Butnik.
Analysis of HIS-73, a Sperm Specific Histone H3 Variant, Uncovers a Link between Sperm Signaling and TGF-β Signaling. T. Matthew Edwards, Christopher Bean, William G. Kelly.
mel-28 Genetic Interaction Screen Reveals Networks Underlying Germ-line Development in C. elegans. Anita G. Fernandez, Emily Mis, Neha Kaushik, Matthew Fasullo, Fabio Piano.
IFE-1: A Key Regulator of Germ Cell Protein Synthesis. Andrew J. Friday, Jacob Subash, Melissa A. Henderson, Brett D. Keiper.
PUF-8 is an Inhibitor of Germ Line Stem Cell Proliferation. Hilary E. Racher, Laura R. Gauthier, Dave D. Hansen.
The MES proteins cooperate to influence gene expression patterns in the C. elegans germ line. Laura Gaydos, Andreas Rechtsteiner, Coleen Carroll, Wenchao Wang, Susan Strome.
Phenotypic characterization of the tropical hermaphroditic species Caenorhabditis sp. 11. Clotilde Gimond, Nausicaa Poullet, Alessandra Mauri, Nicolas Callemeyn-Torre, Stephanie Grimbert, Paul Vigne, Celine Ferrari, Christian Braendle.
The role of microtubules in regulating dynamic RNP granules in aging or stressed oocytes. Kevin T. Gorman, Tiffany Makowski, Jennifer Schisa.
Loss of a nuclear hormone receptor unravels diet-dependent germline sterility. Xicotencatl Gracida, Christian R. Eckmann.
Translational regulation and the control of meiotic maturation. Caroline Spike, Donna Coetzee, David Greenstein.
A set of spermiogenesis inhibition genes identified by a suppressor screen of spe-27. Gizelle Hacopian, Ubaydah Nasri, Craig LaMunyon.
Identifying mechanisms critical for sperm guidance to oocytes. Hieu D. Hoang, Johnathan W. Edmonds, J. Prasain, Michael A. Miller.
Protein synthesis factor isoforms are selective for mRNAs that promote meiosis and differentiation in germ cells. Melissa A. Henderson, Vince Contreras, Anren Song, Sara Labella, Nadejda Korneeva, J. Kaitlin Morrison, Andrew J. Friday, Monique Zetka, Robert E. Rhoads, Brett D. Keiper.
Elucidating genetic mechanisms by which somatic cAMP signaling regulates MSP-dependent oocyte meiotic maturation. Seongseop Kim, J. Amaranath Govindan, David Greenstein.
VHA-19 is essential for trafficking of RME-2 in Caenorhabditis elegans oocytes and is important for the osmotic integrity of the embryo. Alison J. Knight, Lisa McEwan, Nicholas Johnson, Carolyn Behm.
LET-363/TOR and RSKS-1/S6K promote proper germline development in C. elegans. Dorota Z. Korta, Simon Tuck, E. Jane Albert Hubbard.
Sex-specific regulation of gonadal development in C. elegans. Mary B. Kroetz, W. Clay Spencer, Rebecca D. McWhirter, Matthew R. Berkseth, David M. Miller, III, David Zarkower.
A model of germline population dynamics: in-silico analysis and in-vivo validation. Yaki Setty, Diana Dalfó, Dorota Z. Korta, E. Jane Albert Hubbard, Hillel Kugler.
Comparative functional analysis of hSTIM1 and C. elegans STIM-1. Rashmi P. Kulkarni, Raphael Courjaret, Khaled Machaca.
RFP-1, an E3 ubiquitin ligase, is involved in regulating the proliferation vs. differentiation decision in the C. elegans germline. Lindsay Leahul, Brendan Bakos, Dave Hansen.
Development of a C. elegans Spermiogenesis and Sperm Function Protein Interaction Network. Matthew R. Marcello, Marina Druzhinina, Gunasekaran Singaravelu, Andrew Singson.
Insulin, Notch, Cyclins and the Regulation of Germline Development. David Michaelson, E. Jane Albert Hubbard.
Role of METT-10, a putative methyltransferase, in the proliferation vs meiosis decision. Ariz Mohd, Maia Dorsett, Tim Schedl.
FOG-1 activates fog-3 expression. Dyan Morgan, Johan Jeong, Daniel Noble, Judith Kimble.
RNA localization in the germline. Alexandre Paix, Geraldine Seydoux.
Robustness and evolvability of sex determination pathway. Manish Parihar, Andre Pires da Silva.
RNP granules: insights into their regulation and function. Joseph R. Patterson, Megan P. Wood, Jennifer A. Schisa.
A novel role of the RNA helicase VBH-1 during stress. Daniel Paz-Gomez, Rosa E. Navarro.
Evolution and phenotypic plasticity of the germline and reproductive system in Caenorhabditis nematodes. Nausicaa Poullet, Christian Braendle.
Maintenance of adult proliferative germ cells. Zhao Qin, E. Jane Albert Hubbard.
Mapping and Characterization of Caenorhabditis elegans Mutant Defective in Sperm Function. Sina Rahimi, Gunasekaran Singarevelu, Andrew Singson.
glp-4 encodes the valyl amino-acyl tRNA synthetase VARS-2. Suchita Rastogi, Ben Borgo, Paul Fox, Nannette Pazdernik, Elaine Mardis, Yuji Kohara, Jim Havranek, Tim Schedl.
A role for cardiolipin in the gonad development of Caenorhabditis elegans. Taro Sakamoto, Nagaharu Yokomori, Yukae Otomo, Motoki Ohno, Takao Ioue, Hiroyuki Arai, Yasuhito Nakagawa.
The DEAD box RNA helicase Cr-VBH-1 is a constitutively P granule component in C. remanei germ cells and plays an important role on its germline function. Laura Silvia Salinas Velázquez, Ari Franco-Cea, Laura Lascarez-Lagunas, Ernesto Maldonado, Rosa E. Navarro.
The tumour suppressor ING-3 regulates the DNA damage-induce apoptosis pathway in C. elegans. Sitar Shah, Jingjing Luo, JB Rattner, Karl Riabowol, Paul Mains.
SPE-44 functions as an early transcription factor in spermatogenesis. Madhura Kulkarni, Katherine E. Guevel, Diane C. Shakes, Harold E. Smith.
Regulation of Hermaphrodite Development by the F-box Protein SHE-1. Y. Shen, Ronald E. Ellis.
Two likely GLP-1/Notch targets are essential for germline stem sell maintenance in both larvae and adults. Aaron M. Kershner, Heaji J. Shin, Judith Kimble.
Regulation of the trafficking of TRP-3 channel by a novel protein during spermiogenesis in Caenorhabditis elegans. Gunasekaran Singaravelu, Indrani Chatterjee, Sina Rahimi, Marina Druzhinina, Andrew Singson.
Chemically reprogramming the adult sperm/oocyte fate decision. Elena P. Sorokin, Clinton T. Morgan, Judith Kimble.
A peroxiredoxin antioxidant enzyme regulates the timing of hermaphrodite spermatogenesis. Joanne Stamford, Christian Eckmann, Elizabeth Veal.
A sperm competition mutant with defects in sperm motility. Daniela Chavez, Gillian Stanfield.
Sperm-egg fusion generates a biphasic traveling calcium wave in C. elegans. J. Takayama, S. Onami.
The conserved PAM-1 aminopeptidase somatically regulates pachytene progression. Chris Trzepacz, Craig Mello.
Regulation of RAS/MAPK signaling by PUF-8 and GAP-3 is essential for meiotic progression. Samir Vaid, Mohd Ariz, Kuppuswamy Subramaniam.
Detachment of the pharynx in lim-7(tm674) mutants occurs embryonically. Laura G. Vallier.
Centriole elimination during C. elegans oogenesis. Lukas von Tobel, Tamara Mikeladze-Dvali, Pierre Gönczy.
Identifying TEG-1 interacting proteins that are involved in germline development. Chris Wang, Dave Hansen.
The PP2A phosphatase subunit PPTR-1 is required to stabilize embryonic P granules during mitosis. Jennifer T. Wang, Christopher M. Gallo, Geraldine Seydoux.
Assembly of a Membrane-associated Complex Required for the Oocyte-to-embryo Transition. Yuemeng Wang, Geraldine Seydoux.
The role of the protein kinase CHK-1 in early germ line development in C. elegans. Ashley B. Williams, W. Matthew Michael.
GLD-1 binding marks specific mRNA targets for accumulation in oocytes. Claudia Scheckel, Dimos Gaidatzis, Jane E. Wright, Rafal Ciosk.
Regulation of P granule stability via PGL proteins. M. Yonetani, M. Hanazawa, A. Sugimoto.
Exploring the role of RNP granules in regulating RNA stability. Mark T. Zeigler, Breanna Rice, Jennifer Schisa.
Development and Evolution: Evolution
N2-specific differences in behavior, growth, and physiology are explained by a laboratory-derived allele of npr-1. Erik C. Andersen, Raj Ghosh, Josh S. Bloom, Justin P. Gerke, Leonid Kruglyak.
Exploring the mutational landscape of Caenorhabditis. Dee Denver, Larry Wilhelm, Peter Dolan, Dana Howe, K. Gafner, Charles Baer.
Proximate and ultimate cumulative effects of temperature on spontaneous mutation in C. briggsae and C. elegans. Dejerianne Ostrow, Suzanna Lewis, Chikako Matsuba, Matthew Salomon, Laurence Sylvestre, Kerry Regan, Brandon Tabman, Ambuj Upadhyay, Charles F. Baer.
Ray Pattern Variation in C. elegans: Mapping a Major-Effect QTL on LGV. Scott E. Baird, Daniel Bailey.
A Bias Caused by Ectopic Development Creates Sexually Dimorphic Sperm In Nematodes. Christopher C. Baldi, Jeffrey Viviano, Ronald E. Ellis.
Cryptic evolution of transcriptional regulation through changes in cis and trans. Antoine Barriere, Kacy Gordon, Ilya Ruvinsky.
Evolution in viral sensitivity to the Orsay virus in natural C. elegans isolates. Tony Bélicard, Marie-Anne Félix.
Stochastic influences on physiology and the outcomes of mutation in C. elegans. Maria O. Casanueva, Ben Lehner.
Removal of selection pressure leads to convergent male behavior in Caenorhabditis. Audrey S. Chang, Matthew Rockman.
Adaptation and effective recombination in C. elegans populations with standing variation. I. Chelo, H. Teotónio.
Identification of ascr#1 as the female sex pheromone in the free-living nematode Panagrellus redivivus. A. Choe, A. T. Dossey, T. Chuman, R. Ajredini, D. Kogan, H. Alborn, F. Kaplan, H. Von Reuss, F. Schroeder, A. S. Edison, P. W. Sternberg.
The evolution and genetics of speciation between C. briggsae and C. sp. 9. Asher D. Cutter, Joanna L. Kozlowska.
Natural ecology of C. elegans in Germany. Philipp Dirksen, Fabian Peters, Wei Chen, Carola Petersen, Katja Dierking, Hinrich Schulenburg.
Ecology of Caenorhabditis: sharing of natural habitats by different Caenorhabditis species. Marie-Anne Félix, Christian Braendle.
Comparison of early embryogenesis in eight species of Protorhabditis. Hélčne Fradin, Karin Kiontke, David H. A. Fitch, Fabio Piano.
Functional genomics of two Antarctic nematodes, Panagrolaimus davidi and Plectus murrayi. Hiroshi Kagoshima, Yuji Kohara.
Natural variation of gonad independent vulva induction among Pristionchus pacificus isolates. Simone Kienle, Ralf J. Sommer.
DPY-1 plays a conserved role in nematode cuticle formation. Sandrine Jacob, Christian Olendrowitz, Delphine Bernard, Joachim M. Muriel, Charlotte Kenning, Olivier Poupel, Jan Hagermann, Danny Tuckwell, Ralf Sommer, Stefan Eimer, Bernard Lakowski.
Spontaneous and UV-induced mutations in a small region of the C. elegans genome, the ben-1 locus. Cecilia C. Mello, Andrew Fire.
Comparative proteome analysis of Caenorhabditis elegans cultured at 2 different temperatures20°C and 25°C. K. Monobe, Y. Ishido, A. Terasawa, Y. Tohsato, T. Hayano, M. Ito.
Variations in sensitivity to external RNA interference in the Caenorhabditis genus. Isabelle Nuez, Marie-Anne Félix.
Effect of Mutation Accumulation Environment on Environmental Variance in Fitness in Caenorhabitis. Rayshard Rogers, Charles Baer.
Back to Nature: Defining the Microbiota of Wild C. elegans. Buck S. Samuel, Christian Braendle, Marie-Anne Félix, Gary Ruvkun.
Experimental test of the consequences of host-parasite coevolution. Hinrich Schulenburg, Leila El Masri, David Laehnemann, Patrick Guenther, Nicolaas K. Michiels.
Evolution of Sex-biased Expression in the Caenorhabditis genus. Cristel G. Thomas, Renhua Li, Ian Korf, Harold E. Smith, Brian Oliver, Eric S. Haag.
Quantitative Proteomic Analysis of 3 Developmental Stages of Caenorhabditis briggsae by Using 2D DIGE and iTRAQ. A. Terasawa, Y. Tohsato, Y. Ishido, T. Hayano, M. Ito.
Constructing and screening an RNAi Library in C.briggsae reveals evolution in phylogenetically young proteins and transcription factors. Adrian Verster, Arun Ramani, Sheldon Mckay, Felix Marie-Anne, Andew Fraser.
Independent evolution of PP1 phosphatases for regulation of diverse sperm motility structures. Jui-ching Wu, Aiza Go, Susan Mirosoian, Mark Samson, Thais Cintra, Tammy Wu, Margaret Jow, Rodrigo Estrada, Eric Routman, Diana Chu.
Establishing C. briggsae as a Model System for Speciation Research. Zhongying Zhao, Stephane Flibotte, Donald Moerman, Robert Waterston.
Gene Regulation and Genomics: Gene expression
Screening for novel regulators of rnt-1 in stress response. Soungyub Ahn, Kiho Lee, Junho Lee.
Identifying genes that interact with APL-1, a Protein Related to Human Amyloid Precursor Protein. Adanna G. Alexander, Chris Li.
Microtubules and fertilization: The MEI-1/katanin mediated cytoskeletal transition from meiosis to mitosis in the developing embryo. Sarah M. Beard, Paul Mains.
Identification of transcription start sites and novel transcripts in C. elegans. Ron Chen, Thomas Down, Julie Ahringer.
Cis-regulating network in the ALA neuron. Elly S. Chow, Cheryl Van Buskirk, Paul Sternberg.
Dissecting the role of ncbp-1/ncbp-2 in determining ray patterns in C. elegans males. JHT Wong, KL Chow.
The nature of tbx-2 expression pattern in C. elegans male tail. KK Ip, KL Chow.
Comparative genomics reveals novel regulatory mechanism for the transcription factor RFX/DAF-19 in C. elegans. Jeffrey S. C. Chu, Maja Tarailo-Graovac, Jun Wang, Bora Uyar, Domena Tu, Joanne Trinh, Bob Johnsen, David Baillie, Nansheng Chen.
The dynamics of gene expression in early larval development. Shu Yi Chua, Hee Sun Shin, Jean Thierry-Mieg, Danielle Thierry-Mieg, David L. Baillie.
Regulation of intestinal fasting induced transcription of nhr-206 is DAF-16/FOXO dependent. Ahmed Chughtai, Jan Novotny, Frantisek Behensky, Zdenek Kostrouch, Marta Kostrouchova.
In vivo Regulation of the Alternative Splicing of the Pro- and Anti-Apoptotic Gene ced-4. Anna Corrionero, Bob Horvitz.
Regulation of X chromosome transcription in Caenorhabditis species. Sarah Albritton, Sevinc Ercan.
Chromosome-wide gene regulation and higher-order chromosome structure in C. elegans dosage compensation. C. A. Fassio, E. Crane, A. Michel, S. Uzawa, B. J. Meyer.
HLH-17 affects dopamine signaling in C. elegans through the DOP-1, DOP-2 and DOP-3 receptors. Chaquettea M. Felton, Casonya Johnson.
rsr-2, the ortholog of the human spliceosome component SRm300/SRRM2, regulates diverse developmental processes including germline sex determination. Laura Fontrodona, Tomás Morán, Montserrat Porta-de-la-Riva, Mňnica Díaz, David Aristizábal, Alberto Villanueva, Simó Schwartz Jr., Julián Cerón.
The identification of the functional components of the male-specific CEM neurons. Lan Fu, Gus C. M. Chan, King L. Chow.
Transcriptional regulation of pharyngeal gland sub-type expressed genes. Vikas Ghai, Jeb Gaudet.
Characterization of specific gene programs regulated by Mediator subunit CDK-8. Jennifer M. Grants, Stefan Taubert.
A new model of C. elegans embryogenesis with cell contacts and spatio-temporal gene expressions. Johan Henriksson, Jürgen Hench, Martin Lüppert, Akram Abou-Zied, David Baillie, Thomas R. Bürglin.
Microarray analysis on laser-dissected tail tips identifies genes regulated by dmd-3 during male tail tip morphogenesis. R. Antonio Herrera, Karin Kiontke, D. Adam Mason, Ji-Sup Yang, David H. A. Fitch.
Operon transcriptional complexity: dissection via recombineered fosmid-based reporters. Nisha Hirani, Stephen Sturzenbaum, Colin Dolphin.
Temporal control of organogenesis by PHA-4/FoxA. Hui-Ting Hsu, Susan Mango.
RNA polymerase III transcribes a defined subset of tRNAs and snoRNAs at the nuclear pore in C. elegans. Kohta Ikegami, Jason Lieb.
Possible regulation of bed-3 by blmp-1. Takao Inoue.
Searching for transcriptional regulators of C. elegans proteasome subunits. CongYu Jin, YueHong Yang, Akihiro Mori, Yuji Kohara, Xuan Li, Johan Dethlefsen, Johan Henriksson, Keith Blackwell, Thomas Bürglin, Carina I. Holmberg.
The homeobox transcription factors, CEH-14 and TTX-1, regulate expression of gcy-8 and gcy-18 in C. elegans. Hiroshi Kagoshima, Yuji Kohara.
Novel fat-reducing plant extracts as therapeutics in the treatment of obesity using a C. elegans model. Shail Kaushik, Harsh Bais.
The affects of DNA sequence on chromatin architecture and gene expression. Colton E. Kempton, Elliot Winters, Benjamin Jorgensen, Steven M. Johnson.
The overlapping roles of hlh-1 and unc-120 in bodywall muscle differentiation. Steven G. Kuntz, Brian Williams, Paul Sternberg, Barbara Wold.
FOX-1 family and UNC-75 regulate neuron-specific alternative splicing of the unc-32 gene. Hidehito Kuroyanagi, Masatoshi Hagiwara.
SMG-1 may possess dual mRNA surveillance functions . Luciana Leopold, Matt Eckler, Yan Liu, Channing Der, David Reiner, Shawn Ahmed.
Regulation of calreticulin gene expression by sumoylation in C. elegance. Yun-Ki Lim, Sunkyung Lee, Joohong Ahnn, Do Han Kim.
Identification of transcription factors regulating lin-39 expression. Wan-Ju Liu, David Eisenmann.
Analysis of cell fate from single-cell gene expression profiles in C. elegans. Xiao Liu, Sarah Aerni, Fuhui Long, Hanchuan Peng, John Murray, Serafim Batzoglou, Robert Waterston, Gene Myers, Stuart Kim.
Identification of evolutionary conserved regulators of dietary restriction using the "Ortho2ExpressMatrix". Andreas Ludewig, Thomas Meinel, Frank Doering.
In vivo analysis of splicing factor genes in regulating alternative splicing in C. elegans. Yanling Teng, Xiaoyang Gao, Long Ma.
Analysis of temporal expression data of C.elegans early embryo. T. Maeshiro, S. Nakayama, K. Monobe, M. Ito.
Structure-function analysis of MDT-15, a conserved transcriptional co-regulator required for metabolic homeostasis. Allan Mah, Ada Kwong, Stefan Taubert.
A 3UTR clone library of the nematode C. elegans: a resource for 3UTR biology. M. Mangone, J. M. Lucas, M. R. Gutwein, D. Mecenas, K. C. Gunsalus, F. Piano.
Factors Affecting the Mean, Variance and Predictive Power of a Lifespan-Predicting Biomarker. Alexander R. Mendenhall, Pat Tedesco, James R. Cypser, Larry Taylor, Anita Lowe, Roger Brent, Thomas E. Johnson.
GEI-8 is a transcription co-repressor orthologous to NCoR/SMRT with developmental functions in C. elegans. Pavol Mikolas, Frantisek Behensky, Vladimir Saudek, Michael Krause, Zdenek Kostrouch, Marta Kostrouchova.
Biochemical characterization of canonical and variant C.elegans nucleosomes. Ahmad N. Nabhan, Margaret Jow, Diana Chu, Geeta Narlikar.
AlkB8 (C14B1.10) regulates metabolism in C. elegans. Johana Nakielna, Petr Yilma, Vladimir Saudek, Marta Kostrouchova, Zdenek Kostrouch.
Defining target genes of the transcriptional repressor protein CTBP-1. Hannah R. Nicholas, Surya Setiyaputra, Melinda S.-Y. Tan, Chu-Kong Liu, Aaron Lun, Sashi Kant, Merlin Crossley, Joel Mackay.
Characterization of the aminophospholipid translocase TAT-1 and phosphatidylserine asymmetry in plasma membrane. Y. Niu, Q. Yuan, N. Xia, D. Xue.
Single-blastomere transcriptome profiling reveals asymmetric segregation of maternal transcripts in the first embryonic division. Erin A. Osborne, Jason D. Lieb.
Global and phenotype-specific suppressors of LIN-35/pRb synthetic phenotypes. Stanley R. Polley, David Fay.
Functional characterization of swsn-2.1, a SWI/SNF component and genetic interactor of lin-35 Retinoblastoma. Iris Ertl, Montserrat Porta-de-la-Riva, Laura Fontrodona, Eva Gómez-Orte, Lucía Suárez-López, Verónica Dávalos, Simó Schwartz Jr., Juan Cabello, Julián Cerón.
Oxygen-sensitive gene expression in C. elegans. Dingxia Feng, Jo A. Powell-Coffman.
C. elegans TBX-2 is a SUMOylation dependent transcriptional repressor. Lynn Clary, Tom Ronan, Peter Okkema.
Slimming Nematodes with Herbal Medicine: From pseudo-science to reality. Soudabeh Sahmeddini, Peter Hylands, Stephen Sturzenbaum.
Regulation of gene expression by DBL-1/BMP. Jianghua Yin, Sushma Teegala, Edlira Yzeiraj, Cathy Savage-Dunn.
Comparison of Dosage Compensation Between Caenorhabditis briggsae and Caenorhabditis elegans. Caitlin M. Schartner, Te-Wen Lo, Barbara J. Meyer.
Carnosinase 1 (PES-9) and Carnosinase 2 (Y71H2AM.11) - two conserved dipeptidases are involved in regulation of embryonic development in C. elegans. Katerina Sebkova, Petr Yilma, David Kostrouch, Zdenek Kostrouch, Marta Kostrouchova.
Characterizing the paternal RNA contribution of C. elegans sperm. M. Shorrock, T. Wu, D. S. Chu.
Characterization of HRG-7, a novel protease involved in C. elegans heme homeostasis. Jason Sinclair, Iqbal Hamza.
Transcriptional regulation of ciliary genes in C. elegans. J. Burghoorn, BP Piasecki, KE Jeppsson, F. Crona, S. Sahlin, P. Phirke, P. Swoboda.
Asymmetric regulation of the homeobox gene ceh-5 in early embryogenesis of C. elegans. Lois Tang, Konstantin Cesnulevicius, Jürgen Hench, Daria Shlyueva, Akram Abou-Zied, Thomas Bürglin.
An integrated view of the organization of transcription factor binding sites in the C. elegans genome. Florian Wagner, Itai Yanai.
scla-1 Encodes a Nonreceptor Tyrosine Kinase Required for Antipsychotic Drug-induced Developmental Delay and Lethality in C. elegans. X. Wang, L. M. Hao, B. M. Cohen, E. A. Buttner.
Linking dosage compensation complex binding to chromosome-wide gene regulation in C. elegans. Bayly Wheeler, Barbara Meyer.
The REF-1 Protein, HLH-29, Functions in the Somatic Gonad of Wild-Type C. elegans. Ana M. White, Casonya Johnson.
Promoter Analysis of the GATA type transcription factor elt-2. Tobias Wiesenfahrt, Janette Berg, James McGhee.
Identification and characterization of protein phosphatases that regulate TGFβ signaling in C. elegan. S. Xiong, C. Savage-Dunn.
Repression of transgene expression by the Q/P-rich nuclear protein PQE-1. Koji Yamada, Jun-ichi Tsuchiya, Yuichi Iino.
Identification of critical neurons for APL-1 expression in C. elegans. Pei Zhao, Collin Ewald, Chris Li.
Identifying Regulatory Elements Controlling Spatial And Temporal Expression of hlh-29 in C. elegans. Huihui Zhu, Casonya Johnson.
Gene Regulation and Genomics: RNA interference and small RNAs
Multi-platform sequencing identifies novel mirtron with an embryonic lethal phenotype in Caenorhabditis elegans. Rina Ahmed, Funda Sar, Zisong Chang, Kristin Gunsalus, Erik Miska, Christoph Dieterich.
RNA-binding Protein GLD-1 Genetically Interacts with Multiple miRNA Pathways in C. elegans. Alper Akay, Ashley Craig, Nicolas Lehrbach, Gyorgy Hutvagner, Eric Miska, Anton Gartner.
Rab-7 can modulate microRNA activity in C. elegans. Zhiji Ren, Victor R. Ambros.
RNAi-promoting Zinc Finger Protein, ZFP-1, is an essential factor required for chromatin integrity in C. elegans. Daphne Anastasiades, Germano Cecere, Morten Jensen, Jason Lieb, Alla Grishok.
In situ hybridization analysis of let-7 microRNA. Yoshiki Andachi, Yuji Kohara.
rde-4 is epistatic to rde-4. Stephen A. Banse, Craig P. Hunter.
A function for mir-34 in gonad morphogenesis. Samantha Burke, Molly Hammell, Victor Ambros.
A Conserved Motif Affecting Nucleosome Occupancy is Required for 21U-RNA Production in C. elegans. Germano Cecere, Grace Zheng, Katherine Klymko, Andres Mansisidor, Alla Grishok.
RACK-1 acts in let-7-mediated heterochronic development of Caenorhabditis elegans. Shih-Peng Chan, Frank Slack.
A Genome-wide analysis of genetic interactions in early embryogenesis in C. elegans. P. G. Cipriani, E. Munarriz, A. White, HL. Kao, J. Young, K. Erickson, S. Guzman, J. Lucas, K. C. Gunsalus, F. Piano.
Yeast One-Hybrid Screen to Identify Factors Required for piRNA Biogenesis in C. elegans. Amanda Day, John Kim.
Cel-bantam miRNA family regulates TGF-β Sma/Mab pathway. María Pilar de Lucas, Encarnación Lozano.
Germline expression, inheritance, and genomic characteristics of Caenorhabditis elegans 21U-RNAs. Mallory Freeberg, John Kim.
Single-worm RNA-seq as a tool for following epigenetic silencing. Weifeng Gu, Ahmed Ahmed Elewa, Craig Mello.
Nuclear RNAi mediates off-target gene silencing. Shouhong Guang, Kirk Burkhart, Virginia Lamb, Scott Kennedy.
Casein kinase 2 (KIN-3/KIN-10) regulates microRNA activity in C. elegans. Ting Han, Vishal Khivansara, James Moresco, John Yates, John Kim.
Regulation of mir-34 expression by insulin signaling pathway in C. elegans. M. Isik, E. Berezikov.
miRNA regulation of stress responses. Konstantinos Kagias, Roger Pocock.
Variable Replication of a Flock House Virus Transgene in Caenorhabditis Natural Isolates. EE Large, G. Broitman-Maduro, SW Ding, M. Maduro.
Genetic identification of post-transcriptional modulators of microRNAs. Katherine McJunkin, Victor Ambros.
Analysis of miR-35 stablity at the embryo-larval transition in C. elegans. Kenneth J. Murfitt, Javier Armisen-Garrido, Nicholas J. Lehrbach, Eric A. Miska.
Characterization of Transposon Silencing Pathways. Carolyn M. Phillips, Gary B. Ruvkun.
TDP-1, the C. elegans ortholog of ALS-associated protein TDP-43, modulates RNA editing and RNAi. Tassa K. Saldi, Christine M. Roberts, Peter E. A. Ash, Leonard Petrucelli, Christopher D. Link.
RNAi screen to identify new genes and pathways regulating PKD-2 ciliary localization and function. Bahareh Shanehsaz, Cory Patrick, Juan Wang, Maureen Barr.
The mevalonate pathway has a role in microRNA repression of target genes. Zhen Shi, Gary Ruvkun.
Sensitized Backgrounds Reveal Critical Roles for microRNA Families. Elizabeth J. Thatcher, Victor Ambros.
Piwi proteins and piRNAs: targets, targeting requirements and pathway analysis. E.-M. Weick, L. D. Goldstein, M. P. Bagijn, A. Sapetschnig, E. A. Miska.
Repression of germline RNAi pathways in somatic cells by multiple synMuv B chromatin complexes. Xiaoyun Wu, Zhen Shi, Mingxue Cui, Min Han, Gary Ruvkun.
The RDE-10/RDE-11 complex is required for RNAi-induced mRNA turnover in C. elegans. Huan Yang, Ho Yi Mak.
A Role for Systemic RNAi in antiviral defense in C. elegans. Jing Zhong, Gao Zhihuan, Morris Maduro, Ding Shou-wei.
An integrated approach for in vivo miRNA regulation studies in C. elegans. Ilyass Zniber, Marie Bothorel, Léo Guignard, Denis Dupuy.
Gene Regulation and Genomics: Genomics
Towards a unique gateway for predicting genetic interactions in C. elegans. Benjamin Boucher, Anna Y. Lee, Michael Hallett, Sarah Jenna.
Essentially C. elegans: A step towards defining the Essentialome of the Worm. Jeffrey S. C. Chu, Bob Johnsen, Domena Tu, Steven Jones, Marco Marra, David Baillie, Ann Rose.
WormBase Gene Sets and Sequence Curation -. Paul Davis, Tamberlyn Bieri, Kevin Howe, William Nash, Philip Ozersky, Gary Williams, John Spieth, The WormBase Consortium.
Building better gene and orthology predictions across ten Caenorhabditis genomes. Olivia Gardner, Ana Rodrigues, Yufeng Zhai, Gerard Manning.
Investigating the roles of a worm HP1 homolog during embryogenesis. Jacob Garrigues, Thea Egelhofer, Susan Strome.
Identification of new DNA targets of nuclear envelope proteins in C. elegans using the DamID technique. Cristina Gonzalez-Aguilera, Peter Askjaer.
Links between histone modifications and splicing. Moritz S. Herrmann, Paulina Kolasinska-Zwierz, Julie Ahringer.
Quantitative epistasis map of genes regulating sex ratio. Marta K. Labocha, Wenshan Luo, Boanerges Aleman-Meza, Weiwei Zhong.
A transcription factor specific RNAi screen to identify regulators of intestinal gene expression. Lesley T. MacNeil, H. Efsun Arda, A. J. Marian Walhout.
Characterization of the Transcriptome in L1 Arrest and Recovery with High Throughput Sequencing. Colin Maxwell, Igor Antoshechkin, Nicole Kurhanewicz, Jason Belsky, Ryan Baugh.
Analysis of mutation patterns in C. elegans strains with DNA repair deficiencies. Bettina Meier, Peter Campbell, Anton Gartner.
Estimation of gene regulatory networks of C.elegans early embryo. A. Okano, K. Monobe, S. Nakayama, M. Ito, T. Maeshiro.
Uncovering cryptic genetic variation for C. elegans embryogenesis. Annalise Paaby, Amelia White, Kris Gunsalus, Fabio Piano, Matt Rockman.
Unique mono-nucleosome occupancy on the Caenorhabditis sex chromosome. Christine G. Preston, Yvonne Fondufe-Mittendorf, Jonathan Widom, Barbara J. Meyer.
Whole-genome analysis of alternative splicing in C. elegans. Arun Ramani, John Calarco, Qun Pan, Sepand Mavandadi, Ying Wang, Andrew Nelson, Leo Lee, Quaid Morris, Benjamin Blencowe, Mei Zhen, Andrew Fraser.
The C. elegans transcriptome. Valerie Reinke, Brent Ewing, Mark Gerstein, Phil Green, S. Henz, Amber High, LaDeana Hillier, Masaomi Kato, J. Leng, Michael MacCoss, Gennifer Merrihew, David M. Miller, III, Gunnar Ratsch, Rebecca Robilotto, Frank J. Slack, W. Clay Spencer, Pnina Strasbourger, Owen Thompson, Guilin Wang, Georg Zeller, Robert H. Waterston.
Evolution of a Transcriptional Program: Tracking the Heat Shock Response Across Phyla. Ana P. Rodrigues, Gerard Manning.
Wormfood Genomics: E. Coli Determinants of C. elegans Fitness. Buck S. Samuel, Tim Durfee, Holli Rowedder, Chris Carr, Justine Melo, Jeremy Glasner, Sean Sykes, Sarah Young, Carsten Russ, Guy Plunkett, Chad Nusbaum, Gary Ruvkun.
An alternative analysis pipeline for mutation identification by next-generation sequencing. Harold E. Smith, Michael W. Krause.
High Occupancy Target (HOT) regions in C. elegans. Eric Van Nostrand, Stuart Kim, C. elegans modENCODE consortium.
Loss-of-Function genomic variations in wild Caenorhabditis elegans. Ismael A. Vergara, Maja Tarailo-Graovac, Jun Wang, Nansheng Chen.
A systematic examination of the effects of natural variation on perturbed phenotypes in Caenorhabditis Elegans. Victoria Vu, Arun Ramani, Tungalag Chuluunbaatar, Hong Na, Andrew Fraser.
Cell Biology: Cell polarity and the intracellular trafficking
Tissue-specific identification of polarity protein complexes. Selma Waaijers, Javier Muńoz, Albert Heck, Mike Boxem.
Sperm Mitochondria are Associated with Ubiquitinated Vesicles After Fertilization. Connie Hajjar, Andy Golden, Lynn Boyd.
Isolation of novel molecules that regulate specialized ciliary morphologies. Andrea Brear, Alexander van der Linden, Piali Sengupta.
Identification of novel proteins involved in the regulation of IFT. Joost Broekhuis, Weng Yee Leong, Gert Jansen.
The GMAP210 homologue SQL-1 modulates Intraflagellar Transport in C. elegans. Suzanne Rademakers, Joost Broekhuis, Martijn Dekkers, Jan Burghoorn, Gert Jansen.
EXC Proteins Regulate Early Endosome Trafficking to Maintain Apical Surface in Narrow Tubules of C. elegans. Brendan Mattingly, Kelly Grussendorf, Elinor Brown, Matthew Buechner.
Identification of RhoGEFs that activate CDC-42 during radial polarization of the early C. elegans embryo. Emily Chan, Jeremy Nance.
Functional Analysis of the AP-3 Clathrin-associated Adaptor Complex in Caenorhabditis elegans. Carlos Chih-Hsiung Chen, Anbing Shi, Donglei Zhang, Zhiyong Bai, Peter J. Schweinsberg, Lucy Mingchih Lee, Barth D. Grant, Christopher Rongo.
JIP3/UNC-16 has an UNC-101 dependent role in synaptic vesicle biogenesis. Bikash C. Choudhary, Jitendra Kumar, Takashi Fukuzono, Li Chun, Kunihiro Matsumoto, Naoki Hisamoto, Sandhya P. Koushika.
The Role of Intracellular Trafficking in Modulating Ciliary Structure and Function in C. elegans. David B. Doroquez, Anique Olivier-Mason, Ali Sarkeshik, John R. Yates III, Piali Sengupta.
Isolation and Characterization of tat-1 suppressors. Xin Li, Hongwei Du, Baohui Chen, Xiaochen Wang.
qx42 affects lysosome function and embryonic development in C. elegans. Bin Liu, Hongwei Du, Xiaochen Wang.
An in vivo screen of localization and trafficking regulators of LET-23 EGFR. Juan M. Escobar Restrepo, Christina J. Herrmann, Langouet M., Hajnal A.
PAR proteins regulate the localization of LET-99 during asymmetric division. Jui-Ching Wu, Eugenel B. Espiritu, Lesilee S. Rose.
Intracellular trafficking of the type I and type II TGFβ receptors, SMA-6 and DAF-4, in C. elegans. Ryan Gleason, Adenrele Akintobi, Barth Grant, Richard Padgett.
The EXC-1 GTPase Is Required for Maintenance of Tubule Shape in the Excretory Canals. Kelly Grussendorf, Amanda Riss, Matthew Buechner.
Molecular characterization of TGF-β regulation by multiple intracellular vesicle trafficking processes in C. elegans. Katherine Beifuss, Tina Gumienny.
Regulation of the RAB-2 GTPase involved in Dense-Core Vesicle Maturation. Mandy Hannemann, Stefan Eimer.
Investigating the function of the GLO-1 Rab GTPase in lysosome-related organelle biogenesis. Hannah Somhegyi, Thomas Curtin, Brian King, Travis Walton, Greg J. Hermann.
GLO-2 is a nematode specific factor functioning in gut granule biogenesis. Daniel Saxton, Emily Scavarda, Allison M. Weis, Becca Salesky, Laura Thomas, Kaila Warren, Alec Barret, Greg J. Hermann.
Zygotic expression of par-1 suggests multiple functions. Daryl D. Hurd.
Intracellular PLA1 and acyltransferase, which are involved in C. elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol. Rieko Imae, Takao Inoue, Masako Kimura, Eriko Kage-Nakadai, Shohei Mitani, Hiroyuki Arai.
Possible role of pak-1/Pak and ced-10/Rac in Wnt/Ror signaling. Kah Yee Goh, Natalie Ng, Thilo Hagen, Takao Inoue.
Characterization of the exocyst in C. elegans. Yaming Jiu, Jussi Jäntti.
Physiological roles of ESCRT complexes in Caenorhabditis elegans. Dong-Wan Kim, Hyun Sung, Donghyuk Shin, Haihong Shen, Joohong Ahnn, Sun-Kyung Lee, Sangho Lee.
Centrosome centration is driven by dynein-dependent movement of intracellular organelles along astral microtubules in C. elegans early embryos. Kenji Kimura, Akatsuki Kimura.
Tubulin polyglutamylation in the sensory cilia is flexibly regulated in response to the environmental stresses. Y. Kimura, O. I. Kaplan, S. Hameed, H. Kunitomo, Y. Iino, O. E. Blacque, M. Setou.
Centrosome positioning and the establishment of the anterior-posterior axis in the one-cell embryo. Zachary Klock, Jessica Meeker, Margaret Williams, Liza Agayeva, George Pellegrino, Eva Jaeger, Rebecca Lyczak.
Identifying mechanisms of contact-mediated cell polarization. Diana Klompstra, Dorian Anderson, Jeremy Nance.
Dissection of the LATS kinase pathway in C. elegans. Hanee Lee, Junsu Kang, Junho Lee.
SUMOylation of ARL-13 regulates ciliogenesis and cilia sensory function. Yujie Li, Jinghua Hu.
Coordination of Arls in cilia. Yujie Li, Qing Wei, Yuxia Zhang, Jinghua Hu.
Tracing Endocytosis in the Nematode Gut. Willisa Liou, Barth Grant, Ayesha Hossain, David Hall.
Identification of novel factors antagonizing endocytic organelle fusion in C. elegans. Kai Liu, Zhiyang Gao, Xiaojuan Sun.
Identification of a New Gene Required for the Proper Localization of PKD-2 to Cilia. Julie Maguire, Maureen Barr.
Putative De-ubiquitylating Enzymes MATH-33 and USP-47 are Required for Polarity Establishment in C. elegans. Richard J. McCloskey, Kenneth Kemphues.
FGF signaling cooperates with WNT signaling in C. elegans vulval cell lineage polarity. Paul Minor, Anand Asthagiri, Paul Sternberg.
C.elegans rootletin homolog, che-10, is required for intraflagellar transport and cilia maintenance. Swetha Mohan, Michel Leroux.
Immunoglobulin domain containing isoforms of UNC-89 (obscurin) are required for myofilament organization and calcium signaling in Caenorhabditis elegans. Patrick Spooner, M. Berenice Duran, Jennifer Bonner, Guy Benian, Kenneth Norman.
Role of the cullin CUL-5 in the regulation of polarity and asymmetric division. Anne Pacquelet, Grégoire Michaux.
Molecular and genetic characterization of suppressor of bec-1 lethality (sub) mutants. Nicholas J. Palmisano, Alicia Meléndez.
Arp2/3 dependent branched actin regulates intracellular trafficking to maintain apical junctions. Falshruti B. Patel, Yelena Bernadskaya, Martha Soto.
Identification and characterization of novel Wnt signaling pathway components. Woon Cheng Poh, Yanqing Shen, Takao Inoue.
Endocytic regulation of LET-23 EGFR signaling during vulva induction. Olga Skorobogata, Christian E. Rocheleau.
Novel players of cell polarity and asymmetric cell division in C. elegans identified through analysis of a polarity genetic network. Josana Rodriguez, Bruno Fievet, Julie Ahringer.
Characterizing the adrenomedullin homologue in C. elegans. Beatriz Sáenz-Narciso, Eva Gómez-Orte, Alfredo Martínez, Juan Cabello.
Dynein-dependent microtubule sliding is not sufficient for anaphase spindle-pulling force in the C. elegans embryo. Eva Gusnowksi, Martin Srayko.
Spindle asymmetry produced by Wnt signaling regulates asymmetric nuclear localization of β-catenin. Kenji Sugioka, Kota Mizumoto, Hitoshi Sawa.
Identification of SORF-1 (suppressor of organelle fusion) as a negative regulator of endocytic organelle fusion in C.elegans. Xiaojuan Sun, Zhiyang Gao, Jing Xu, Yudong Jing, Xuezhao Liu, Hui Xiao, Chonglin Yang.
Arf GTPases antagonize the Frizzled/Planar cell polarity pathway to regulate the asymmetric cell division of the Q.p neuroblast. Jerome Teuliere, Aakanksha Singhvi, Shaun Cordes, Karla Talavera, Gian Garriga.
Sensory input modulates ciliary receptor localization and IFT activity. Juan Wang, Natalia Morsci, Maureen Barr.
Regulation of Rab GTPase-mediated endosomal trafficking by TBC-2. Xiaolin A. Wang, Farhad Karbassi, Marc-André Sylvain, Krittika Bhende, Anna Chavlovski, Christian E. Rocheleau.
The BBSome regulates IFT particles turn-around at cilia tip. Qing Wei, Yuxia Zhang, Yujie Li, Jinghua Hu.
A novel basal body protein DYF-17 controls the ciliary entry of DYF-11 and IFT assembly. Qing Wei, Jinghua Hu.
Unraveling the VAP MSP secretion mechanism. Jessica L. Winek, Michael Miller.
Cis- and trans-regulatory mechanisms of ciliary targeting in a subset of chemosensory neurons in C. elegans. Martin Wojtyniak, Piali Sengupta.
LET-99, a novel G protein regulator for asymmetric division. Dae Hwi Park, Anna Ye, Lesilee S. Rose.
RAB-6 and the Retromer Complex Regulate Glutamate Receptor Recycling Through A Retrograde Transport Pathway. Donglei Zhang, Nora R. Isack, Doreen R. Glodowski, Barth D. Grant, Christopher Rongo.
qx193 affects lysosome dynamics and motility in C. elegans. Wei Zou, Baohui Chen, Bin Liu, Xiaochen Wang.
Cell Biology: Morphogenesis, migration, cytoskeleton
In vivo analysis of epithelial cell polarization. Stephen Armenti, Jeremy Nance.
Two parts of Caenorhabditis elegans glypican LON-2 negatively regulate a BMP-like pathway and require membrane proximity. S. Bageshwar, T. Gumienny.
CPNA-1, a novel copine domain containing protein, links the integrin associated protein PAT-6 (Actopaxin) to the giant protein UNC-89 (obscurin) in C. elegans muscle. Ge Xiong, Adam D. Warner, Hiroshi Qadota, Donald G. Moerman, Guy M. Benian.
The giant protein UNC-89 (obscurin) interacts with CUL-1: implications for ubiquitin mediated protein degradation in muscle. M. Berenice Duran, Hiroshi Qadota, Kristy J. Wilson, Guy M. Benian.
Morphogenesis of the C. elegans intestine depends on the ability of Arp2/3 to promote membrane association of apical proteins. Yelena B. Bernadskaya, Falshruti Patel, Hiao-Ting Hsu, Martha Soto.
Control of Distal Tip Cell Migration in C. elegans through the Interaction of Dishevelled Proteins and CACN-1. Lauren Byrnes, Melissa LaBonty, Erin Cram.
TOCA-1 and actin polymerization contribute to P-cell nuclear migration. Yu-Tai Chang, Daniel A. Starr.
The Anal Depressor Undergoes Morphological and Functional Changes during Caenorhabditis elegans Male Development. Xin Chen.
An E-Cadherin-mediated hitchhiking mechanism for C. elegans germ cell internalization during gastrulation. Daisuke Chihara, Jeremy Nance.
The minus-end actin capping protein, TMD-1/tropomodulin, regulates the morphology of the intestine and excretory cell. Corey Hoffman, Clarence Ling, Gary Mantione, Nicole Vissichelli, Vincent Cannataro, Thomas Gallagher, Elisabeth (Abbi) Cox.
Roles for anillin (ani-1) in regulating cell shape changes during C. elegans embryogenesis. Nellie Fotopoulos, Neetha Makil, Yun Chen, Alisa Piekny.
Isolation, characterization, and whole genome sequencing of a mutant defective for the pharyngeal g1a gland sub-type. Vikas Ghai, Stephane Flibotte, Jeb Gaudet.
Investigations into the collective movement of substrate neurons and epidermis during ventral enclosure. Claudiu Giurumescu, Andrew Chisholm.
Searching for interactors and substrates of the PXN-2 extracellular matrix peroxidasin. Jennifer R. Gotenstein, Andrew D. Chisholm.
Mechanisms Involved in Regulating the Activity and Localization of a Microtubule-depolymerizing Kinesin in the One-cell Stage C. elegans Embryo. X. Han, K. Cheung, M. Srayko.
DPY-24 regulates the timing of DTC dorsal turn. Tsai-Fang Huang, Chun-Yi Cho, Jheng-Wei Huang, Yi-Chun Wu.
A C.elegans pathology model of Leucine-rich repeat kinase 2 (LRRK2). Xu Huang, Enrico Schmidt, Ralf Baumeister.
The C.elegans spectraplakin VAB-10 regulates nuclear migration by linking actin and microtubule cytoskeleton in the gonadal distal tip cells. H.-S. Kim, R. Murakami, S. Quintin, M. Mori, K. Tamai, K. Ohkura, M. Labouesse, H. Sakamoto, K. Nishiwaki.
Investigating the role of CACN-1 in the Canonical Wnt Signaling Pathway. Melissa LaBonty, Mouna Ibourk, Erin Cram.
The F-Bar and Rho GTPase-activating protein RGA-7 controls CDC-42 activity during embryonic elongation in Caenorhabditis elegans. Germain Lacoste-Caron, Sarah Jenna, Emmanuel Martin.
A genetic screen to elucidate the role of a PP2A phosphatase required for mitotic spindle assembly. Karen I. Lange, Martin Srayko.
An enhancer screen to identify genes that function with UNC-6/UNC-40 (netrin) to promote anchor cell invasion. Lauren R. Lilley, Quiyi Chi, David R. Sherwood.
Molecular characterization of the C. elegans anillin isoforms. Michael Loloyan, Alisa Piekny.
The roles of rhgf-2/Rho GEF and fhod-1/formin in regulating the actin cytoskeleton during embryonic elongation. Simon K. Rocheleau, Christopher A. Vanneste, Eko Raharjo, Robert Steven, David Pruyne, Paul E. Mains.
Extracellular leucine-rich repeat proteins and maintenance of epithelial integrity. Vincent P. Mancuso, Jean Parry, Luke Storer, Corey Poggioli, David Hall, Meera Sundaram.
The PCP pathway components vang-1 and prkl-1 are required for the Wnt dependent migration of the Q neuroblasts descendants. Remco A. Mentink, Hendrik C. Korswagen.
madd-2 regulates anchor cell invasion. Matthias Morf, Ivo Rimann, Stefanie Nusser, Mariam Alexander, Peter Roy, Alex Hajnal.
Infection-induced plasticity of hindgut development. Frederick A. Partridge, Jonathan Hodgkin.
A possible role for TRY-2/plasminogen during C. elegans embryonic development. Melissa Ponce, Austin Howard, Saeideh Sarraf-Mamouri, Martin Hudson.
The C. elegans Hailey-Hailey disease homolog pmr-1 is essential for embryonic development. Vida Praitis, Adityarup Chakravorty, Charlotte Feddersen, Dae Gon Ha, Leah Imlay, Sarah Kniss, Walter Liszewski, Michael Miller, Juliet Mushi, Angela Schacht, Tyson Stock, Alexander Sullivan-Wilson, Zelealem Yilma, Lensa Yohannes, Jeffrey Simske.
PAT-4 (ILK) regulates the binding of UNC-112 (Kindlin) to PAT-3 (β-integrin) in C. elegans. Hiroshi Qadota, Donald G. Moerman, Guy M. Benian.
Microtubules in embryonic morphogenesis. Sophie Quintin, Ambre Bender, Michel Labouesse.
Somatic gonad precursor migration in C. elegans. Monica R. Rohrschneider, Jeremy Nance.
The role of extracellular ZP-domain protein DYF-7 in body size development. Robbie D. Schultz, Tina L. Gumienny.
UNC-83 and UNC-84 bridge the nuclear envelope to move nuclei. Daniel A. Starr, Erin Tapley, Heidi Fridolfosson, Marina Meyerzon, Nina Ly.
The Rac-GEF UNC-73/TRIO Mediates Multiple and Genetically Distinct Pathways to regulate excretory cell migration. Nancy Marcus, Eve Stringham.
The Nm23-H1/H2 homologue NDK-1 activates Ras/MAPK signaling interacting with kinase scaffold of Ras during vulval development in C. elegans. Krisztina Takacs-Vellai, Neda Masoudi, Luca Fancsalszky, Ehsan Pourkarimi, Tibor Vellai, Anton Gartner, Anita Alexa, Attila Remenyi, Anil Mehta.
Mutations Affecting Cessation of Gonadal Leader Cell Migration in C. elegans. Kikuchi Tetsuhiro, Shibata Yukimasa, Nishiwaki Kiyoji.
GSK-3 Regulates Left/Right Symmetry Breaking. Michael G. Tiongson, Christian Pohl, Zhirong Bao.
Caenorhabditis elegans RHGF-2 is an essential RHO-1 specific RhoGEF that binds to the multi-PDZ domain scaffold protein MPZ-1. Thuy Tran, Li Lin, Shuang Hu, Todd Cramer, Vera Hapiak, Richard Komuniecki, Robert Steven.
SUMO proteases in C. elegans. A. Tsur, L. Broday.
VAB-3 and VAB-5 are involved in mediating embryonic anterior muscle development. Ryan D. Viveiros, Robert Barstead, Donald G. Moerman.
Analysis of UNC-6/netrins effectors during C. elegans anchor cell invasion. Zheng Wang, David Sherwood.
Screening for essential muscle genes and synthetic lethality using high-throughput RNAi. Adam D. Warner, Teresa Rogalski, Aruna Somasiri, Iasha Chaudhry, Donald G. Moerman.
Essential Functions of IFA-2 Domains in C. elegans Fibrous Organelles. Kyle C. Williams, John Plenefisch.
Novel regulation of the CUL-3/MEL-26 protein degradation pathway by the giant protein UNC-89. Kristy J. Wilson, Hiroshi Qadota, Paul E. Mains, Guy M. Benian.
Analysis of immunogenic proteins in C. elegans (IV). A. Yamakawa, M. Ushiro, T. Tanaka, J. Fukumoto, A. Tamura.
Cell Biology: Cell division and chromosome dynamics
Analysis of Protease-Dead Separase: Development of a New Method to Study Dominant-Negative Transgenes. Joshua N. Bembenek.
Breaking It Down: Investigating Synaptonemal Complex Disassembly In C. elegans Using RNAi. Heather M. Brockway, Sarit Smolikove.
Cytosolic Aminopeptidase P (APP-1): a possible role in meiotic progression in Caenorhabditis elegans. Hannah Craig, Enrique Martinez-Perez, Darren Brooks, R. Elwyn Isaac.
Distinct Roles for the Kinesins BMK-1 and KLP-18 in Bipolar C. elegans Oocyte Meiotic Spindle Assembly. Valerie R. Osterberg, Meredith H. Price, Sara N. Christensen, Bruce A. Bowerman.
A member of the DOG-1 family is essential for normal cell division. George Chung, Ann Rose.
GSP-3 and GSP-4 are required for sperm meiotic chromosome segregation in C. elegans. Thais Godoy Cintra, Jui-Ching Wu, Aiza Go, Diana Chu.
FBF-mediated repression of the Cip/Kip cell cycle inhibitor CKI-2 promotes self-renewal of C. elegans germline stem cells. Irene Kalchhauser, Brian Farley, Sandra Pauli, Sean Ryder, Rafal Ciosk.
A screen for C. elegans oocyte meiotic spindle-defective mutants. Amy Connolly, John Yochem, Josh Lowry, Bruce Bowerman.
Characterization of the role of TLK-1 in kinetochore assembly in C. elegans. Jessica M. De Orbeta, Tokiko Furuta, Jill M. Schumacher.
Identifying the role of the Tousled-like kinase during the cell cycle. Jason R. Ford, Tokiko Furuta, Henry Adams, Jill M. Schumacher.
Asymmetric chromosome behavior during oocyte meiosis. Christina M. Glazier, Abby F. Dernburg.
A Polo-like kinase coordinates meiotic chromosome dynamics. Nicola C. Harper, Regina Rillo, Sara Jover-Gil, Needhi Bhalla, Abby F. Dernburg.
CRL2ZYG-11 and cyclin B degradation. Cassandra S. Heighington, Edward T. Kipreos.
SEP-1 and CED-3 regulate apoptosis and separation of sister chromatids in C. elegans. Pan-Young Jeong, Kumar Ashish, Pradeep M. Joshi, Joel H. Rothman.
Genetic and molecular investigation of the Fanconi Anemia pathway in C. elegans. Martin R. Jones, Ann M. Rose.
Local meiotic recombination rate variation in Caenorhabditis elegans. Taniya Kaur, Matthew Rockman.
ZTF-8 is required for DNA double-strand break repair and DNA damage response in the germline in coordination with the 9-1-1 DNA damage checkpoint. Hyun-Min Kim, Monica Colaiacovo.
Investigating the role of Aurora kinases during meiotic prophase in C. elegans. Y. Kim, A. Dernburg.
Determining Whether Autosomes and the X Chromosome have Distinct Genetic Requirements for Synapsis Checkpoint Activation in C. elegans. Piero Lamelza, Needhi Bhalla.
Spindle assembly checkpoint plays a role in DNA-damage-induced cell cycle arrest in C. elegans male germline. Kate Lawrence.
SPD-1-centralspindlin interaction is critical for maintaining the mechanical integrity of the central spindle against cortical pulling forces. K.-Y. Lee, M. Mishima.
βpat-3 integrin is involved in regulation of CKI-1. Shingo Kihira, Eunjeong Yu, Jessica Cunningham, Myeongwoo Lee.
Condensin-mediated chromosome architecture and crossover regulation. Teresa W. Lee, Barbara J. Meyer.
A Genetic Screen for Temperature-Sensitive, Embryonic Lethal Mutations in C. elegans. Josh Lowry, John Yochem, Amy Connolly, Bruce Bowerman.
him-5 functions in crossover control and DNA Damage Repair. Olivia McGovern, Kristie Jolliffe, Philip Meneely, Brent Derry, Judith Yanowitz.
Novel Protein SPE-7 is Required for Meiotic Chromosome Segregation and Fibrous Body Assembly. Kari Messina, Marc Presler, Diane C. Shakes.
Identification and characterization of new nuclear envelope proteins. Adela Morales-Martinez, Cristina Ayuso, Peter Askjaer.
Identification and functional analysis of histone demethylase activity in response to UV-induced DNA damage in Caenorhabditis elegans. Toshia Myers, Alexandra Avram, Lisa Sacini.
ZHP-3 is a ubiquitin E3 ligase with multiple roles in meiosis. Cate Randall Paschal, Christian Nelson, Needhi Bhalla.
Role of SPD-3 in Pairing and Synapsis of Meiotic Chromosomes. Regina Rillo, Abby Dernburg.
Quantitative analysis of chromosome dynamics during C. elegans meiosis. O. Rog, D. J. Wynne, A. F. Dernburg.
A novel gene promoting meiotic double-strand break formation in C. elegans. Simona Rosu, Anne Villeneuve.
Multiple developmental processes collaborate to regulate cdc-14 activity. Sarah Roy, Mako Saito.
Characterizing the meiotic role of protein phosphatase 4. Aya Sato, Fumio Motegi, Asako Sugimoto, Peter Carlton.
Insulin signalling functions as somatic DNA damage checkpoint during development. Michael Müller, Maria Ermolaeva, Peter Frommolt, Sebastian Greiss, Jennifer Schneider, Bjoern Schumacher.
Regulation of Meiotic Double-Strand Break Formation in C. elegans. Ericca Stamper, Abby Dernburg.
The C. elegans adenomatous polyposis coli tumor suppressor homolog APR-1 prevents chromosomal instability by regulating centrosome duplication. Attila Stetak, Erika Froehli-Hoier, Alex Hajnal.
PKC-3 aPKC phosphorylates LIN-5 NuMA to position the mitotic spindle during asymmetric division. Matilde Galli, Javier Muńoz, Vincent Portegijs, Mike Boxem, Albert Heck, Sander van den Heuvel.
Purification of intact germline nuclei: Towards a high-resolution spatiotemporal map of meiotic chromatin in C. elegans. Christina M. Whittle, Abby F. Dernburg.
CDC-48/p97 is required for meiotic chromosome segregation in C. elegans. Yohei Sasagawa, Teru Ogura, Kunitoshi Yamanaka.
A mutation in cya-1, which encodes the C. elegans Cyclin A homolog, specifically affects the division of the NSM neuroblast. Bo Yan, Barbara Conradt.
Illuminating the Formation and Regulation of Meiotic Crossovers with GFP:COSA-1. Karl Zawadzki, Rayka Yokoo, Anne Villeneuve.
HAL-2 promotes homologous pairing during C. elegans meiosis by antagonizing inhibitory effects of SC proteins. Weibin Zhang, A. J. MacQueen, N. Miley, M. Zastrow, A. M. Villeneuve.
Methods and Technology: Genetics
Mapping the PKD-2 localization defective mutant cil-2(my2). Deanna Michele De Vore, Juan Wang, Karla Knobel.
A new system for neuron-specific RNAi and its application to studying the function of essential genes in mature GABA neurons. Christopher Firnhaber, Marc Hammarlund.
MosSCI: Improved efficiency and new insertion sites. C. Frřkjćr-Jensen, MW Davis, M. Ailion, EM Jorgensen.
Development of three automated quantitative platforms for RNAi phenotyping. Andrew G. Fraser, Arun Ramani, Tungalag Chuluunbaatar, Hong Na.
MosSCI-biotic: neomycin resistance gene as a co-insertion marker for Mos1-mediated single-copy insertion (MosSCI). R. Giordano-Santini, D. Tu, R. Johnsen, D. Baillie, D. Dupuy.
Construction of Arrayed Toxicology Reporter Panels using Transcript-activated Fluorescent Reporters in Transgenic Nematodes. Miluka Gunaratna, John Manfredi, Christopher Hopkins.
A systematic screen for secreted proteins using a synthetic lethal approach. Samantha N. Hartin, Vi Leitenberger, Martin L. Hudson, Brian D. Ackley.
Low-copy integration of transgenes by TMP/UV methods. Eriko Kage-Nakadai, Hiroyuki Kobuna, Osamu Funatsu, Muneyoshi Ootori, Keiko Gengyo-Ando, Sawako Yoshina, Sayaka Hori, Shohei Mitani.
Simple and rapid single nucleotide polymorphism (SNP) mapping method in C. elegans without the use of restriction fragment length polymorphisms (RFLP) analysis - made it possible by real-time PCR and high-resolution melting curve analysis (HRM). Claudia Litterst, Luis Ugozzoli.
RAD mapping and genomic interval pulldown sequencing for rapid mutation identification. Sean O'Rourke, Doug Turnbull, Nick Stiffler, John Yochem, Amy Connelly, Josh Lowry, Michael Miller, Eric Johnson, Bruce Bowerman.
An altered method of feeding RNAi that knocks down multiple genes simultaneously in the nematode Caenorhabditis elegans. Yukari Omichi, Kenji Gouda, Yohei Matsunaga, Takashi Iwasaki, Tsuyoshi Kawano.
Incorporating Unnatural Amino Acids in C. elegans. Angela Parrish, Xingyu She, Zheng Xiang, Irene Coin, Andrew Dillin, Lei Wang.
A Three-pronged Method Employing Caenorhabditis elegans for Large Scale Screening of Potential Pharmacological Agents against Alzheimers Disease. Shreesh Raj Sammi, Supinder Kaur, Pooja Jadiya, Aamir Nazir.
Update on the use of drug selection in nematodes. Jennifer I. Semple, Ben Lehner.
High throughput identification of mutations affecting aggregation using a novel Illumina sequencing analysis pipeline. Katherine P. Weber, Felix Baier, Subhajyoti De, Mario de Bono.
Methods and Technology: Imaging
Computer automated forward-genetic screening using sub-cellular fluorescent reporters. Matthew M. Crane, Peri T. Kurshan, George J. Wang, Jeffrey N. Stirman, Kang Shen, Hang Lu.
Automated sub-cellular imaging for drug screening in C. elegans. Francesca Farina, Betty Peignelin, Rémi Vernet, Clément Meiller, Frédéric Parmentier, Christian Néri.
High-resolution in vivo Ca2+ imaging of neuromuscular system in Caenorhabditis elegans. K. Gengyo-Ando, A. Usami, Y. Nagamura, Y. Yoshida, N. Matsuki, Y. Ikegaya, J. Nakai.
Endrov - an open source framework for image processing and analysis. Johan Henriksson, Jürgen Hench, Thomas R. Bürglin.
In vivo calcium imaging of the pharyngeal muscles in freely moving animals. I. Kotera, L. Su, S. Wong, K. Truong, H. Suzuki.
The Metal Biology of C. elegans. Gawain McColl, Simon James, Blaine Roberts, Martin de Jonge, Robert Cherny, Ashley Bush.
The GLOWorm repository and GLOWormJ: a system for distribution and analysis of multidimensional embryological images. William A. Mohler, Ion Moraru, Ariel B. Isaacson, Frank Morgan, Dan Vasilescu, Jeffrey Dutton, Glenn Duzy.
Investigation of Low-cost Fluorescence Microscopy. Andy Papp, Chris Aldrich, David Perry.
Characterizing development by lineage tracing. Julia L. Richards, Joshua Burdick, Travis Walton, Elicia Preston, John Murray.
Subcellular in vivo time-lapse imaging and optical manipulation of C. elegans in standard multiwell plates. Christopher Rohde, Mehmet Fatih Yanik.
Cell lineaging for single cell, high throughput analysis. Anthony Santella, Zhirong Bao.
Development of a High Throughput Infrared Detection Method for Toxicity and Pharmacological Testing in C. elegans. Dario R. Bichara, Sergio H. Simonetta.
Addition of the genetically encoded, red-shifted Ca2+ sensor RCaMP to the C. elegans optogenetic toolbox. Sebastian Wabnig, Jasper Akerboom, Jeffrey Stirman, Hang Lu, Loren Looger, Alexander Gottschalk.
Automated alignment of TEM image stacks to simplify anatomical reconstruction. Greg Hood, Arthur Wetzel, Meng Xu, David Hall, Scott Emmons.
Rapid and accurate phenotyping of embryonic lethality via image analysis of C. elegans developmental stages from high-throughput image data. Amelia G. White, Huey-Ling Kao, Patricia G. Cipriani, Eliana Munarriz, Annalise Paaby, Davi Geiger, Eduardo Sontag, Kristin C. Gunsalus, Fabio Piano.
Methods and Technology: Gene expression profiling and ChIP
Cell type-specific profiling of the transcriptome in C. elegans. Meenakshi K. Doma, Igor Antoshechkin, Paul Sternberg.
A method for purifying nuclei from different tissues. Florian A. Steiner, James R. Priess, Steven Henikoff.
An assessment of the quality of histone-modification antibodies. Thea Egelhofer, Aki Minoda, Sarit Klugman, Kyungjoon Lee, Paulina Kolasinska-Zwierz, Julie Ahringer Lab, Mitzi Kuroda Lab, Sarah Elgin Lab, Mark Perry Lab, Vincenzo Pirrotta Lab, Bing Ren Lab, Susan Strome, Peter Park Lab, Gary Karpen Lab, R. David Hawkins, Jason Lieb.
Methods and Technology: Proteomics and metabolomics
Revising the DAF-12 ligand biosynthetic pathway in C. elegans: A comprehensive NMR-based approach. Neelanjan Bose, Parag Mahanti, Axel Bethke, Joshua Judkins, Joshua Wollam, Adam Antebi, Patrick Hu, Frank Schroeder.
Optimising metabolic profiling approaches towards an improved understanding of metabolism during development and aging in C.elegans. Florian M. Geier, Gabriel Valbuena, Sarah K. Davies, Jake G. Bundy, Armand M. Leroi.
Connecting genotype with metabotype in C. elegans: 2D-NMR based metabolomics uncovers small molecules dependent on peroxisomal beta-oxidation via DAF-22. Yevgeniy Izrayelit, Steven Robinette, Arthur Edison, Frank Schroeder.
Second generation synthesis and bioactivity of novel endogenous ligands of the nuclear hormone receptor DAF-12. Joshua C. Judkins, Neelanjan Bose, Parag Mahanti, Jacob Hoffman, Frank Schroeder.
SILAN - an Effective Method for Quantitative Proteomics in C. elegans . M. Larance, A. Bailly, A. Gartner, A. I. Lamond.
Measuring Protein Abundance across Developmental Stages of C. elegans via Molecular Weight Fractionation and High-Resolution Mass Spectrometry. Gennifer E. Merrihew, Giana Angelo, Michael J. MacCoss.
Searching for DAF-16 partners. A. Nazari Daftari, Y. Wang, R. Baumeister.
Comprehensive analysis of C. elegans ascarosides, a modular library of small molecule signals. Stephan von Reuss, Jagan Srinivasan, Neelanjan Bose, Paul Sternberg, Frank Schroeder.
Proteomic profiling dietary restriction pathways with 13C-labeled Caenorhabditis elegans. Y. Yuan, C. Kadiyala, T. Ching, S. Saha, H. Xu, K. Kramp, R. Ewing, A. Hsu, M. Miyagi, Z. Feng.
Methods and Technology: Databases and programs
A Website to Annotate SNP Data. John Rummage, Kenneth G. Miller, Robert J. Barstead.
The Virtual Worm: A Three-Dimensional Model of the Anatomy of Caenorhabditis elegans at Cellular Resolution. Christian A. Grove, Paul W. Sternberg.
Hey, you, get ON our cloud: easy private installations of WormBase through cloud computing. Todd W. Harris.
New and Improved: WormImage 2.0 and WormAtlas Mobile. L. A. Herndon, Z. F. Altun, C. A. Wolkow, K. Fisher, C. Crocker, T. Stephney, M. Xu, D. H. Hall.
Synthesizing Biological Theories. Cory Plock, Andy Roberts, Hillel Kugler.
The Biogemix knowledge base project: cross-species and network-based data integration for Huntingtons disease research. François-Xavier Lejeune, Lilia Mesrob, Frederic Parmentier, Cédric Bicep, Jean-Philippe Vert, Christian Neri.
OrthoList, a compendium of C. elegans genes with human orthologs. Daniel Shaye, Iva Greenwald.
Methods and Technology: Microfluidics and neural methods
Exploiting Simple Geometries in Microfluidic Chips to Orient C. elegans for Rapid Visual Screens. Ivan Cáceres, Nick Valmas, Massimo Hilliard, Hang Lu.
Effects of electrical stimulation on the ASH chemosensory neuron in Caenorhabditis elegans. Trushal V. Chokshi, Nikos Chronis.
Red-shifted optical excitation with a Chlamydomonas / Volvox hybrid Channelrhodopsin. Karen Erbguth, Matthias Prigge, Franziska Schneider, Jeffrey N. Stirman, Hang Lu, Peter Hegemann, Alexander Gottschalk.
Large-scale in vivo laser neurosurgery for discovery of small-molecule enhancers of regeneration. Cody L. Gilleland, Christopher B. Rohde, Chrystanthi Samara, Stephanie Norton, Stephen J. Haggarty, Mehmet Fatih Yanik.
Microfabricated device for acute drug treatment in the early C. elegans embryos. Alex Groisman, Ana Carvalho, Sara Olson, Edgar Gutierrez, Kelly Zhang, Lisa Noble, Arshad Desai, Karen Oegema.
Microfluidic vacuum actuated trap for gentle immobilization and high-resolution microscopy of C. elegans across developmental stages. Edgar Gutierrez, Rebecca Green, Karen Oegema, Alex Groisman.
Design of a C. elegans sorting microchip based on structure dependent swimming behavior. Bicheng Han, Daeyeon Kim, Jennifer H. Shin.
A multi-worm optogenetic system. Yuya Kawazoe, Hiromu Yawo, Kotaro Kimura.
A simple microfluidic device for long-term in vivo imaging of mitochondrial dynamics in C. elegans. Sudip Mondal, Sandhya Koushika.
A 96-well plated based liquid phase C. elegans behavioral quantification system. Maohua Zheng, Olga Gorelenkova, Zhaoyang Feng.
Methods and Technology: Other nematodes
Nicotine exposure response in Caenorhabditis elegans: a model for evaluating smoking cessation agents. Danny Tudor, Aaron Behm, David Montgomerie, Chad Ahia, Patrick Yasukawa, Supakit Wongwiwatthananukit, Anthony Otsuka, Leng Chee Chang.
Identification of a New Ascaroside, Female Attracting Pheromone in Panagrellus redivivus. Tatsuji Chuman, Ramadan Ajredini, Hans Alborn, Andrea Choe, Stephan von Reuss, Fatma Kaplan, Frank C. Schroeder, Paul W. Sternberg, Arthur S. Edison.
The Characterization of Enhanced Environmental RNAi Mutants in Pristionchus pacificus. Jessica Cinkornpumin, Jeffrey Shibata, Maryn Cook, Neomal Muthumala, Ray Hong.
Mass Spectrometric Imaging and Behavioral Assays of Pristionchus pacificus. Chaevien S. Clendinen, Ramadan Ajredini, Robert Menger, Ghulam Khan, Richard Yost, Arthur S. Edison.
Classification and population analyses of soil nematodes by using an improved barcode-sequencing method. Toshihiko Eki, Erika Miyazaki, Shoko Yoshimitsu, Hisashi Morise.
Update: Progress made toward clinical use of the Bacillus thuringiensis (Bt) Cry5B protein as an anthelmintic. Brian L. Ellis, Yan Hu, Ying Liu, Raffi Aroian.
Crystal structure and function of novel nematicide Bacillus thurigiensis Cry5B. Hui Fan, Yan Hu, Alan Kelleher, Raffi Aroian, Partho Ghosh.
Exploring the Biological Targets of a Novel Class of Stilbenoid Compounds with Anthelmintic Activity. J. A. Miskowski, O. Awoyinka, M. Gross, A. Monte.
A can of worms - challenges and strategies for next generation nematode genomics. Michael Paulini.
Unveiling the unique biology of nematodes living in a cold methane seep on the ocean floor and their symbiosis with chemosynthetic bacteria. Amir Sapir, Adler R. Dillman, Manuel Mundo-Ocampo, James G. Baldwin, Victoria J. Orphan, Paul W. Sternberg.
Characterizing wild nematode isolates in an undergraduate research lab. Robin L. Hill.
Application of medium-throughput mutagenesis techniques in the molecular laboratory environment. Jonathan E. Karpel, J. Cole Rasch.
A writing intensive Caenorhabditis elegans laboratory exercise for undergraduates examining oxidative stress and antioxidants. Taylor Bell, Justine Betzu, Loreal Brown, Marissa Fontana, Christopher Frymoyer, Christina Hamilton, Amy Hartl, Lauren King, Amanda March, Caitlyn McLarnon, Lauren Meeley, Kathleen Murley, Katherine Murphy, Matthew Pall, Rabiul Ryan, Erin Slaunwhite, Rebecca E. Kohn.
Problem-solving and project-assisted learning of genetics, molecular biology and biological pathways in the study of Protein Kinase C in C.elegans. Marianne Land.
Using Nematodes for Discovery Based Learning. Candace C. LaRue, Pamela Padilla.
Student Projects using C. elegans to Investigate Animal Physiology. Tim H. Lindblom.
Using C. elegans as a model to assay bacterial pathogenesis in an undergraduate research survey course. Edith M. Myers, June H. Middleton.
Combining old fashioned gene mapping and new fangled genetic analysis in an upperlevel Genetics course. Maureen A. Peters, Katherine Cullen.
Using C. elegans to teach transmission genetics in a large introductory biology lab. Penny L. Sadler, Diane C. Shakes.
Preparing Undergraduates to Work at the Intersection of Biology and Mathematics. Timothy D. Walston, Barbara Kramer, Jason Miller.
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